Oral Paclitaxel definition

Oral Paclitaxel means the Product oral paclitaxel and encequidar, together with any improvements or modifications thereto.
Oral Paclitaxel means the P-gp inhibitor encequidar and oral paclitaxel.

Examples of Oral Paclitaxel in a sentence

  • There were also more gastro-intestinal side effects in the Oral Paclitaxel group.

  • Tyto osady by vzájemně spolupracovaly a prováděly směnu na základě pracovních poukázek.

  • In the study, the Oral Paclitaxel group had lower incidence and severity of neuropathy compared to IV paclitaxel: 57% of IV paclitaxel patients experienced neuropathy (all grades) versus 17% of Oral Paclitaxel patients, with grade 3 neuropathy observed in 8% of IV paclitaxel patients versus 1% of Oral Paclitaxel patients.

  • The results also showed lower incidence of alopecia, arthralgia and myalgia in the Oral Paclitaxel group.

  • Sagard may also terminate the Revenue Interest Financing Agreement if we have not received marketing authorization for Oral Paclitaxel by the FDA for the treatment of metastatic breast cancer by December 31, 2021.Sagard and its co-investors OPB SHRP Co-Invest Credit Limited and SIMCOE SHRP Co-Invest Credit Ltd.

  • In exchange for the Product Payment, we have agreed to make payments to Sagard (the “Payments”) equal to 5.0% of our world-wide net sales of Oral Paclitaxel, subject to a hard cap equal to the lesser of 170% of the Product Payment and the Put/Call Price set forth below (the “Hard Cap”).

  • No Obligor will, nor will it permit any of its Subsidiaries to, enter into or become or remain bound by any outbound exclusive license of Intellectual Property relating to U.S. commercialization rights to the Product Oral Paclitaxel, except for Permitted Licenses.

  • Oral Paclitaxel also showed statistically significant improvement compared to IV paclitaxel based on other analyses on populations excluding non- evaluable patients (which would give higher response rates), with p-values ≤ 0.01 in all analyses.

  • We are excited by the positive results in the Phase III pivotal study, demonstrating improved ORR for Oral Paclitaxel compared to IV paclitaxel across a full spectrum of analyses and lower incidence of neuropathy in the Oral Paclitaxel group.

  • Based on the data cut-off on July 25, 2019, there was a strong trend in progression- free survival (p = 0.077) favoring Oral Paclitaxel over IV paclitaxel, and a strong trend in overall survival (p = 0.11) favoring Oral Paclitaxel over IV paclitaxel.

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