Organic acid disorders definition

Organic acid disorders means disorders of metab- olism characterized by the accumulation of nonamino organic acids and toxic intermediates. This may lead to met- abolic crisis with ketoacidosis, hyperammonemia and hypo- glycemia resulting in severe neurological and physical dam- age and possibly death. For the purpose of this chapter organic acid disorders include: 3-OH 3-CH3 glutaric aciduria (HMG), beta-ketothiolase deficiency (BKT), glutaric acide- mia type I (GA 1), isovaleric acidemia (IVA), methylmalonic acidemia (CblA,B), methylmalonic acidemia (mutase defi- ciency) (MUT), multiple carboxylase deficiency (MCD), and propionic acidemia (PROP).
Organic acid disorders means 3-OH 3-CH3 glu- taric aciduria (HMG), beta-ketothiolase deficiency (BKT), glutaric acidemia type I (GA 1), isovaleric acidemia (IVA), methylmalonic acidemia (CblA,B), methylmalonic acidemia (mutase deficiency) (MUT), multiple carboxylase deficiency (MCD), and propionic acidemia (PROP). These disorders can lead to metabolic crises resulting in severe nerve damage, physical damage, and possibly death.
Organic acid disorders means disorders of metab- olism characterized by the accumulation of nonamino organic acids and toxic intermediates. This may lead to met- abolic crisis with ketoacidosis, hyperammonemia and hypo- glycemia resulting in severe neurological and physical dam- age and possibly death. For the purpose of this chapter organic acid disorders include: 3-OH 3-CH3 glutaric aciduria (HMG), beta-ketothiolase deficiency (BKT), glutaric acide- mia type I (GA 1), isovaleric acidemia (IVA), methylmalonic

Examples of Organic acid disorders in a sentence

  • Thanks for the opportunity to serve Academic Calendar Resolution Presented by:Professor Jeffrey J.

  • If undetected and untreated, fasting, infection or stress may trigger acute hypoglycemia leading to physical and neurological damage or death.)) (11) "Organic acid disorders" means disorders of metabolism characterized by the accumulation of nonamino organic acids and toxic intermediates.

  • POLICY GUIDELINES BACKGROUND Organic Acids Organic acids are metabolic intermediates that are produced in pathways of central energy production, detoxification, neurotransmitter breakdown, or intestinal microbial activity.1 Organic Acid Disorders Organic acid disorders are rare inherited conditions that cause a buildup of toxic organic acid intermediates.2,3 This is due to enzyme deficiencies that limit the body’s ability to breakdown certain amino acids.

  • To confirm breakage in the genes after exposure, metaphase spreads were made and chromosomes were scored for disruption of the probe (Figure 2.1d).

  • Organic acid disorders" means disorders of metabolism char­ acterized by the accumulation of nonamino organic acids and toxic in­ termediates.

  • ALEXANDER (Pietermaritzburg) for checking the English of our manuscript.


More Definitions of Organic acid disorders

Organic acid disorders means disorders of metabolism char­ acterized by the accumulation of nonamino organic acids and toxic in­ termediates. This may lead to metabolic crisis with ketoacidosis, hy­ perammonemia and hypoglycemia resulting in severe neurological and physical damage and possibly death. For the purpose of this chapter organic acid disorders include: 3-OH 3-CH3 glutaric aciduria (HMG), beta-ketothiolase deficiency (BKT), glutaric acidemia type I (GA 1), isovaleric acidemia (IVA), methylmalonic acidemia (CblA,B), methylma­ lonic acidemia (mutase deficiency) (MUT), multiple carboxylase defi­ ciency (MCD), and propionic acidemia (PROP).

Related to Organic acid disorders

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