Sphingosomal Vincristine definition

Sphingosomal Vincristine means a liposome that includes sphingomyelin and cholesterol and contains encapsulated vincristine, wherein the sphingomyelin comprises less than 20% dihydrosphingomyelin.
Sample 1Sample 2Sample 3

Examples of Sphingosomal Vincristine in a sentence

  • For example, the milestone payment described in subparagraph (a) above will be due only once, following the FDA’s acceptance for review of the Sphingosomal Vincristine NDA.

  • All Sphingosomal Vincristine R&D Expenses shall be subject to audits by INEX using reasonable and customary audit procedures in order to verify the amounts thereof.

  • No additional milestone payments to INEX shall be due from Hana pursuant to subparagraph (a) in connection with any subsequent NDA submission by Hana relating to Sphingosomal Vincristine.

  • The payments provided under this Article 3 are in addition to the portion of the Closing Payment and Closing Shares attributable to each of Sphingosomal Vincristine, Sphingosomal Vinorelbine, and Sphingosomal Topotecan previously paid to INEX by Hana pursuant to the Asset Purchase Agreement.

  • For this son of mine was dead, and has come to life again; he was lost, and has been found.

  • All Sphingosomal Vincristine R&D Expenses shall be subject to audits by TEKMIRA using reasonable and customary audit procedures in order to verify the amounts thereof.

  • Sphingosomal Vincristine in CHOP +/- rituximab is a promising new treatment for patients with high-risk untreated aggressive non-Hodgkin's lymphoma (NHL): Follow-up results of a phase II study.

  • In the event Hana sublicenses its rights to Sphingosomal Vincristine after the FDA approves the Sphingosomal Vincristine NDA or a Designated EU State approves a Regulatory Submission that is equivalent to an NDA, INEX shall be entitled to receive [***] percent ([***]%) of any Sublicensing Revenue payable to Hana by such Sublicensee.

  • Hana shall pay to INEX milestones payments in respect of Sphingosomal Vincristine as follows: INFORMATION MARKED BY [***] HAS BEEN OMITTED PURSUANT TO A REQUEST FOR CONFIDENTIAL TREATMENT.

  • Hana acknowledges and agrees with INEX that the Definitive Agreements amount to a Commercialization Agreement (as defined in the Termination Agreement), and therefore upon receipt of a Regulatory Approval (as defined in the Termination Agreement) of Sphingosomal Vincristine, Hana will pay to Elan International Services, Ltd.

Related to Sphingosomal Vincristine

  • Nicotine means nicotinic alkaloids;

  • Cannabinoid means any of the chemical compounds that are the active constituents of marijuana.

  • Anaerobic digester means a liquid manure storage area that is constructed with the intent to capture and combust gas emissions resulting from the digestion of waste by microbes in anaerobic conditions. An anaerobic digester is a LMSA and is required to comply with all requirements applicable to LMSAs. Requirements specific to anaerobic digesters will be noted when applicable.

  • Vaccine means a specially prepared antigen which, upon administration to a person, will result in immunity and, specifically for the purposes of this rule, shall mean influenza and pneumococcal vaccines.

  • Pyrolysis means the thermal degradation of a substance in the absence of any oxidising agent, which does not form part of the substance itself, to produce char and gas and/or liquid; and

  • Total tetrahydrocannabinol means the same as that term is defined in § 3.2-4112.

  • Opioid antagonist means a drug that binds to opioid

  • Corrosion inhibitor means a substance capable of reducing the corrosivity of water toward metal plumbing materials, especially lead and copper, by forming a protective film on the interior surface of those materials.

  • haemophilia means an inheritable disease, usually affecting only male but transmitted by women to their male children, characterised by loss or impairment of the normal clotting ability of blood so that a minor would may result in fatal bleeding;

  • Tetrahydrocannabinol means the same as that term is defined in § 3.2-4112.

  • Cannabinoid edible means food or potable liquid into which a cannabinoid concentrate, cannabinoid extract or dried marijuana leaves or flowers have been incorporated.

  • Receptor means enclosed spaces, conduits, protected groundwater sources, drinking and non-drinking water wells, surface water bodies, and public water systems which when impacted by chemicals of concern may result in exposure to humans and aquatic life, explosive conditions or other adverse effects on health, safety and the environment as specified in these rules.

  • Isomer means all enantiomers and diastereomers.

  • coronavirus means severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2);

  • Therapeutic diet means meals served that are soft, low-fat, low-sodium or controlled calorie.

  • Opioid means a drug that produces an agonist effect on opioid receptors and is indicated or used for the treatment of pain.

  • Biological Samples means any physical samples obtained from Study Participants in accordance with the Protocol for the purposes of the Study.

  • Cyanoacrylate adhesive means any adhesive with a cyanoacrylate content of at least 95% by weight.

  • Prosthesis means an artificial substitute for a missing body part.

  • Salmonid means of, belonging to, or characteristic of the family Salmonidae, which includes the salmon, trout, and whitefish.

  • Parenteral means a sterile preparation of drugs for injection through one or more layers of the skin.

  • Genetic material means any material of plant, animal, microbial or other origin containing functional units of heredity.

  • Precursor means any chemical reactant which takes part at any stage in the production by whatever method of a toxic chemical. This includes any key component of a binary or multicomponent chemical system.

  • Epinephrine auto-injector means a device for immediate self-administration or administration by another trained person of a measured dose of epinephrine to a person at risk of anaphylaxis.

  • Infection means the entry and development or multiplication of an infectious agent in the body of humans and animals that may constitute a public health risk;

  • Halogen means one of the chemical elements chlorine, bromine or iodine.