Analysis of Tumor Mutational Landscape and Transcriptional Programs Sample Clauses

Analysis of Tumor Mutational Landscape and Transcriptional Programs. The change in the biomarkers in the pre- versus 6-week biopsies will be estimated for each patient. A two-sample t test will be used to compare the continuous changes between the two treatment arms, assuming that the differences are normally distributed. If they are non- normal, a Wilcoxon Rank Sum Test will be used. A sensitivity analysis will use a linear regression model to compare the two treatment arms, adjusted for the baseline level.
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