Common use of Compliance with Laws; Use Clause in Contracts

Compliance with Laws; Use. The Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants of the Building or interferes with the operation of the Building. Tenant shall comply with all Laws, including the Americans with Disabilities Act, regarding the operation of Tenant's business and the use, condition, configuration and occupancy of the Premises. Tenant, within 10 Business Days after receipt, shall provide Landlord with copies of any notices it receives regarding a violation or alleged violation of any Laws. Except to the extent properly included in Expenses, Landlord shall be responsible for the cost of correcting any violations of Title III of the Americans with Disabilities Act (ADA) with respect to the Common Areas of the Building. Notwithstanding the foregoing, Landlord shall have the right to contest any alleged violation in good faith, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by law. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply with the terms of any final order or judgment. Tenant shall comply with the rules and regulations of the Building attached as Exhibit B and such other reasonable rules and regulations adopted by Landlord from time to time. Tenant shall also cause its agents, contractors, subcontractors, employees, customers, and subtenants to comply with all rules and regulations. Landlord shall not knowingly discriminate against Tenant in Landlord's enforcement of the rules and regulations.

Compliance with Laws; Use. 5.01 The Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use of keep in the Premises for any purpose which is illegalsubstance defined as a “hazardous material” (collectively, dangerous to persons “Hazardous Materials”) by the United States of America, the State of California, the City or property County of San Francisco, or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants of political subdivision, agency or department having jurisdiction over the Building or interferes the Property (each, a “Governmental Authority”); provided however, Tenant may use and keep in the Premises reasonable quantities of customary general office materials which may otherwise constitute Hazardous Materials (i.e. toner and household cleaning supplies) that do not require a permit to use and/or store, provided that such Hazardous Materials are maintained in compliance with all applicable Laws (as defined below). To the operation best of Landlord’s knowledge, the Building is compliant with all Laws regarding Hazardous Materials and there are no existing Hazardous Materials at the Property as of the BuildingCommencement Date. Tenant shall comply with all Lawsstatutes, codes, ordinances, orders, rules and regulations of any municipal or governmental entity whether in effect now or later, including the Americans with Disabilities ActAct and any environmental laws or ordinances promulgated by any Governmental Authority (“Law(s)”), regarding the operation of Tenant's ’s business and the use, condition, configuration and occupancy of the Premises. TenantIn addition, within 10 Business Days after receiptTenant shall, shall provide Landlord at its sole cost and expense, promptly comply with copies of any notices it receives regarding a violation or alleged violation of any Laws. Except Laws that relate to the Building but only to the extent properly included in Expenses, Landlord shall be responsible for such obligations are triggered pursuant to Laws first enacted after the cost of correcting any violations of Title III Commencement Date and by Tenant’s particular use of the Americans with Disabilities Act (ADA) with respect to the Common Areas of the Building. Notwithstanding the foregoingPremises, Landlord shall have the right to contest any alleged violation in good faithother than for general office use, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by law. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations Alterations or improvements necessary to comply with in the terms of any final order Premises performed or judgmentrequested by Tenant. Tenant shall comply with the rules and regulations of the Building attached as Exhibit B D and such other reasonable rules and regulations adopted by Landlord from time to time. Tenant shall also cause its agents, contractors, subcontractors, employees, customers, and subtenants to comply with all including rules and regulations. regulations for the performance of Alterations (defined in Section 9.03), provided that Landlord shall not knowingly discriminate against Tenant in Landlord's enforcement provide reasonable prior written notice of the any such additional rules and regulationsregulations adopted by Landlord after the Commencement Date. In the event of a conflict between the express terms of this Lease and any rules and regulations adopted by Landlord after the date of this Lease, the terms of this Lease shall control.

Compliance with Laws; Use. The Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants of the Building or interferes with the operation of the Building. Landlord represents that, on the Commencement Date, the Common Areas and Premises shall comply with all applicable Laws, including, without limitation, the Americans with Disabilities Act Accessibility Guidelines for Buildings and Facilities (the "ADAAG") and with all applicable Regulations of the National Board of Fire Underwriters, including compliance and with the National Fire Code Bulletins, NFPA 30 (the Flammable and Combustible Liquids Code) and NFPA 45 (the standard for Fire Protection in Laboratories using Chemicals). Tenant shall comply with all applicable Laws, including, without limitation, the ADAAG and with all applicable Regulations of the National Board of Fire Underwriters, including Compliance and with the Americans with Disabilities ActNational Fire Code Bulletins, NFPA 30 and NFPA 45, as well as all applicable zoning laws regarding the operation of Tenant's business and the use, condition, configuration and occupancy of the PremisesPremises from and after the Commencement Date. TenantTenant and Landlord, within 10 Business Days days after receipt, shall each provide Landlord the other with copies of any notices it receives regarding a violation or alleged violation of any Laws. Except to the extent properly included in Expenses, Landlord shall be responsible for the cost of correcting any violations of Title III of the Americans with Disabilities Act (ADA) Laws with respect to the Common Areas of the Building. Notwithstanding the foregoing, Landlord shall have the right to contest any alleged violation in good faith, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by law. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply with the terms of any final order or judgmentPremises. Tenant shall comply with the rules and regulations of the Building attached as Exhibit B and such other reasonable rules and regulations adopted by Landlord from time to time. Tenant shall also cause its agents, contractors, subcontractors, employees, customers, and subtenants to comply with all rules and regulations. Landlord shall not knowingly discriminate against Tenant in Landlord's enforcement of the rules and regulations.to

Compliance with Laws; Use. The Tenant shall use the Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants of the Building or interferes with the operation of the Buildingpurpose. Tenant shall comply with all Lawsstatutes, codes, ordinances, orders, rules and regulations of any municipal or governmental entity whether in effect now or later, including without limitation, the Environmental, Health and Safety Laws (as defined in Exhibit F attached hereto) and the Americans with Disabilities ActAct (“Law(s)”), regarding the operation of Tenant's ’s business and the use, condition, configuration use and occupancy of the Premises, subject to Landlord’s delivery obligations as expressly set forth in this Lease. Without limiting the generality of the foregoing, and except as provided in Exhibit C attached hereto, Tenant shall be solely responsible for complying with all Laws that relate to operations of Tenant’s laboratory uses, within 10 Business Days after receiptand all Laws pertaining to equipment, installations and improvements used or required in connection with the operations of Tenant’s laboratory uses. Tenant shall provide Landlord comply with copies applicable laboratory practices, (including the use of safety equipment) and policies established by the Center for Disease Control and Prevention (the “CDC”), and Tenant’s use of the Premises shall not exceed applicable Biosafety Level 2 (“BSL-2”) requirements and protocols in effect with respect to Tenant’s use from time to time, and Tenant shall store, use and dispose of Hazardous Materials in compliance with all applicable Environmental, Health and Safety Laws. In addition, Tenant shall, at its sole cost and expense, promptly comply with any Laws that relate to the Base Building (defined below), but only to the extent such obligations are triggered by (i) any use of the Premises by Tenant (other than for general office use) to the extent that such use requires compliance work beyond the baseline condition described in Exhibit J attached hereto, as improved by the Base Building Work and the Initial Tenant Work; provided, however, that Tenant shall be responsible for the cost of any notices it receives regarding such compliance work with respect to items for which Tenant is responsible for the maintenance and repair under this Lease, and/or (ii) any Alterations (as defined in Section 8.01) in or about the Premises performed or requested by Tenant after the Term Commencement Date, provided that Landlord shall perform the Base Building Work and the Initial Tenant Work in a violation or alleged violation of any good and workmanlike manner and in compliance with all applicable Laws, including without limitation, the Environmental, Health and Safety Laws and the Americans with Disabilities Act. Except to the extent properly included in Expensesthe same are expressly set forth herein as obligations of Tenant, Landlord shall be responsible for the cost of correcting any violations of Title III compliance of the Americans with Disabilities Act (ADA) with respect to the Common Areas of the Building. Notwithstanding the foregoing, Landlord shall have the right to contest any alleged violation in good faith, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by law. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply with the terms of any final order or judgment. Tenant shall comply with the rules and regulations of the Base Building attached as Exhibit B and such other reasonable rules and regulations adopted by Landlord from time to time. Tenant shall also cause its agents, contractors, subcontractors, employees, customers, and subtenants to comply with all rules and regulations. Landlord shall not knowingly discriminate against Tenant in Landlord's enforcement of the rules and regulations.with

Compliance with Laws; Use. The Subleased Premises shall be used only for research and development, laboratory, administrative uses and all related legal uses, as permitted under the Permitted Use Master Lease and for no other use whatsoever. Tenant shall not use or permit approved by the use City of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's reasonable opinion, unreasonably disturbs South San Francisco and any other tenants of governmental entity having jurisdiction over the Building or interferes with Subleased Premises. Subtenant and its employees, agents, contractors and invitees (the operation of the Building. Tenant “Subtenant Controlled Parties”) shall comply with all Lawsstatutes, including the Americans with Disabilities Actcodes, regarding the operation of Tenant's business ordinances, orders, rules and the use, condition, configuration and occupancy of the Premises. Tenant, within 10 Business Days after receipt, shall provide Landlord with copies regulations of any notices it receives regarding a violation municipal or alleged violation of any Laws. Except to the extent properly included in Expenses, Landlord shall be responsible for the cost of correcting any violations of Title III of the Americans with Disabilities Act (ADA) with respect to the Common Areas of the Building. Notwithstanding the foregoing, Landlord shall have the right to contest any alleged violation in good faithgovernmental entity, including, without limitation, all applicable federal, state and local Laws or regulations governing protection of, or damage to the right environment, or the treatment, storage or disposal of hazardous materials (collectively referred to apply for and obtain a waiver or deferment as “Laws”), regarding the operation of compliance, the right to assert any and all defenses allowed by law Subtenant’s business and the right to appeal any decisions, judgments or rulings use and occupancy of the Subleased Premises. In addition to the fullest extent permitted by law. Landlordforegoing, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to Subtenant shall comply with the terms of Sections 5.3 and 11 of the Master Lease, which are incorporated herein by this reference (provided, however, that all references therein to “Landlord” shall mean and refer to Master Landlord, except for any final order or judgment. Tenant indemnity obligations thereunder, which shall comply with be for the benefit of both Sublandlord and Master Landlord, and references to “Tenant” and “Premises” shall mean “Subtenant” and the “Subleased Premises”, respectively), and any other rules and regulations of the Building attached as Exhibit B and such other reasonable rules and regulations Master Premises adopted by Master Landlord from time to time. Tenant shall also cause its agents, contractorsprovided that a copy thereof is made available to Subtenant; provided, subcontractorshowever, employees, customers, and subtenants to comply with all rules and regulations. Landlord that Subtenant shall not knowingly discriminate against Tenant in Landlord's enforcement be required to perform any alteration, addition or change of the rules and regulationsSubleased Premises required by law, regulation, ordinance or order of any public authority unless such alteration, addition or change is required as a result of (i) Subtenant’s particular use of the Subleased Premises, (ii) any alteration to the Subleased Premises made by or on behalf of Subtenant, and/or (iii) any applications made by or on behalf of Subtenant for governmental permits, licenses or approvals.

Compliance with Laws; Use. The Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's ’s reasonable opinion, unreasonably disturbs any other tenants of the Building or the Project or interferes with the operation of the BuildingBuilding or the Project. Tenant shall comply with all Laws, including the Americans with Disabilities Act, regarding the operation of Tenant's ’s business and the use, condition, configuration and occupancy of the Premises. In addition, Tenant shall, at its sole cost and expense, promptly comply with any Laws that relate to the “Base Building” (defined below), but only to the extent such obligations are triggered by Tenant’s use of the Premises, other than for general office use, or Alterations or improvements in the Premises performed or requested by Tenant. Except to the extent that (i) Tenant is responsible for complying with Laws that relate to the Base Building as provided above, or (ii) changes to the Base Building are required due to the negligent or willful acts or omissions of Tenant, within 10 Business Days its agents, employees or contractors (other than the mere discovery of the violation), Landlord shall be responsible for correcting violations of any Laws existing as of the date of this Lease and Laws that first come into effect after receiptthe date of this Lease with respect to the Base Building located in the Building, provided that the cost of such compliance incurred after the Commencement Date shall be included in Expenses to the extent permitted in Exhibit E attached hereto. Tenant shall promptly provide Landlord with copies of any notices it receives regarding a violation or an alleged violation of Law; provided, however, if Tenant receives any Laws. Except to the extent properly included in Expenses, Landlord shall be responsible for the cost notice of correcting any violations violation of Title III of the Americans with Disabilities Act (ADA) Laws with respect to the Common Areas Base Building, Tenant shall, within five (5) business days after receipt thereof, provide Landlord with copies of the Buildingany such notices it receives with respect to such violation. Notwithstanding the foregoing, Landlord shall have the right to contest any alleged violation in good faith, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law Law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by lawLaw. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply with the terms of any final order or judgment. “Base Building” shall include the structural portions of the Building, the public restrooms and the Building mechanical, electrical and plumbing systems and equipment located in the internal core of the Building on the floor or floors on which the Premises are located. Tenant, within ten (10) days after receipt, shall provide Landlord with copies of any notices it receives regarding a violation or alleged violation of any Laws. Tenant shall comply with the rules and regulations of the Building attached as Exhibit B and such other reasonable rules and regulations adopted by Landlord from time to timetime and provided to Tenant in writing. Tenant shall also cause its agents, contractors, subcontractors, employees, customers, invitees and subtenants (each a “Tenant Entity” and collectively, the “Tenant Entities”) to comply with all rules and regulations. Landlord shall not knowingly discriminate against Tenant in Landlord's ’s adoption and enforcement of the rules and regulations.

Compliance with Laws; Use. The Premises shall be used only for the Permitted Use and for no other use whatsoeverwhatsoever without Landlord’s prior written consent. Tenant shall not use or permit the use of the Premises for any purpose which is illegalExcept as otherwise provided in this Lease, dangerous to persons or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants of the Building or interferes with the operation of the Building. Tenant shall comply with all Lawsstatutes, codes, ordinances, orders, rules and regulations of any municipal or governmental entity whether in effect now or later, including the Americans with Disabilities ActAct (“Law(s)”), regarding the operation of Tenant's business and ’s business, the use, condition, configuration and occupancy of the Premises and the Building systems located in or exclusively serving the Premises. TenantLandlord shall be responsible, within 10 Business Days after receipt, shall provide Landlord with copies of any notices it receives regarding a violation or alleged violation of any Laws. Except at its cost (except to the extent properly included in Expenses), Landlord shall be responsible for the cost of correcting any violations of Title III of the Americans with Disabilities Act (ADA) Laws with respect to the Common Areas of the BuildingBuilding and related to any Base Building systems (to the extent such obligations are not triggered by Tenant’s use of the Premises, any Alterations made by or for the benefit of Tenant, any “assembly occupancy” of the Premises by Tenant, any beach of Tenant’s obligations under this Lease, and except for any obligations specifically imposed upon Tenant pursuant to this Lease). Notwithstanding the foregoing, Landlord shall have the right to contest any alleged violation in good faith, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law Law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by lawLaw. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply with the terms of any final order or judgment. In addition, Tenant shall shall, at its sole cost and expense, promptly comply with any Laws that relate to the rules and regulations “Base Building” (defined below), but only to the extent such obligations are triggered by Tenant’s use of the Building attached as Exhibit B and such Premises, other reasonable rules and regulations adopted than for general office use, or Alterations or improvements in the Premises performed or requested by Landlord from time to timeTenant. Tenant shall also cause its agents, contractors, subcontractors, employees, customers, and subtenants to comply with all rules and regulations. Landlord shall not knowingly discriminate against Tenant in Landlord's enforcement of the rules and regulations.“

Compliance with Laws; Use. The Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants of the Building or interferes with the operation of the Building. Tenant shall comply with all statutes, codes, ordinances, orders, rules and regulations of any municipal or governmental entity (collectively, “Laws, including the Americans with Disabilities Act”), regarding the operation of Tenant's ’s business and the use, condition, configuration and occupancy of the Premises. Tenant, within 10 Business Days after receipt, shall provide Landlord with copies of any notices it receives regarding a violation or alleged violation of any Laws. Except to the extent properly included in Expenses, Landlord shall be responsible for the cost of correcting any violations of Title III of the Americans with Disabilities Act (ADA) with respect to the Common Areas of the Building. Notwithstanding the foregoing, Landlord shall have the right to contest any alleged violation in good faith, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by law. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply with the terms of any final order or judgment. Tenant shall comply with the rules Rules and regulations Regulations of the Building Development attached hereto as Exhibit B D and such other reasonable rules and regulations adopted by Landlord from time to time. In addition, Tenant shall also cause its agents, contractors, subcontractors, employees, customers, and subtenants to comply with all rules covenants, conditions and regulationsrestrictions in effect from time to time with respect to the Development, including, as listed in Exhibit F attached hereto. Landlord Furthermore, as part of its obligations hereunder, from and after the Commencement Date, Tenant shall, at its sole cost and expense, observe and comply with the provisions of Title III of the Americans with Disabilities Act of 1990, as amended and any regulations promulgated pursuant thereto (collectively, the “ADA”), as it pertains to Tenant’s use, occupancy, improvement and alteration of the Premises. Tenant shall not knowingly discriminate against use or allow the Premises to be used for any improper, immoral, unlawful or reasonably objectionable purpose, provided that Landlord understands and acknowledges that Tenant’s activities sometimes include simulated surgical procedures using human tissue and/or portions of human cadavers. Provided Tenant conducts such activities in Landlord's enforcement a discreet and respectful manner that does not disturb other Building tenants, and in compliance with all applicable laws, rules, regulations, codes and the like, Landlord acknowledges that such activities are not reasonably objectionable. Tenant shall not do or permit to be done anything which will obstruct or interfere with the rights of other tenants or occupants of the rules and regulationsDevelopment, or injure or annoy them. Tenant shall not cause, maintain or permit any nuisance in, on or about the Premises or the Development, nor commit or suffer to be committed any waste in, on or about the Premises.

Compliance with Laws; Use. The Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants of the Building or interferes with the operation of the Buildingproperty. Tenant shall comply with all Laws, including the Americans with Disabilities Act, regarding the operation of Tenant's ’s business and the use, condition, configuration and occupancy of the Premises. Tenant, within 10 Business Days 30 days after receipt, shall provide Landlord with copies of any notices it receives regarding a violation or alleged violation of any Laws. Except Tenant shall not cause or permit the storage, release or disposal of any hazardous substances, wastes or materials, or any medical, special or infectious wastes (other than storage, use and disposal in the ordinary course of business in accordance with all applicable laws), on or about the Premises or the Buildings of which they are a part and Tenant shall be solely responsible for and shall promptly pay the cost of removing from the Premises all such hazardous substances, wastes and materials and any such medical, special and infectious waste placed on the Premises by Tenant, which removal shall be in accordance with all applicable Laws. Landlord shall be solely responsible for and shall promptly pay the cost of (i) removing from the Premises and remediation of all such hazardous substances, wastes and materials and any such medical, special and infectious waste that was present on the Premises prior to the Commencement Date to the extent properly included required by applicable Laws, which removal shall be at such time as may be required by applicable Laws and otherwise in Expensesaccordance with all applicable Laws, and (ii) restoring the Premises to substantially the same condition as existed immediately prior to such removal and remediation; provided, however, that Landlord shall not be required to remove, and Tenant shall be responsible for the cost disposal of, hazardous substances, wastes and materials that are currently or have been disposed of correcting any violations in the ordinary course of Title III business in the operation of the Americans a hospital facility, consistent with Disabilities Act (ADA) with respect to the Common Areas hospitals of the Buildingsimilar size, and Landlord’s past practice and applicable Laws. Notwithstanding the foregoingHazardous substances, Landlord wastes or materials shall have the right to contest any alleged violation include asbestos and those which are defined in good faithapplicable Laws, including, without limitationincluding but not limited to, the right Comprehensive Environmental Response, Compensation and Liability Act of 1980, as amended, 42 USC Section 9601 et seq; the Resource Conservation and Recovery Act, as amended, 42 USC Section 6901 et seq; the Toxic Substance Control Act, as amended 15 USC Section 2601. Medical, special or infectious wastes shall include those which are defined pursuant to apply for and obtain a waiver or deferment of compliance, applicable medical waste Laws. To the right to assert any and all defenses allowed by law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by law. , Xxxxxxxx shall indemnify, defend and hold Tenant harmless from and against any claims or liability arising out of or connected with Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary ’s failure to comply with the terms of any final order Section V, which indemnification obligation shall survive the expiration or judgmentearlier termination of this Lease. Tenant shall comply with all applicable Laws which govern the rules use, storage handling and regulations disposal of the Building attached as Exhibit B hazardous substances, wastes or materials and such other reasonable rules and regulations adopted by Landlord from time to timemedical, special or infectious wastes. Tenant shall also cause its agentsindemnify, contractors, subcontractors, employees, customers, defend and subtenants hold Landlord harmless from and against any claims or liability arising out of or connected with Xxxxxx’s failure to comply with all rules and regulationsthe terms of Section V, which indemnification obligation shall survive the expiration or earlier termination of this Lease. Landlord In no event shall not knowingly discriminate against such indemnification obligation of Tenant apply to any claims, loss, damage, events, acts or omissions occurring prior to the Commencement Date. Nothing herein will prohibit the use of hazardous substances in Landlord's enforcement non-significant quantities in the ordinary course of the rules and regulationsbusiness consistent with applicable Laws.

Compliance with Laws; Use. The Tenant shall use the Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants of the Building or interferes with the operation of the Buildingpurpose. Tenant shall comply with all Lawsstatutes, codes, ordinances, orders, rules and regulations of any municipal or governmental entity whether in effect now or later, including without limitation, the Environmental Health and Safety Laws (as defined in Exhibit F attached hereto) and the Americans with Disabilities ActAct (“Law(s)”), regarding the operation of Tenant's ’s business and the use, condition, configuration use and occupancy of the Premises, subject to Landlord’s delivery obligations as expressly set forth in this Lease. Tenant, within 10 Business Days after receipt, shall provide Landlord with copies Without limiting the generality of any notices it receives regarding a violation or alleged violation of any Laws. Except to the extent properly included in Expenses, Landlord shall be responsible for the cost of correcting any violations of Title III of the Americans with Disabilities Act (ADA) with respect to the Common Areas of the Building. Notwithstanding the foregoing, and except as provided in Exhibit C attached hereto, Tenant shall be solely responsible for complying with all Laws that relate to operations of Tenant’s laboratory and vivarium uses, and all Laws pertaining to equipment, installations and improvements used or required in connection with the operations of Tenant’s laboratory and vivarium uses. Tenant acknowledges and agrees that the vivarium constitutes an “Add Alternate Item” above and beyond the “Xxxxxx Spec Plan” (as such terms are defined in Exhibit C) and shall be installed at Tenant’s sole cost and expense as further discussed in Exhibit C. The vivarium will be permitted to be operated in the portion of the Premises shown on plans submitted by Tenant and approved by Landlord in accordance with Exhibit C attached hereto (the “Permitted Vivarium Area”), and shall be used for biomedical research, development, handling and testing of the Permitted Animals (as hereinafter defined) (the “Animal Use”). Tenant shall not use any animals other than mice and rats (the “Permitted Animals”) in its operations. The movement of any Permitted Animals into or out of the Premises shall occur only outside of Building Service Hours. In addition, Tenant shall take any reasonable actions necessary to resolve any picketing or public relations issues arising from the Animal Use, and shall have the right to contest any alleged violation in good faith, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law and the right to appeal any decisions, judgments or rulings pickets removed. The Animal Use shall be permitted subject to the fullest extent following: (i) all research, development, handling and testing of the Permitted Animals shall be conducted in strict compliance with all applicable Laws and with good scientific and medical practice; (ii) all dead animals, any part thereof or any waste products related thereto, shall be disposed of, at Tenant’s sole cost and expense, in strict compliance with all applicable Laws and with good scientific and medical practice; (iii) no odors, noises or any similar nuisance shall be permitted by law. Landlord, after to emanate from or permeate outside the exhaustion Premises; and (iv) Tenant’s use of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply the vivarium shall not interfere with the terms peaceable and quiet use and enjoyment by other tenants or occupants of the Industrial Park. Tenant shall procure and deliver to Landlord copies of all necessary permits and approvals necessary for the use and operation of the vivarium before allowing any final order or judgmentactual Permitted Animals onto the Premises and shall maintain such permits and approvals during the Term. Tenant shall comply with applicable laboratory practices, (including the rules use of safety equipment) and regulations policies established by the Center for Disease Control and Prevention (the “CDC”), and Tenant’s use of the Building attached as Exhibit B Premises shall not exceed applicable Biosafety Level 2 (“BSL-2”) requirements and such other reasonable rules and regulations adopted by Landlord protocols in effect with respect to Tenant’s use from time to time. , and Tenant shall also cause its agentsstore, contractors, subcontractors, employees, customers, use and subtenants to comply dispose of Hazardous Materials in compliance with all rules applicable Environmental, Health and regulations. Landlord shall not knowingly discriminate against Tenant in Landlord's enforcement of the rules and regulationsSafety Laws.

Compliance with Laws; Use. The Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use comply, and shall cause all of the Premises for any purpose which is illegalTenant Related Parties to comply, dangerous to persons or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants of the Building or interferes with the operation of the Building. Tenant shall comply with all Lawslaws, including statutes, codes, ordinances, orders, rules and regulations of any municipal or governmental entity whether in effect now or later, including, without limitation, the Americans with Disabilities ActAct (“Law(s)”), regarding the operation of Tenant's ’s business and the use, condition, configuration and occupancy of the Premises. In addition, Tenant shall, at its sole cost and expense, promptly comply with any Laws that relate to the Common Areas and other portions of the Property, other than the Premises, but only to the extent such obligations are triggered by Tenant’s specific use of the Premises or such Common Areas, or Alterations or improvements in the Premises or such Common Areas, performed or requested by Tenant or Tenant’s obligations as an employer or the negligence or willful misconduct of any of the Tenant Related Parties (“Tenant Triggered Compliance”). Notwithstanding the foregoing, Tenant shall notify Landlord prior to commencing any Tenant Triggered Compliance. With respect to any Tenant Triggered Compliance specifically pertaining to the structure of the Building and the common systems (“Common Systems”) of the Building (as opposed to portions of the systems which would exclusively serve a specific premises if the Building was a multi-tenant building), Landlord may elect, by written notice to Tenant within 10 Business Days days after receiptreceipt of Tenant’s notice, to perform any such Tenant Triggered Compliance, at Tenant’s sole cost and expense. Tenant shall promptly provide Landlord with copies of any notices it receives regarding a violation or an alleged violation of any Law. Tenant shall not exceed the density limit for the Building, as provided under applicable Laws. Except , provided to the extent properly included in Expensesthe mechanical, Landlord shall be responsible for the cost of correcting any violations of Title III plumbing and electrical systems of the Americans with Disabilities Act (ADA) with respect Building as of the Effective Date are not sufficient to provide the services described in Article 7 to the Common Areas density of its employees and equipment desired by Tenant, Tenant, at its sole expense, shall perform Alterations (defined in Section 9.03) to such systems of the Building. Notwithstanding the foregoing, Landlord and shall have the right thereafter repair, maintain and replace such Alterations, in order to contest any alleged violation in good faith, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by law. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply with the terms of any final order or judgmentprovide sufficient services. Tenant shall comply (and cause the Tenant Related Parties and their respective contractors and vendors to comply) with the rules and regulations of the Building attached as Exhibit B E and such other reasonable commercially reasonable, non-discriminatory rules and regulations adopted by Landlord from time to time. Tenant shall also cause its agents, contractors, subcontractors, employees, customers, and subtenants to comply with all including rules and regulations. Landlord shall not knowingly discriminate against Tenant in Landlord's enforcement regulations for the performance of the rules and regulationsAlterations.

Compliance with Laws; Use. The Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's ’s reasonable opinion, unreasonably disturbs any other tenants of the Building or the Property or interferes with the operation of the BuildingBuilding or the Property. Tenant shall not permit any odors, smoke, dust, gas, substances, noise or vibrations to emanate from the Premises or from any portion of the Common Areas as a result of the use by Tenant or any Tenant Related Party thereof. Storage outside the Premises of materials, vehicles or any other items is prohibited. Tenant shall not use or allow the Premises to be used for any immoral, improper or unlawful purpose, nor shall Tenant cause or maintain or permit any nuisance in, on or about the Premises. Tenant shall not commit or suffer the commission of any waste in, on or about the Premises. Tenant shall not allow any sale by auction upon the Premises, or place any loads upon the floors, walls or ceilings which could endanger the structure, or place any harmful substances in the drainage system of the Building or Property. No waste, materials or refuse shall be dumped upon or permitted to remain outside the Premises except in trash containers place inside exterior enclosures designated for that purpose by Landlord. The Premises shall be used for the Permitted Use and for no other use whatsoever. Tenant shall comply with all Lawsstatutes, codes, ordinances, orders, rules and regulations of any municipal or governmental entity whether in effect now or later, including the Americans with Disabilities ActAct (“Law(s)”), regarding the operation of Tenant's ’s business and the use, condition, configuration and occupancy of the Premises. TenantIn addition, within 10 Business Days after receiptTenant shall, shall provide Landlord at its sole cost and expense, promptly comply with copies of any notices it receives regarding a violation or alleged violation of any Laws. Except Laws that relate to the “Base Building” (defined below), but only to the extent properly included in Expenses, Landlord shall be responsible for the cost of correcting any violations of Title III such obligations are triggered by Tenant’s use of the Americans with Disabilities Act (ADA) with respect to the Common Areas of the Building. Notwithstanding the foregoingPremises, Landlord shall have the right to contest any alleged violation in good faithother than for general office use, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by law. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations Alterations or improvements necessary to comply with in the terms of any final order Premises performed or judgmentrequested by Tenant. Tenant shall comply with the rules and regulations of the Building attached as Exhibit B and such other reasonable rules and regulations adopted by Landlord from time to time. Tenant shall also cause its agents, contractors, subcontractors, employees, customers, and subtenants to comply with all rules and regulations. Landlord shall not knowingly discriminate against Tenant in Landlord's enforcement of the rules and regulations.“

Compliance with Laws; Use. The Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's ’s reasonable opinion, unreasonably disturbs any other tenants of the Building or the Property or interferes with the operation of the BuildingBuilding or the Property. Tenant shall not permit any odors, smoke, dust, gas, substances, noise or vibrations to emanate from the Premises or from any portion of the Common Areas as a result of the use by Tenant or any Tenant Related Party thereof. Storage outside the Premises of materials, vehicles or any other items is prohibited. Tenant shall not use or allow the Premises to be used for any immoral, improper or unlawful purpose, nor shall Tenant cause or maintain or permit any nuisance in, on or about the Premises. Tenant shall not commit or suffer the commission of any waste in, on or about the Premises. Tenant shall not allow any sale by auction upon the Premises, or place any loads upon the floors, walls or ceilings which could endanger the structure, or place any harmful substances in the drainage system of the Building or Property. No waste, materials or refuse shall be dumped upon or permitted to remain outside the Premises except in trash containers placed inside exterior enclosures designated for that purpose by Landlord. The Premises shall be used for the Permitted Use and for no other use whatsoever. Tenant shall comply with all Lawsstatutes, codes, ordinances, orders, rules and regulations of any municipal or governmental entity whether in effect now or later, including the Americans with Disabilities ActAct (“Law(s)”), regarding the operation of Tenant's ’s business and the use, condition, configuration and occupancy of the Premises. TenantIn addition, within 10 Business Days after receiptTenant shall, shall provide Landlord at its sole cost and expense, promptly comply with copies of any notices it receives regarding a violation or alleged violation of any Laws. Except Laws that relate to the “Base Building” (defined below), but only to the extent properly included in Expenses, Landlord shall be responsible for the cost of correcting any violations of Title III such obligations are triggered by Tenant’s use of the Americans with Disabilities Act (ADA) with respect to the Common Areas of the Building. Notwithstanding the foregoingPremises, Landlord shall have the right to contest any alleged violation in good faithother than for general office use, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by law. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations Alterations or improvements necessary to comply with in the terms of any final order Premises performed or judgmentrequested by Tenant. Tenant shall comply with the rules and regulations of the Building attached as Exhibit B and such other reasonable rules and regulations adopted by Landlord from time to time. Tenant shall also cause its agents, contractors, subcontractors, employees, customers, and subtenants to comply with all rules and regulations. Landlord shall not knowingly discriminate against Tenant in Landlord's enforcement of the rules and regulations.“

Compliance with Laws; Use. The Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants of the Building or interferes with the operation of the Building. Tenant shall comply with all Laws, including the Americans with Disabilities Act, regarding the operation of Tenant's business and the use, condition, configuration and occupancy of the Premises. Tenant, within 10 Business Days after receipt, shall provide Landlord with copies of any notices it receives regarding a violation or alleged violation of any Laws. Except to the extent properly included in Expenses, Landlord shall be responsible for the cost of correcting any violations of Title III of the Americans with Disabilities Act (ADA) with respect to the Common Areas of the Building. Notwithstanding the foregoing, Landlord shall have the right to contest any alleged violation in good faith, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law Law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by lawLaw. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply with the terms of any final order or judgment. Tenant, within 10 days after receipt, shall provide Landlord with copies of any notices it receives regarding a violation or alleged violation of any Laws. Tenant shall comply with the rules and regulations of the Building attached as Exhibit B and such other reasonable rules and regulations adopted by Landlord from time to time. Tenant shall also cause its agents, contractors, subcontractors, employees, customers, and subtenants to comply with all rules and regulations. Landlord shall not knowingly discriminate against Tenant in Landlord's enforcement of the rules and regulations.

Compliance with Laws; Use. The Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants of the Building Buildings or interferes with the operation of the BuildingBuildings. Subject to Landlord's obligation to complete Landlord Work in compliance with Laws, Tenant shall comply with all Laws, including the Americans with Disabilities Act, regarding the operation of Tenant's business and the use, condition, configuration and occupancy of the PremisesPremises during the Term. Tenant, within 10 Business Days days after receipt, shall provide Landlord with copies of any notices it receives regarding a violation or alleged violation of any LawsLaws by Tenant on the Property. Except Landlord, at its sole cost and expense (except to the extent properly included in Expenses), Landlord shall be responsible for the cost of correcting any violations of Title III of the Americans with Disabilities Act (ADA) Laws with respect to the Premises and the Building Common Areas Areas, provided that Landlord's obligation with respect to the Premises shall be limited to violations that arise out of the Buildingcondition of the Premises on the Commencement Date and prior to the installation of any furniture, equipment and other personal property of Tenant. Notwithstanding the foregoing, Landlord or Tenant shall have the right to contest any alleged violation in good faith, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by law. LandlordLandlord or Tenant, as obligated herein, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply with the terms of any final order or judgment. Notwithstanding the foregoing, Tenant, not Landlord, shall be responsible for the correction of any violation of Laws that arise out of or in connection with the specific nature of Tenant's business in the Premises (other than general office use), the acts or omissions of Tenant, its agents, employees or contractors not otherwise permitted herein, Tenant's arrangement of any furniture, equipment or other property in the Premises, any repairs, alterations, additions or improvements performed by or on behalf of Tenant and any design or configuration of the Premises specifically requested by Tenant. Tenant shall comply with the rules and regulations of the Building Buildings attached as Exhibit B and such other reasonable rules and regulations adopted by Landlord from time to time; subject to the provisions of Articles VII, XVII and XVIII below, Tenant will have access to the Premises and Buildings twenty-four (24) hours per day, seven (7) days per week, via a card reader system. Tenant shall also cause its agents, contractors, subcontractors, employees, customers, and subtenants to comply with all rules and regulations. Landlord shall not knowingly discriminate against Tenant in Landlord's enforcement of the rules and regulations.

Compliance with Laws; Use. A. The Premises shall may only be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants of the Building or interferes with the operation of the Building. Tenant shall comply with all Laws, including the Americans with Disabilities Act, regarding the operation of Tenant's business and the use, condition, configuration and occupancy of the Premises. Premises provided that Landlord shall be responsible for performing the ADA Modifications and the Bridge Modifications as provided in the Work Letter attached hereto as EXHIBIT D. Tenant, within 10 Business Days days after receipt, shall provide Landlord with copies of any notices it receives regarding a violation or alleged violation of any Laws. Except to the extent properly included in Expenses, Landlord shall be responsible for the cost of correcting any violations of Title III of the Americans with Disabilities Act (ADA) and other Laws with respect to the Common Areas of the BuildingBuilding (including but not limited to ADA issues regarding the path of travel in the Common Areas). Notwithstanding the foregoing, Landlord shall have the right to contest any alleged violation in good faith, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by law. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply with the terms of any final order or judgment. Tenant shall comply with the rules and regulations of the Building attached as Exhibit EXHIBIT B and such other reasonable rules and regulations adopted by Landlord from time to time. Tenant shall also cause its agents, contractors, subcontractors, employees, customers, and subtenants to comply with all rules and regulations. Landlord shall not knowingly discriminate against Tenant in Landlord's enforcement of the rules and regulations.

Compliance with Laws; Use. The Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use comply, and shall cause all of the Premises for any purpose which is illegalTenant Related Parties to comply, dangerous to persons or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants of the Building or interferes with the operation of the Building. Tenant shall comply with all Lawslaws, including statutes, codes, ordinances, orders, rules and regulations of any municipal or governmental entity whether in effect now or later, including, without limitation, the Americans with Disabilities ActAct (“Law(s)”), regarding the operation of Tenant's ’s business and the use, condition, configuration and occupancy of the Premises. In addition, Tenant shall, at its sole cost, promptly comply with any Laws that relate to the Common Areas and other portions of the Property, other than the Premises, but only to the extent such obligations are triggered by Tenant’s specific use of the Premises, or Alterations or improvements in the Premises performed or requested by Tenant, or Tenant’s obligations as an employer, or the breach of any of Tenant’s obligations under this Lease, or the negligence or willful misconduct of Tenant or any of the Tenant Related Parties (“Tenant Triggered Compliance”). Notwithstanding the foregoing, Tenant shall notify Landlord prior to commencing any Tenant Triggered Compliance and Landlord may elect, by written notice to Tenant within 10 Business Days days after receiptreceipt of Tenant’s notice, to perform any such Tenant Triggered Compliance, at Tenant’s sole cost. Tenant shall promptly provide Landlord with copies of any notices it receives regarding a violation or an alleged violation of any LawsLaw. Except Notwithstanding anything to the extent properly included contrary contained in Expensesthis Lease, Landlord Tenant shall be responsible limit the number of work seats in the Premises at any time in such a manner as to not exceed a ratio of one work seat for the cost of correcting any violations of Title III each 167 rentable square feet of the Americans with Disabilities Act (ADA) with respect Premises, Tenant acknowledging that the number of work seats per rentable square foot of the Premises has a material effect on Landlord’s ability to provide the HVAC, electrical, elevator and other services set forth in this Lease. If any upgrade to the Common Areas of Building standard systems, including but not limited to the Building. Notwithstanding the foregoing's mechanical and electrical systems and restroom fixtures, Landlord shall have the right to contest any alleged violation in good faith, including, without limitation, the right to apply for and obtain a waiver or deferment is necessary by reason of compliance, the right to assert any and all defenses allowed by law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by law. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary Tenant's failure to comply with the terms of any final order or judgmentsuch occupancy density requirements, as reasonably determined by Landlord, to accommodate Tenant's needs, and Tenant fails to cure such failure within ten (10) days after notice from Landlord, Tenant will reimburse Landlord promptly upon Landlord's demand for all costs incurred by Landlord in connection with such upgrade. Tenant shall comply (and cause the Tenant Related Parties and their respective contractors and vendors to comply) with the rules and regulations of the Building attached as Exhibit B E and such other reasonable rules and regulations adopted by Landlord from time to time. Tenant shall also cause its agents, contractors, subcontractors, employees, customers, and subtenants to comply with all including rules and regulations. Landlord shall not knowingly discriminate against Tenant regulations for the performance of Alterations (defined in Landlord's enforcement of the rules and regulationsSection 9.03).

Compliance with Laws; Use. The Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants of the Building or interferes with the operation of the Building. Tenant shall comply with all Laws, including the Americans with Disabilities Act, regarding the operation of Tenant's business and the use, condition, configuration and occupancy of the Premises. TenantLandlord, within 10 Business Days after receipt, shall provide Landlord with copies of any notices it receives regarding a violation or alleged violation of any Laws. Except at its sole cost and expense (except to the extent properly included in Expenses), Landlord shall be responsible for the cost of correcting any violations of Title III of the Americans with Disabilities Act (ADA) with respect to the Premises and the Common Areas of the Building, provided that Landlord's obligation with respect to the Premises shall be limited to violations that arise out of the Landlord Work and/or the condition of the Premises prior to the installation of any furniture, equipment and other personal property of Tenant subsequent to the date of this Lease. Notwithstanding the foregoing, Landlord shall have the right to contest any alleged violation in good faith, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law Law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by lawLaw. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply with the terms of any final order or judgment. Notwithstanding the foregoing, Tenant, not Landlord, shall be responsible for the correction of any violations that arise out of or in connection with any claims brought under any provision of the Americans with Disabilities Act other than Title III, the specific nature of Tenant's business in the Premises (other than general office use), the acts or omissions of Tenant, its agents, employees or contractors, Tenant's arrangement of any furniture, equipment or other property in the Premises, any repairs, alterations, additions or improvements performed by or on behalf of Tenant (other than the Landlord Work) and any design or configuration of the Premises specifically requested by Tenant after being informed that such design or configuration may not be in strict compliance with the ADA. Tenant, within 10 days after receipt, shall provide Landlord with copies of any notices it receives regarding a violation or alleged violation of any Laws. Tenant shall comply with the rules and regulations of the Building attached as Exhibit B and such other reasonable rules and regulations adopted by Landlord from time to time. Tenant shall also cause its agents, contractors, subcontractors, employees, customers, and subtenants to comply with all rules and regulations. Landlord shall not knowingly discriminate against Tenant in Landlord's enforcement of the rules and regulations. The rules and regulations shall be generally applicable, and generally applied in the same manner, to all tenants of the Building. If there is a conflict between.this Lease and any rules and regulations enacted after the date of this Lease, the terms of this Lease shall control.

Compliance with Laws; Use. The Premises shall be used only for the Permitted Use and for no other use whatsoever. Notwithstanding the foregoing, one time during the Term of this Lease, Tenant shall not use or permit the use may submit to Landlord a request that a portion of the Premises for any purpose which (not to exceed 2,000 square feet) be used as a retail bank branch. Landlord shall not unreasonably withhold its consent to such modification to the Permitted Use, but may condition its consent on such requirements as Landlord may deem necessary to reflect such modification to the Permitted Use and the impact it may have on the Building and other tenants at the Property, including but not limited to a requirement that Tenant provide extra security, install certain additional leasehold improvements, and/or pay excess costs to reflect added wear and tear due to increased foot traffic at the Building. Without limitation, it is illegal, dangerous to persons or property or which, in agreed that Landlord's reasonable opinion, consent shall not be considered unreasonably disturbs any withheld if (i) such modification to the Permitted Use is not suitable for the Building considering the business of the other tenants or would result in a violation of another tenant's rights, (ii) Tenant is in default after the expiration of the notice and cure periods in this Lease, or (iii) any portion of the Building or interferes with Premises would likely become subject to additional or different Laws as a consequence of such proposed modification to the operation of Permitted Use. In the Buildingevent Landlord consents to such modification to the Permitted Use, Landlord and Tenant shall enter into an amendment to this Lease modifying the Permitted Use and addressing such other conditions as Landlord may deem necessary. Tenant shall comply with all Lawsstatutes, codes, ordinances, orders, rules and regulations of any municipal or governmental entity whether in effect now or later, including the Americans with Disabilities ActAct ("Law(s)"), regarding the operation of Tenant's business and the use, condition, configuration and occupancy of the Premises. TenantIn addition, within 10 Business Days after receiptTenant shall, shall provide Landlord at its sole cost and expense, promptly comply with copies of any notices it receives regarding a violation or alleged violation of any Laws. Except Laws that relate to the "Base Building" (defined below), but only to the extent properly included in Expenses, Landlord shall be responsible for the cost of correcting any violations of Title III such obligations are triggered by Tenant's use of the Americans with Disabilities Act (ADA) with respect to the Common Areas of the Building. Notwithstanding the foregoingPremises, Landlord shall have the right to contest any alleged violation in good faithother than for general office use, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by law. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations Alterations or improvements necessary to comply with in the terms of any final order Premises performed or judgmentrequested by Tenant. Tenant shall comply with the rules and regulations of the Building attached as Exhibit B and such other reasonable rules and regulations adopted by Landlord from time to time. Tenant shall also cause its agents, contractors, subcontractors, employees, customers, and subtenants to comply with all rules and regulations. Landlord shall not knowingly discriminate against Tenant in Landlord's enforcement of the rules and regulations."

Compliance with Laws; Use. The Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's ’s reasonable opinion, unreasonably disturbs any other tenants of the Building or interferes with the operation of the Building. Tenant shall comply with all Laws, including the Americans with Disabilities Act, regarding the operation of Tenant's ’s business and the use, condition, configuration and occupancy of the Premises. Notwithstanding the foregoing, Tenant shall not be obligated to make any structural alterations or capital improvements to the Premises to comply with any Laws unless such compliance is required as the result of the specific nature of Tenant’s business in the Premises (other than general office use) or is the result of the acts or omissions of Tenant or its agents, employees or contractors or any design or configuration of the Premises specifically installed by Tenant. Tenant, within 10 Business Days days after receipt, shall provide Landlord with copies of any notices it receives regarding a violation or alleged violation of any Laws. Except to the extent properly included in ExpensesTenant shall reimburse and compensate Landlord for all expenditures made by, or damages or fines sustained or incurred by, Landlord shall be responsible for the cost of correcting due to any violations of Title III of the Americans with Disabilities Act Laws by Tenant or any Tenant Related Parties (ADAas defined in Section 14.B hereof) with respect to the Common Areas of the Building. Notwithstanding the foregoing, Landlord shall have the right to contest any alleged violation in good faith, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by law. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply with the terms of any final order or judgmentPremises. Tenant shall comply with the rules and regulations of the Building attached as Exhibit B and such other reasonable rules and regulations adopted by Landlord from time to time. Tenant shall also cause its agents, contractors, subcontractors, employees, customers, employees and subtenants to comply with all rules and regulations. Landlord shall not knowingly discriminate against Tenant in Landlord's ’s enforcement of the rules and regulations.

Compliance with Laws; Use. The Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant In no event shall not use or permit the use of the Premises for any purpose which is illegalbe used as a co-working center, dangerous to persons executive office suites or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants of the Building or interferes with the operation of the Buildinga flexible workplace center. Tenant shall comply with all statutes, codes, ordinances, orders, rules and regulations of any municipal or governmental entity (collectively, "Laws, including the Americans with Disabilities Act"), regarding the operation of Tenant's business and the use, condition, configuration and occupancy of the Premises. TenantPursuant to Section 1938 of the California Civil Code, Landlord hereby advises Tenant that the Premises has not undergone an inspection by a certified access specialist (a “CASp”) and no representations are made with respect to compliance with accessibility standards. Further, pursuant to Section 1938 of the California Civil Code, Landlord notifies Tenant of the following: “A Certified Access Specialist (CASp) can inspect the subject premises and determine whether the subject premises comply with all of the applicable construction-related accessibility standards under state law. Although state law does not require a CASp inspection of the subject premises, the commercial property owner or lessor may not prohibit the lessee or tenant from obtaining a CASp inspection of the subject premises for the occupancy or potential occupancy of the lessee or tenant, if requested by the lessee or tenant. The parties shall mutually agree on the arrangements for the time and manner of the CASp inspection, the payment of the fee for the CASp inspection and the cost of making any repairs necessary to correct violations of construction-related accessibility standards within 10 Business Days after receiptthe premises.” Therefore and notwithstanding anything to the contrary contained in this Lease, Landlord and Tenant agree that (a) Tenant may, at its option and at its sole cost, cause a CASp to inspect the Premises and determine whether the Premises complies with all of the applicable construction-related accessibility standards under state law, (b) the parties shall provide Landlord with copies mutually coordinate and reasonably approve of the timing of any notices it receives regarding such CASp inspection so that Landlord may, at its option, have a violation or alleged violation of any Laws. Except to the extent properly included in Expensesrepresentative present during such inspection, Landlord and (c) Tenant shall be solely responsible for the cost of correcting making any repairs necessary to correct violations of Title III of construction-related accessibility standards within the Americans with Disabilities Act (ADA) with respect to the Common Areas of the Building. Notwithstanding the foregoing, Landlord shall have the right to contest any alleged violation in good faith, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by law. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply with the terms of any final order or judgmentPremises. Tenant shall comply with the rules Rules and regulations Regulations of the Building attached as Exhibit B D and such other commercially reasonable rules and regulations adopted by Landlord from time to time. Tenant shall also cause its agents, contractors, subcontractors, employees, customers, and subtenants time upon at least thirty (30) calendar days prior written notice to comply with all rules and regulationsTenant. Landlord shall not knowingly discriminate against Tenant modify and enforce the Rules and Regulations in Landlord's enforcement a uniform and non-discriminatory manner with respect to all tenants and occupants of the rules Project, and regulationsfurther provided any modification of the Rules and Regulations shall not materially increase Tenant’s obligations or be materially inconsistent with Tenant’s rights under this Lease.

Compliance with Laws; Use. The Subleased Premises shall be used only for research and development, administrative uses and all related legal uses, as approved by the Permitted Use City of South San Francisco and for no other use whatsoever. Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants governmental entity having jurisdiction over the Subleased Premises. In addition, Subtenant may use the Subleased Premises as a wet lab, subject to (a) the express written consent of Master Landlord, (b) Subtenant’s covenant in Section 3(c) hereof not to locate a wet lab above or adjacent to the Building or interferes with Server Room, and (c) all applicable Laws. Subtenant and its employees, agents, contractors and invitees (the operation of the Building. Tenant “Subtenant Controlled Parties”) shall comply with all Lawsstatutes, including the Americans with Disabilities Actcodes, regarding the operation of Tenant's business ordinances, orders, rules and the use, condition, configuration and occupancy of the Premises. Tenant, within 10 Business Days after receipt, shall provide Landlord with copies regulations of any notices it receives regarding a violation municipal or alleged violation of any Laws. Except to the extent properly included in Expenses, Landlord shall be responsible for the cost of correcting any violations of Title III of the Americans with Disabilities Act (ADA) with respect to the Common Areas of the Building. Notwithstanding the foregoing, Landlord shall have the right to contest any alleged violation in good faithgovernmental entity, including, without limitation, the right to apply for all applicable federal, state and obtain a waiver local Laws or deferment of complianceregulations governing protection of, the right to assert any and all defenses allowed by law and the right to appeal any decisions, judgments or rulings damage to the fullest extent permitted by lawenvironment, or the treatment, storage or disposal of hazardous materials (collectively referred to as “Laws”), regarding the operation of Subtenant’s business and Subtenant’s particular use of the Subleased Premises. LandlordIn addition to the foregoing, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to Subtenant shall comply with the terms of Sections 7 and 30 and Exhibits E and G of the Master Lease (as modified by the Master Landlord’s Consent), which are incorporated herein by this reference (provided, however, that all references therein to “Landlord” shall mean and refer to Master Landlord, except for any final order or judgment. Tenant indemnity obligations thereunder, which shall comply with be for the benefit of both Sublandlord and Master Landlord, and references to “Tenant” and “Premises” shall mean “Subtenant” and the “Subleased Premises”, respectively), and any other rules and regulations of the Building attached as Exhibit B and such other reasonable rules and regulations adopted by Master Landlord from time to time. Tenant shall also cause its agents, contractors, subcontractors, employees, customers, and subtenants provided that a copy thereof is made available to comply with all rules and regulations. Landlord shall not knowingly discriminate against Tenant in Landlord's enforcement of the rules and regulationsSubtenant.

Compliance with Laws; Use. The Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants of the Building or interferes with the operation of the Building. Tenant shall comply with all Lawsstatutes, codes, ordinances, orders, rules and regulations of any municipal or governmental entity whether in effect now or later, including the Americans with Disabilities ActAct (“Law(s)”), regarding the operation of Tenant's ’s business and the use, condition, configuration and occupancy of the Premises. In addition, Tenant shall, at its sole cost and expense, promptly comply with any Laws that relate to the “Base Building” (defined below), but only to the extent such obligations are triggered by Tenant’s use of the Premises, other than for general, office use, or Alterations or improvements in the Premises performed or requested by Tenant, within 10 Business Days after receipt“Base Building” shall include the structural portions of the Building, the public restrooms and the Building mechanical, electrical and plumbing systems and equipment located in the internal core of the Building on the floor or floors on which the Premises are located. Tenant shall promptly provide Landlord with copies of any notices it receives regarding a violation or an alleged violation of any Laws. Except to the extent properly included in Expenses, Landlord shall be responsible for the cost of correcting any violations of Title III of the Americans with Disabilities Act (ADA) with respect to the Common Areas of the Building. Notwithstanding the foregoing, Landlord shall have the right to contest any alleged violation in good faith, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by law. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply with the terms of any final order or judgmentLaw. Tenant shall comply with the rules and regulations of the Building attached as Exhibit B E and such other reasonable rules and regulations adopted by Landlord from time to time, including rules and regulations for the performance of Alterations (defined in Section 9). Nothing herein shall require Tenant shall also cause its agentsto perform any alterations, contractors, subcontractors, employees, customers, and subtenants additions or improvements which are necessary to comply with all rules Laws with respect to the Common Areas, unless such, compliance relates to the Common Areas on any floor on which the Premises are located and regulationsarises directly out of the performance of work by or on behalf of Tenant in the Premises or Tenant’s use of the Premises for purposes other than general office use. Landlord shall not knowingly discriminate against Tenant will, at Landlord’s expense (except to the extent properly included in Landlord's enforcement of Expenses), perform all acts required to comply with such Laws with respect to the rules foregoing as the same affect the Premises and regulationsthe Building.

Compliance with Laws; Use. The Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants of the Building or interferes with the operation of the Building. Tenant shall comply with all Lawsstatutes, codes, ordinances, orders, rules and regulations of any municipal or governmental entity whether in effect now or later, including the Americans with Disabilities ActAct ("LAW(S)"), regarding the operation of Tenant's business and the use, condition, configuration and occupancy of the Premises. In addition, Tenant shall, at its sole cost and expense, promptly comply with any Laws that relate to the "Base Building" (defined below), but only to the extent such obligations are triggered by Tenant's use of the Premises, within 10 Business Days after receiptother than for general office use (or, with respect to the Lab Space, any other Permitted Use), or Alterations or improvements in the Premises performed or requested by Tenant. "BASE BUILDING" shall provide Landlord with copies include the structural portions of any notices it receives regarding a violation the Buildings, the public restrooms and the Buildings mechanical, electrical and plumbing systems and equipment located in the internal core of the Buildings on the floor or alleged violation of any Lawsfloors on which the Premises are located. Except to the extent properly included in Expenses, Landlord shall be responsible for the cost of correcting any violations of Title III of the Americans with Disabilities Act (ADA) with respect to the Common Areas of the BuildingBuildings. Landlord shall comply with all other Laws relating to the Common Areas of the Buildings, provided that compliance with such Laws is not the responsibility of Tenant under this Lease, and provided further that Landlord's failure to comply therewith would prohibit Tenant from obtaining or maintaining a certificate of occupancy, or its equivalent, for the Premises, or would unreasonably and materially affect the safety of Tenant's employees or create a significant health hazard for Tenant's employees. Notwithstanding the foregoing, Landlord shall have the right to contest any alleged violation in good faith, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law Law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by lawLaw. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply with the terms of any final order or judgment. Tenant shall promptly provide Landlord with copies of any notices it receives regarding an alleged violation of Law. Tenant shall reimburse and compensate Landlord for all expenditures made by, or damages or fines sustained by, Landlord due to any violations of Laws by Tenant or any Tenant Related Parties with respect to the Premises. Tenant shall comply with the rules and regulations of the Building Buildings attached as Exhibit B EXHIBIT D and such other reasonable rules and regulations adopted by Landlord from time to time, including rules and regulations for the performance of Alterations (defined in Section 9). Tenant shall also cause its agents, contractors, subcontractors, employees, customers, obtain and subtenants pay for all permits and shall promptly take all actions necessary to comply with all rules Laws, including, without limitation, the Occupational Safety and regulations. Landlord shall not knowingly discriminate against Tenant in LandlordHealth Act, regulating Tenant's enforcement specific use of the rules Premises or the Property. Tenant shall maintain in full force and regulationseffect all certifications or permissions to provide its services required by any authority having jurisdiction to authorize, franchise or regulate such services. Tenant shall be solely responsible for procuring and complying at all times with any and all necessary permits directly relating or incident to: the conduct of its specific activities on the Premises; its scientific experimentation, transportation, storage, handling, use and disposal of any chemical or radioactive or bacteriological substances or organisms or other hazardous wastes or environmentally dangerous substances or materials or medical waste, including without limitation the obtaining of an industrial discharge permit from the Massachusetts Water Resources Authority; its conduct of animal research activities; and its storage of fuel, chemicals, or other regulated materials permitted hereunder. Within 10 Business Days of a request by Landlord, Tenant shall furnish Landlord with copies of all such permits, together with a certificate certifying that such permits are all of the permits which Tenant is required to maintain with respect to the Premises.

Compliance with Laws; Use. The Premises Borrower shall be used only and/or shall cause Operating Lessee to obtain and at all times maintain, or use commercially reasonable efforts to cause the Manager to obtain and at all times maintain, all permits, Licenses (including the Liquor License and any other applicable liquor licenses or beverage permits), exemptions, and approvals necessary to construct, occupy, operate and market the Property, and shall maintain compliance in all material respects with all Requirements of Law applicable to the Property and all other applicable statutes, laws, regulations and ordinances necessary for the Permitted Use transaction of its business. If Borrower or Operating Lessee has received notice of any material violations of the aforesaid Requirements of Laws, applicable statutes, laws, regulations and ordinances, Borrower or Operating Lessee, as applicable, shall cure such violation within thirty (30) days of such notice provided that if such violation in not reasonably capable of being cured within such thirty (30) day period, Borrower or Operating Lessee, as applicable, shall have an additional ninety (90) days (for no other use whatsoevera total of 120 days) to cure such violation so long as Borrower or Operating Lessee, as applicable, commences the cure of such violation within such thirty (30) day period and diligently prosecutes, as determined by Administrative Agent, the cure of such violation. Tenant shall not use or permit The Property is a separate legal parcel lawfully created in compliance in all material respects with all subdivision laws and ordinances, and is properly zoned for the stated use of the Premises for any purpose which is illegal, dangerous Property as disclosed to persons Administrative Agent at the time of execution hereof. Neither Borrower nor Operating Lessee shall initiate or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants acquiesce to a zoning change of the Building Property without prior notice to, and prior written consent (not to be unreasonably withheld, delayed or interferes with conditioned) from, Administrative Agent. Furthermore, neither Borrower nor Operating Lessee shall allow changes in the operation stated use of the Building. Tenant shall comply with all Laws, including Property from that disclosed to Administrative Agent at the Americans with Disabilities Act, regarding the operation of Tenant's business and the use, condition, configuration and occupancy of the Premises. Tenant, within 10 Business Days after receipt, shall provide Landlord with copies of any notices it receives regarding a violation or alleged violation of any Laws. Except to the extent properly included in Expenses, Landlord shall be responsible for the cost of correcting any violations of Title III of the Americans with Disabilities Act (ADA) with respect to the Common Areas of the Building. Notwithstanding the foregoing, Landlord shall have the right to contest any alleged violation in good faith, including, Effective Date without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by law. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply with the terms of any final order or judgment. Tenant shall comply with the rules and regulations of the Building attached as Exhibit B and such other reasonable rules and regulations adopted by Landlord from time to time. Tenant shall also cause its agents, contractors, subcontractors, employees, customersprior notice to, and subtenants to comply with all rules and regulations. Landlord shall not knowingly discriminate against Tenant in Landlord's enforcement of the rules and regulationsprior written consent from, Administrative Agent.

Compliance with Laws; Use. A. The Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants of the Building or interferes with the operation of the Building. Tenant shall comply with all Laws, including the Americans with Disabilities Act, regarding the operation of Tenant's business and the use, condition, configuration and occupancy of the Premises. Tenant, within 10 Business Days days after receipt, shall provide Landlord with copies of any notices it receives regarding a violation or alleged violation of any Laws. Except Landlord, at its sole cost and expense (except to the extent properly included in Expenses), Landlord shall be responsible for the cost of correcting any violations of Title III of the Americans with Disabilities Act (ADA) with respect to the Common Areas of the BuildingBuilding and the restroom facilities and elevator lobbies within the Premises, provided that Landlord's obligation with respect to the restroom facilities and elevator lobbies within the Premises shall be limited to violations that arise out of the Landlord Lobby Work (as described in EXHIBIT D) and/or the condition of such portion of the Premises prior to any improvements performed by Tenant in such portions of the Premises and the installation of any furniture, equipment and other personal property of Tenant within such portion of the Premises. Notwithstanding the foregoing, Landlord shall have the right to contest any alleged violation in good faith, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by law. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply with the terms of any final order or judgment. Tenant Notwithstanding the foregoing, Tenant, not Landlord, shall comply be responsible for the correction of any violations that arise out of or in connection with the rules and regulations any claims brought under any provision of the Building attached as Exhibit B and such Americans with Disabilities Act other reasonable rules and regulations adopted by Landlord from time to time. Tenant shall also cause than Title III, the specific nature of Tenant's business in the Premises (other than general office use), the acts or omissions of Tenant, its agents, employees or contractors, subcontractorsTenant's arrangement of any furniture, employeesequipment or other property in the Premises, customersany repairs, alterations, additions or improvements performed by or on behalf of Tenant (other than the Landlord Lobby Work) and subtenants to comply with all rules and regulations. Landlord shall not knowingly discriminate against Tenant in Landlord's enforcement any design or configuration of the rules and regulationsPremises specifically requested by Tenant after being informed that such design or configuration may not be in strict compliance with the ADA.

Compliance with Laws; Use. The Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants of the Building or interferes with the operation of the Building. Tenant shall comply with all Lawsstatutes, codes, ordinances, orders, rules and regulations of any municipal or governmental entity whether in effect now or later, including the Americans with Disabilities ActAct (“Law(s)”), regarding the operation of Tenant's business and ’s business, the use, condition, configuration and occupancy of the Premises and the Building systems located in or exclusively serving the Premises. In addition, Tenant shall, at its sole cost and expense, promptly comply with any Laws that relate to the “Base Building” (defined below), but only to the extent such obligations are triggered by Tenant’s use of the Premises, within 10 Business Days after receiptother than for general office use, or Alterations or improvements in the Premises performed or requested by Tenant. However, nothing herein shall provide require Tenant to comply with Laws or requirements of public authorities which require the installation of new or additional mechanical, electrical, plumbing or fire/life safety systems on a Building-wide basis without reference to the particular use of Tenant or any Alterations performed by or for Tenant (“Building-Wide Laws”). Landlord with copies of any notices it receives regarding a violation or alleged violation of any Laws. Except will, at Landlord’s expense (except to the extent properly included in Expenses), perform all acts required to comply with such Building-Wide Laws as the same affect the Premises and the Building. In addition, Landlord shall be responsible responsible, at its cost (except to the extent properly included in Expenses), for the cost of correcting any violations of Title III of the Americans with Disabilities Act (ADA) with respect to the Common Areas of the BuildingBuilding except for any obligations specifically imposed upon Tenant pursuant to this Lease. Notwithstanding the foregoing, Landlord shall have the right to contest any alleged violation in good faith, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law Law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by lawLaw. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply with the terms of any final order or judgment. Tenant shall comply with the rules and regulations of the Building attached as Exhibit B and such other reasonable rules and regulations adopted by Landlord from time to time. Tenant shall also cause its agents, contractors, subcontractors, employees, customers, and subtenants to comply with all rules and regulations. Landlord shall not knowingly discriminate against Tenant in Landlord's enforcement of the rules and regulations.“

Compliance with Laws; Use. The Premises Borrower has, and at all times shall be used only have obtained, all permits, licenses, exemptions, and approvals necessary to construct, occupy, operate and market the Property, and shall maintain compliance with all Requirements of Law applicable to the Property and all other applicable statutes, laws, regulations and ordinances necessary for the Permitted Use transaction of its business. The Property is comprised of one or more legal parcels lawfully created in full compliance with all subdivision laws and ordinances, and is properly zoned for no other use whatsoever. Tenant shall not use or permit the stated use of the Premises for any purpose which is illegal, dangerous Property as disclosed to persons Administrative Agent at the time of execution hereof. Borrower shall not initiate or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants acquiesce to a zoning change of the Building or interferes Property without prior notice to, and prior written consent from, the Requisite Lenders, which consent shall not be unreasonably withheld by the Requisite Lenders so long as such changes (i) are consistent with the operation Xxxx Neighborhood Master Plan, (ii) do not result in a decrease in value or the economic feasibility of any of the Building. Tenant shall comply with all LawsProperty, including the Americans with Disabilities Act, regarding the operation of Tenant's business and the use, condition, configuration and occupancy (iii) add permitted uses but do not restrict any of the Premises. Tenant, within 10 Business Days after receipt, shall provide Landlord with copies of any notices it receives regarding a violation or alleged violation of any Laws. Except Property from continuing to the extent properly included in Expenses, Landlord shall be responsible used for the cost of correcting any violations of Title III its present use as of the Americans Effective Date. In connection with Disabilities Act (ADA) with respect to the Common Areas of the Building. Notwithstanding the foregoing, Landlord portions of the Property may be rezoned with the prior written consent of the Requisite Lenders to permit one or more hotels to be built on the Property, so long as (x) the Property may continue to be used for the same permitted uses for which such Property is being used as of the Effective Date and (y) the conditions in the preceding sentence are satisfied. Subject to the foregoing, Borrower shall have not allow changes in the right stated use of the Property from that disclosed to contest any alleged violation in good faithAdministrative Agent at the time of execution hereof without prior notice to, including, without limitationand prior written consent from, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by law. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply with the terms of any final order or judgment. Tenant shall comply with the rules and regulations of the Building attached as Exhibit B and such other reasonable rules and regulations adopted by Landlord from time to time. Tenant shall also cause its agents, contractors, subcontractors, employees, customers, and subtenants to comply with all rules and regulations. Landlord shall not knowingly discriminate against Tenant in Landlord's enforcement of the rules and regulationsRequisite Lenders.

Compliance with Laws; Use. The Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants of the Building or interferes with the operation of the Building. Tenant shall comply with all Laws, including the Americans with Disabilities Act, regarding the operation of Tenant's business and the use, condition, configuration and occupancy of the Premises. Tenant, within 10 Business Days days after receipt, shall provide Landlord with copies of any notices it receives regarding a violation or alleged violation of any Laws. Except Tenant shall comply with the rules and regulations of the Building attached as Exhibit B and such other reasonable rules and regulations adopted by Landlord from time to time. Tenant shall also cause its agents, contractors, subcontractors, employees, customers, and subtenants to comply with all rules and regulations. Landlord agrees not to enforce such rules and regulations in a manner that unreasonably discriminates against Tenant, recognizing that differing circumstances may justify different treatment. Notwithstanding the foregoing, Landlord, at its sole cost and expense (except to the extent properly included in Expenses), Landlord shall be responsible for the cost of correcting any violations of Title III of the Americans with Disabilities Act (ADA) with respect to the Premises and the Common Areas of the Building, provided that Landlord's obligation with respect to the Premises shall be limited to violations that arise out of the Landlord Work and/or the condition of the Premises prior to the installation of any furniture, equipment and other personal property of Tenant. Notwithstanding the foregoing, Landlord shall have the right to contest any alleged violation in good faith, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by law. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply with the terms of any final order or judgment. Tenant Notwithstanding the foregoing, Tenant, not Landlord, shall comply be responsible for the correction of any violations that arise out of or in connection with the rules and regulations any claims brought under any provision of the Building attached as Exhibit B and such Americans with Disabilities Act other reasonable rules and regulations adopted by Landlord from time to time. Tenant shall also cause than Title III which (i) arise out of the specific nature of Tenant's business in the Premises (other than general office use), (ii) arise out of the acts or omission of Tenant, its agents, employees and contractors, subcontractors(iii) arise out of Tenant's arrangement of any furniture, employeesequipment or other property in the Premises, customersor any repairs, alterations, additions or improvements performed by or on behalf of Tenant (other than the Landlord Work) and subtenants to comply with all rules and regulations. Landlord shall not knowingly discriminate against Tenant in Landlord's enforcement (iv) arise out of any design or configuration of the rules and regulationsPremises specifically requested by Tenant after being informed that such design or configuration may not be in strict compliance with the ADA.

Compliance with Laws; Use. The Premises shall will be used only for the Permitted Use and for no other use whatsoever. Tenant shall will not use or permit the use of the Premises for any purpose which is illegal, creates obnoxious odors (including but not limited to tobacco smoke), noises or vibrations, is dangerous to persons or property property, could increase Landlord's insurance costs, or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants of the Building or interferes with the operation of the Building. Except as provided below, the following uses are expressly prohibited in the Premises; government offices or agencies; personnel agencies; collection agencies; credit unions; telemarketing or reservation centers; medical treatment and health care; restaurants and other retail; customer service offices of a public utility company; or any other purpose which would, in Landlord's reasonable opinion, impair the reputation or quality of the Building, overburden any of the Building systems, Common Areas or parking, impair Landlord's efforts to lease space or otherwise interfere with the operation of the Property. Notwithstanding the foregoing, the following ancillary uses are permitted in the Premises only so long as they do not, in the aggregate, occupy more than 10% of the Rental Square Footage of the Premises or any single full floor (whichever is less): (A) the following services provided by Tenant exclusively to its employees: schools, training and other educational services; credit unions; and similar employee services; and (B) the following services directly and exclusively supporting Tenant's business; telemarketing; reservations; storage; debt collection; and similar support services. Subject to completion of Landlord's Construction Obligation, Tenant shall comply with all Laws, including the Americans ADA as well as any law, rule or regulation which must be complied with Disabilities Actto obtain a Certificate of Occupancy, regarding the operation of Tenant's business and the use, condition, configuration and occupancy of the Premises. Tenant, within 10 Business Days days after receipt, shall provide Landlord with copies of any notices it Tenant receives regarding a violation or of alleged violation of any Laws. Except to the extent properly included in Expenses, Landlord shall be responsible for the cost of correcting any violations of Title III of the Americans with Disabilities Act (ADA) with respect to the Common Areas of the Building. Notwithstanding the foregoing, Landlord shall have the right to contest any alleged violation in good faith, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by law. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply with the terms of any final order or judgment. Tenant shall comply with the rules and regulations of the Building attached as Exhibit B and such other reasonable rules and regulations (or modifications thereto) adopted by Landlord from time to time. Tenant shall also cause its agents, contractors, subcontractors, employees, customers, and subtenants to comply with all rules and regulations. Landlord Whenever a conflict shall not knowingly discriminate against Tenant in Landlord's enforcement arise between the language of this Lease and the rules and regulations, the terms of this Lease shall prevail.

Compliance with Laws; Use. 5.1 The Premises shall be used only for the Permitted Use and for no purposes reasonably incidental thereto consistent with a first class office project, and Tenant shall not use the Premises, or permit the Premises to be used, for any other use whatsoever. Subject to Landlord’s prior written approval of plans therefore, Tenant shall not have the right to use a portion of the Premises for the operation of, and include in the Tenant Improvements (or permit subsequent Alterations) the construction of, a kitchen/pantry facility (which in no event may include gas stoves or other gas appliances) for Tenant’s employees and guests only (in no event shall such kitchen/pantry facility be open to or serve the general public), including the installation of one or more dishwashers on and subject to the following terms and conditions: (i) Tenant shall be responsible, at its sole cost and expense (subject to the application of the Tenant Improvement Allowance), for obtaining all applicable permits, licenses and governmental approvals necessary for the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants of the Building or interferes with the operation of the Building. Tenant shall comply with all Laws, including the Americans with Disabilities Act, regarding the operation of Tenant's business and the use, condition, configuration and occupancy of the Premises. Tenant, within 10 Business Days after receipt, shall provide Landlord with copies of any notices it receives regarding a violation or alleged violation of any Laws. Except to the extent properly included in Expenses, Landlord shall be responsible for the cost of correcting any violations of Title III of the Americans with Disabilities Act such kitchen/pantry facility uses (ADA) with respect to the Common Areas of the Building. Notwithstanding the foregoing, Landlord shall have the right to contest any alleged violation in good faith, including, without limitation, any necessary approvals from the applicable health and/or fire departments, permits required in connection with any venting or other air-removal/circulation system, and any required fire-suppression systems), copies of which shall be delivered to Landlord prior to Tenant’s installation of any alterations in the Premises in connection with such kitchen/pantry facility uses; and (ii) in no event may such kitchen/cooking facility require any alterations to the Base Building. Tenant will additionally have the right to apply for and obtain devote a waiver or deferment of compliance, the right to assert any and all defenses allowed by law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by law. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply with the terms of any final order or judgment. Tenant shall comply with the rules and regulations reasonable portion of the Building attached as Exhibit B and Premises towards the operation of a fitness/wellness center for Tenant’s employees (including, at Tenant’s option, shower and/or locker facilities) subject to such other reasonable rules and regulations adopted by regarding such operations as Landlord from time to timemay implement for such fitness center. Tenant shall also cause its agentsThe uses prohibited under this Lease include, contractorswithout limitation, subcontractors, employees, customers, and subtenants to comply with all rules and regulations. Landlord shall not knowingly discriminate against Tenant in Landlord's enforcement use of the rules and regulations.Premises or a portion thereof for (i) offices of any agency or bureau of United States or any state or political subdivision thereof; (ii) offices or agencies of any foreign governmental or political subdivision thereof; (iii) offices of any

Compliance with Laws; Use. The Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's ’s reasonable opinion, unreasonably disturbs any other tenants of the Building or interferes with the operation of the Building. Tenant shall comply with all Laws, including the Americans with Disabilities Act, regarding the operation of Tenant's ’s business and the use, condition, configuration and occupancy of the Premises. Tenant, within 10 Business Days after receipt, shall provide Landlord with copies of any notices it receives regarding a violation or alleged violation of any Laws. Except to the extent properly included in Expenses, Landlord shall be responsible for the cost of correcting any violations of Title III of the Americans with Disabilities Act (ADA) with respect to the Common Areas of the Building. Notwithstanding the foregoing, Landlord shall have the right to contest any alleged violation in good faith, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law Law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by lawLaw. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply with the terms of any final order or judgment. Landlord shall comply with all Laws regarding the management and condition of the Common Areas. Tenant, within 10 days after receipt, shall provide Landlord with copies of any notices it receives regarding a violation or alleged violation of any Laws. Tenant shall comply with the rules and regulations of the Building attached as Exhibit B and such other reasonable rules and regulations adopted by Landlord from time to time. Tenant shall also cause its agents, contractors, subcontractors, employees, customers, and subtenants to comply with all rules and regulations. Landlord shall not knowingly discriminate against Tenant in Landlord's ’s enforcement of the rules and regulations. The rules and regulations shall be generally applicable, and generally applied in the same manner, to all tenants of the Building. If the Landlord reasonably determines that changes to the rules and regulations are required, Landlord agrees to provide Tenant with written notice of those changes. Notwithstanding the foregoing, in the event there is a conflict between this Lease and any rules and regulations enacted after the date of this Lease, the terms of this Lease shall control and no future rule or regulation shall unreasonably diminish Tenant’s rights hereunder.

Compliance with Laws; Use. The Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's ’s reasonable opinion, unreasonably disturbs any other tenants of the Building or interferes with the operation of the Building. Tenant shall comply with all Laws, including the Americans with Disabilities ActAct (except for Title III), regarding the operation of Tenant's ’s business in the Premises and the use, condition, configuration and occupancy of the Premises. Tenant; provided, within 10 Business Days after receipthowever, Tenant shall provide Landlord with copies in no event be obligated to perform or bear the cost of any notices it receives regarding work or repair of a violation capital or alleged violation structural nature in connection with compliance with any Laws applicable to the Premises unless required solely due to Tenant’s specific use of the Premises, or any Lawsmodifications, alterations or improvements by or for the benefit of Tenant. Except as expressly required by Tenant in the previous sentence, Landlord, at its sole cost and expense (except to the extent properly included in Expenses), Landlord shall be responsible for the cost of correcting any violations of compliance with all applicable Laws, including Title III of the Americans with Disabilities Act (ADA) with respect to the Premises and the Common Areas of the Building, provided that Landlord’s obligation with respect to the Premises shall be limited to violations of applicable Laws that arise out of base Building conditions in the Premises and not any alterations by Tenant prior to or after the Commencement Date, including, without limitation the Initial Alterations or the installation of any furniture, equipment and other personal property of Tenant. Notwithstanding the foregoing, so long as Tenant’s use and enjoyment of the Premises for the Permitted Use is not materially and adversely affected, Landlord shall have the right to contest any alleged violation in good faith, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law Law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by lawLaw. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply with the terms of any final order or judgment. Notwithstanding the foregoing, Tenant, not Landlord, shall be responsible for the correction of any violations in the Premises that result from or arise out of any claims brought under any applicable building code (that are not required to be paid by Landlord) or applicable provision of the Americans with Disabilities Act other than Title III, the specific nature of Tenant’s business in the Premises (other than general office use), the acts or omissions of Tenant, its agents, employees or contractors, Tenant’s arrangement of any furniture, equipment or other property in the Premises, and any repairs, alterations, additions or improvements performed by or on behalf of Tenant, any improvements or alterations by or on behalf of Tenant, including, without limitation the Initial Alterations and any design or configuration of the Premises constructed or installed by or at the request of Tenant after being informed, in writing, by an architect or other design professional that such design or configuration is not in strict compliance with the ADA. Tenant, within 10 days after receipt, shall provide Landlord with copies of any notices it receives regarding a violation or alleged violation of any Laws. Tenant shall comply with the rules and regulations of the Building attached as Exhibit B and such other reasonable rules and regulations adopted by Landlord from time to time. Tenant shall also use commercially reasonable efforts to cause its agents, contractors, subcontractors, employees, customers, clients and subtenants to comply with all rules and regulations; provided that Tenant shall only be responsible for the acts of its customers and clients to the extent that Tenant can reasonably control the actions of such parties. Landlord shall not knowingly discriminate against Tenant in Landlord's ’s enforcement of the rules and regulations. The rules and regulations will be generally applicable and generally applied in the same manner to all tenants in the Building. If there is a conflict between this Lease and any rules and regulations enacted after the date of this Lease, the terms of this Lease shall control.

Compliance with Laws; Use. The Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants of the Building or the Project or interferes with the operation of the BuildingBuilding or the Project. Subject to the express terms and conditions of this Lease, Tenant shall comply with all Laws, including the Americans with Disabilities Act, regarding the operation of Tenant's business and the use, condition, configuration and occupancy of the Premises. Tenant, within 10 Business Days days after receipt, shall provide Landlord with copies of any notices it receives regarding a violation or alleged violation of any Laws. Except to the extent properly included in Expenses, Landlord shall be responsible for the cost of correcting any violations of Title III of the Americans with Disabilities Act (ADA) with respect to the Common Areas of the Building. Notwithstanding the foregoing, Landlord shall have the right to contest any alleged violation in good faith, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by law. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply with the terms of any final order or judgment. Tenant shall comply with the rules and regulations of the Building attached as Exhibit B and such other reasonable rules and regulations adopted by Landlord from time to time. ; provided, however that such other reasonable rules and regulations shall not unreasonably and adversely (i) interfere with Tenant's use of the Premises, or (ii) diminish Tenant's parking rights as provided in the Parking Agreement attached hereto as Exhibit F. Tenant shall also cause its agents, contractors, subcontractors, employees, customers, and subtenants to comply with all rules and regulations. Landlord shall not knowingly discriminate against Tenant in Landlord's enforcement of the rules and regulations. Except to the extent caused by Tenant's or any of its employees', invitees', contractors' and/or agents' negligence or willful misconduct, Tenant shall not be liable for any of the costs and expenses, if any, associated with Landlord's or any other party's compliance with the City Parking Agreement. To the extent the railing located on the balcony of the second floor of the 2061 Building violates applicable Laws and the City of Mountain View has affirmatively and specifically required compliance therewith (collectively, the "Compliance Requirement"), Landlord shall, at its sole cost and expense, perform the work necessary to make the railing comply with Laws within 60 days following the date Landlord receives actual knowledge of the Compliance Requirement. The cost and expense to perform any such work shall not be allocated toward the ADA Costs Cap. Notwithstanding the foregoing, to the extent the same does not delay Tenant's construction schedule with respect to the Initial Alterations, Landlord shall have the right to contest the Compliance Requirement in good faith, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by Laws and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by Laws.

Compliance with Laws; Use. The Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants of the Building or interferes with the operation of the Buildingproperty. Tenant shall comply with all Laws, including the Americans with Disabilities Act, regarding the operation of Tenant's ’s business and the use, condition, configuration and occupancy of the Premises. Tenant, within 10 Business Days 30 days after receipt, shall provide Landlord with copies of any notices it receives regarding a violation or alleged violation of any Laws. Except Tenant shall not cause or permit the storage, release or disposal of any hazardous substances, wastes or materials, or any medical, special or infectious wastes (other than storage, use and disposal in the ordinary course of business in accordance with all applicable laws), on or about the Premises or the Buildings of which they are a part and Tenant shall be solely responsible for and shall promptly pay the cost of removing from the Premises all such hazardous substances, wastes and materials and any such medical, special and infectious waste placed on the Premises by Tenant, which removal shall be in accordance with all applicable Laws. Landlord shall be solely responsible for and shall promptly pay the cost of (i) removing from the Premises and remediation of all such hazardous substances, wastes and materials and any such medical, special and infectious waste that was present on the Premises prior to the Commencement Date to the extent properly included required by applicable Laws, which removal shall be at such time as may be required by applicable Laws and otherwise in Expensesaccordance with all applicable Laws, and (ii) restoring the Premises to substantially the same condition as existed immediately prior to such removal and remediation; provided, however, that Landlord shall not be required to remove, and Tenant shall be responsible for the cost disposal of, hazardous substances, wastes and materials that are currently or have been disposed of correcting any violations in the ordinary course of Title III business in the operation of the Americans a hospital facility, consistent with Disabilities Act (ADA) with respect to the Common Areas hospitals of the Buildingsimilar size, and Landlord’s past practice and applicable Laws. Notwithstanding the foregoingHazardous substances, Landlord wastes or materials shall have the right to contest any alleged violation include asbestos and those which are defined in good faithapplicable Laws, including, without limitationincluding but not limited to, the right Comprehensive Environmental Response, Compensation and Liability Act of 1980, as amended, 42 USC Section 9601 et seq; the Resource Conservation and Recovery Act, as amended, 42 USC Section 6901 et seq; the Toxic Substance Control Act, as amended 15 USC Section 2601. Medical, special or infectious wastes shall include those which are defined pursuant to apply for and obtain a waiver or deferment of compliance, applicable medical waste Laws. To the right to assert any and all defenses allowed by law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by law. , Landlord shall indemnify, defend and hold Tenant harmless from and against any claims or liability arising out of or connected with Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary ’s failure to comply with the terms of any final order Section V, which indemnification obligation shall survive the expiration or judgmentearlier termination of this Lease. Tenant shall comply with all applicable Laws which govern the rules use, storage handling and regulations disposal of the Building attached as Exhibit B hazardous substances, wastes or materials and such other reasonable rules and regulations adopted by Landlord from time to timemedical, special or infectious wastes. Tenant shall also cause its agentsindemnify, contractors, subcontractors, employees, customers, defend and subtenants hold Landlord harmless from and against any claims or liability arising out of or connected with Tenant’s failure to comply with all rules and regulationsthe terms of Section V, which 1 NTD: To be completed with current information prior to execution; if Closing occurs on June 30, this will be the most recent Index. Landlord indemnification obligation shall not knowingly discriminate against survive the expiration or earlier termination of this Lease. In no event shall such indemnification obligation of Tenant apply to any claims, loss, damage, events, acts or omissions occurring prior to the Commencement Date. Nothing herein will prohibit the use of hazardous substances in Landlord's enforcement non-significant quantities in the ordinary course of the rules and regulationsbusiness consistent with applicable Laws.

Compliance with Laws; Use. The Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's ’s reasonable opinion, unreasonably disturbs any other tenants of the Building or interferes with the operation of the Building. Tenant shall comply with all Laws, including the Americans with Disabilities Act, regarding the physical operation of Tenant's ’s business and the use, condition, configuration and occupancy of the Premises. Notwithstanding the foregoing, Tenant shall not be obligated to make any structural alterations or capital improvements to the Premises to comply with any Laws unless such compliance is required as the result of the specific nature of Tenant’s business in the Premises (other than general office use) or is the result of the acts or omissions of Tenant or its agents, employees or contractors or any design or configuration of the Premises specifically installed by Tenant excluding therefrom Tenant’s initial Leasehold Improvements (as defined in Article 8). Tenant, within 10 Business Days days after receipt, shall provide Landlord with copies of any notices it receives regarding a violation or alleged violation of any Laws. Except to the extent properly included in ExpensesTenant shall reimburse and compensate Landlord for all expenditures made by, or damages or fines sustained or incurred by, Landlord shall be responsible for the cost of correcting due to any violations of Title III of the Americans with Disabilities Act Laws by Tenant or any Tenant Related Parties (ADAas defined in Section 14.B hereof) with respect to the Common Areas of the Building. Notwithstanding the foregoing, Landlord shall have the right to contest any alleged violation in good faith, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by law. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply with the terms of any final order or judgmentPremises. Tenant shall comply with the rules and regulations of the Building attached as Exhibit B and such other reasonable rules and regulations adopted by Landlord from time to time. Tenant shall also cause its agents, contractors, subcontractors, employees, customers, employees and subtenants to comply with all rules and regulations. Landlord shall not knowingly discriminate against Tenant in Landlord's ’s enforcement of the rules and regulations. In the event of any inconsistency between such rules and regulations and the terms of this Lease, the terms of this Lease shall apply.

Compliance with Laws; Use. The Tenant shall use the Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants of the Building or interferes with the operation of the Buildingpurpose. Tenant shall comply with all Lawsstatutes, codes, ordinances, orders, rules and regulations of any municipal or governmental entity whether in effect now or later, including without limitation, the Environmental Health and Safety Laws (as defined in Exhibit F attached hereto) and the Americans with Disabilities ActAct (“Law(s)”), regarding the operation of Tenant's ’s business and the use, condition, configuration and occupancy of the Premises and the Building systems located in or exclusively serving the Premises. Tenant, within 10 Business Days after receipt, shall provide Landlord with copies Without limiting the generality of any notices it receives regarding a violation or alleged violation of any Laws. Except to the extent properly included in Expenses, Landlord shall be responsible for the cost of correcting any violations of Title III of the Americans with Disabilities Act (ADA) with respect to the Common Areas of the Building. Notwithstanding the foregoing, Landlord Tenant shall have the right be solely responsible for complying with all Laws that relate to contest any alleged violation in good faithoperations of Tenant’s laboratory and vivarium uses, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed Laws pertaining to equipment, installations and improvements used or required in connection with the operations of Tenant’s laboratory and vivarium uses. Tenant acknowledges and agrees that the vivarium shall be installed at Tenant’s sole cost and expense as further discussed in Exhibit F. The vivarium will be permitted to be operated only in the portion of the Premises shown on plans approved by law Landlord in accordance with Exhibit F attached hereto, and shall be used for biomedical research, development, handling and testing of the right Permitted Animals (as hereinafter defined) (“Animal Use”). Tenant shall not use any animals other than mice, rats, zebra fish and such other animals as are lawfully reasonably and customarily used in laboratories in Cambridge Massachusetts (the “Permitted Animals”) in its operations. In addition, Tenant shall promptly take any reasonable actions necessary to appeal resolve any decisionspicketing or public relations issues arising from Tenant’s Animal Use. Animal Use, judgments or rulings solely of the Permitted Animals, shall be permitted subject to the fullest extent following: (i) all research, development, handling and testing shall be conducted in strict compliance with all applicable Laws and with good scientific and medical practice; (ii) all dead animals, any part thereof or any waste products related thereto, shall be disposed of, at Tenant's sole cost and expense, in strict compliance with all applicable Laws and with good scientific and medical practice; (iii) no odors, noises or any similar nuisance shall be permitted by law. Landlord, after to emanate from or permeate outside the exhaustion vivarium; and (iv) Tenant's use of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply the vivarium shall not interfere with the terms peaceable and quiet use and enjoyment by other tenants or occupants of the Property. Xxxxxxxx’s permission in connection with any final order of the above shall not be unreasonably withheld, conditioned or judgmentdelayed. Upon written request, Tenant shall procure and deliver to Landlord copies of all necessary permits and approvals necessary for the use and operation of the vivarium before allowing any actual Permitted Animals onto the Premises and shall maintain such permits and approvals during the Term. Tenant shall comply with applicable laboratory practices, (including the rules use of safety equipment) and regulations policies established by the Center for Disease Control and Prevention (the “CDC”), and in no event shall Tenant’s use of the Building attached as Exhibit B Premises exceed BSL-2 requirements and such other reasonable rules and regulations adopted by Landlord protocols in effect with respect to Tenant’s use from time to time. In addition, Tenant shall also cause its agents, contractors, subcontractors, employees, customers, and subtenants to comply with all rules Good Manufacturing Practices (GMP) in order to conform to the guidelines recommended by agencies that control the authorization and regulations. Landlord shall not knowingly discriminate against Tenant in Landlord's enforcement licensing of the rules manufacture and regulations.sale of biologic, pharmaceutical, medical and other similar products. Tenant shall store, use and dispose of Hazardous Materials in compliance with all applicable Environmental, Health and Safety Laws and shall comply with all Laws applicable to the handling, use or

Compliance with Laws; Use. The Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants of the Building or interferes with the operation of the Building. Tenant shall comply with all Laws, including the Americans with Disabilities Act, regarding the operation of Tenant's business and the use, condition, configuration and occupancy of the Premises. Tenant, within 10 Business Days after receipt, shall provide Landlord with copies of any notices it receives regarding a violation or alleged violation of any Laws. Except to the extent properly included in Expenses, Landlord shall be responsible for the cost of correcting any violations of Title III of the Americans with Disabilities Act (ADA) and other Laws with respect to the Common Areas of the Building. Notwithstanding the foregoing, Landlord shall have the right to contest any alleged violation in good faith, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law Law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by lawLaw. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply with the terms of any final order or judgment. Tenant, within 10 days after receipt, shall provide Landlord with copies of any notices it receives regarding a violation or alleged violation of any Laws. Tenant shall comply with the rules and regulations of the Building attached as Exhibit B and such other reasonable rules and regulations adopted by Landlord from time to time. Tenant shall also cause its agents, contractors, subcontractors, employees, customers, and subtenants to comply with all rules and regulations. Landlord shall not knowingly discriminate against Tenant in Landlord's enforcement of the rules and regulations.

Compliance with Laws; Use. The Premises shall be used only for the Permitted Use and for no other use whatsoever. whatsoever Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants of the Building or interferes with the operation of the BuildingBuilding Landlord will make a good faith effort to impose substantially the same conditions as are set forth in this Article V on all other tenants in the Building which have not executed leases as of the date of Tenant's execution of this lease. Tenant shall comply with all Laws, including the Americans with Disabilities Act, regarding the operation of Tenant's business and the use, condition, configuration and occupancy of the Premises. Tenant, within 10 Business Days after receipt, shall provide Landlord with copies of any notices it receives regarding a violation or alleged violation of any Laws. Except to the extent properly included in Expenses, Landlord shall be responsible for the cost of correcting any violations of Title III of the Americans with Disabilities Act (ADA) with respect to the Common Areas of the Building. Notwithstanding the foregoing, Landlord shall have the right to contest any alleged violation in good faith, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law Law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by lawLaw. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply with the terms of any final order or judgment. Tenant within 10 days after receipt, shall provide Landlord with copies of any notices it receives regarding a violation or alleged violation of any Laws. Tenant shall comply with the rules and regulations of the Building attached as Exhibit B and such other reasonable rules and regulations adopted by Landlord from time to time. Tenant shall also cause its agents, contractors, subcontractors, employees, customers, and subtenants to comply with all rules and regulations. Landlord shall not knowingly discriminate against Tenant in Landlord's enforcement of the rules and regulations.

Compliance with Laws; Use. A. The Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants of the Building or the Project or interferes with the operation of the BuildingBuilding or the Project. Tenant shall comply with all Laws, including the Americans with Disabilities Act, regarding the operation of Tenant's business and the use, condition, configuration and occupancy of the Premises. Tenant, within 10 Business Days days after receipt, shall provide Landlord with copies of any notices it receives regarding a violation or alleged violation of any Laws. Except to the extent properly included in Expenses, Landlord shall be responsible for the cost of correcting any violations of Title III of the Americans with Disabilities Act (ADA) with respect to the Common Areas of the Building. Notwithstanding the foregoing, Landlord shall have the right to contest any alleged violation in good faith, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by law. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply with the terms of any final order or judgment. Tenant shall comply with the rules and regulations of the Building Project attached as Exhibit B and such other reasonable rules and regulations adopted by Landlord from time to time. Tenant shall also cause its agents, contractors, subcontractors, employees, customers, and subtenants to comply with all rules and regulations. Landlord shall not knowingly discriminate against Tenant in Landlord's enforcement of the rules and regulations. Except for Tenant's obligation to comply with the ADA as set forth above, nothing herein shall require Tenant to comply with Laws or requirements of public authorities which require the installation of new or additional structural, seismic, mechanical, electrical, plumbing or fire/life safety systems on a Project-wide basis without reference to the particular use of Tenant or any Alterations (including the Initial Alterations) performed by Tenant ("Project-Wide Laws"). Subject to Tenant's obligation to comply with the ADA as set forth above, Landlord will, at Landlord's expense (except to the extent properly included in Expenses), perform all acts required to comply with such Project-Wide Laws as the same affect the Premises, the Building and the Project. If there is a conflict between this Lease and any rules and regulations enacted after the date of this Lease, the terms of this Lease shall control.

Compliance with Laws; Use. The Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants occupants of the Building Property or unreasonably interferes with the operation of the BuildingPremises or the Property. Tenant shall comply with all Laws, including the Americans with Disabilities Act, regarding the operation of Tenant's business and the use, condition, configuration and occupancy of the Premises. Tenant, within 10 Business Days days after receipt, shall provide Landlord with copies of any notices it receives regarding a violation or alleged violation of any Laws. Except Laws relating to the extent properly included in Expensesuse, Landlord shall be responsible for the cost of correcting any violations of Title III condition, configuration or occupancy of the Americans with Disabilities Act (ADA) with respect to the Common Areas of the Building. Notwithstanding the foregoing, Landlord shall have the right to contest any alleged violation in good faith, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by law. Landlord, after the exhaustion of any and all rights to appeal or contest, will make all repairs, additions, alterations or improvements necessary to comply with the terms of any final order or judgmentPremises. Tenant shall comply with the rules and regulations of the Building Property attached as Exhibit B and such other reasonable rules and regulations adopted by Landlord from time to time. Tenant shall also cause its agents, contractors, subcontractors, employees, customers, and subtenants to comply with all rules and regulations. Landlord shall enforce the rules and regulations uniformly with respect to violations thereof of which it either has been notified or otherwise has actual knowledge, and shall not knowingly discriminate against Tenant in Landlord's enforcement of the rules and regulations. Tenant shall have access to the Premises 24 hours per day, 365 days per year. Landlord initially shall provide all Tenant employees assigned to the Premises, not exceeding fifty-five (55), with door keys and access cards at no additional costs to Tenant. If reasonably achievable within the design of Landlord's security system, Landlord will reasonably attempt to program its security system for the Building in a manner to allow Tenant's employees to utilize their access cards used at Tenant's headquarters (0000 Xxxxxxxx Xxxxxx East). If the Premises are subsequently expanded pursuant to the provisions of Section 6 below, or otherwise, Landlord shall provide Tenant with additional door keys and access cards at no additional cost to Tenant, and the number of such additional no-cost keys and cards issued with respect to the additional Rentable Area of the expanded Premises shall be in the same proportion as the fifty-five (55) cards issued initially bears to the initial Rentable Area of the Premises. Landlord may impose a reasonable charge, however, to replace keys and/or access cards which are lost or damaged, or to issue keys or access cards in addition to those which Landlord is required to initially provide to Tenant at no cost pursuant to this Section 5.

Compliance with Laws; Use. The Premises shall be used only for the Permitted Use and for no other use whatsoever. Tenant shall not use or permit the use of the Premises for any purpose which is illegal, dangerous to persons or property or which, in Landlord's reasonable opinion, unreasonably disturbs any other tenants of the Building or interferes with the operation of the Building. Tenant shall comply with all Lawsstatutes, codes, ordinances, orders, rules and regulations of any municipal or governmental entity whether in effect now or later, including the Americans with Disabilities ActAct (“Law(s)”), regarding the operation of Tenant's business and ’s business, the use, condition, configuration and occupancy of the Premises and the Building systems located in or exclusively serving the Premises. TenantDuring the Term, within 10 Business Days after receiptLandlord shall be responsible, shall provide Landlord with copies of any notices it receives regarding a violation or alleged violation of any Laws. Except at its cost (except to the extent properly included in Expenses), Landlord shall be responsible for the cost of correcting any violations of Title III Laws relating to or affecting the condition, use or occupancy of the Americans with Disabilities Act (ADA) with respect to the Common Areas of the Buildingexcept for any obligations specifically imposed upon Tenant pursuant to this Lease. Notwithstanding the foregoing, Landlord shall have the right to contest any alleged violation of any of the foregoing in good faith, or bring suit against any third party causing such violation of Laws, including, without limitation, the right to apply for and obtain a waiver or deferment of compliance, the right to assert any and all defenses allowed by law and the right to appeal any decisions, judgments or rulings to the fullest extent permitted by lawLaw. Landlord, after the exhaustion of any and all rights to appeal appeal, contest or contestlitigate, will make all repairs, additions, alterations alterations, improvements or improvements adjustments necessary to comply with the terms of any final order or judgment. In addition, Tenant shall shall, at its sole cost and expense, promptly comply with any Laws that relate to the rules and regulations “Base Building” (defined below), but only to the extent such obligations are triggered by Tenant’s use of the Building attached as Exhibit B and such Premises, other reasonable rules and regulations adopted than for general office use, or Alterations or improvements in the Premises performed or requested by Landlord from time to timeTenant. Tenant shall also cause its agents, contractors, subcontractors, employees, customers, and subtenants to comply with all rules and regulations. Landlord shall not knowingly discriminate against Tenant in Landlord's enforcement of the rules and regulations.“