Common use of CUSTOMER AGREEMENT FORM Clause in Contracts

CUSTOMER AGREEMENT FORM. INFORMED CONCENT FORM FOR ALL CUSTOMERS Informed consent is a process that provides education about genetics, and the options, benefits, limitations, and consequences of genetic testing. Genetic counseling enables an individual to provide informed consent prior to the decision to undergo testing. Given the complexity of the Test you have purchased from PerkinElmer Genomics, Inc., genetic counseling and informed consent by a trained medical geneticist or genetic counselor is strongly recommended prior to and after undergoing this testing and is available from the Ordering Provider. DNA TESTING OPTIONS WHOLE GENOME SEQUENCING (ADULT & PEDIATRIC) • Whole Genome Sequencing is a PerkinElmer Genomics test that involves sequencing the entire genome, which is all of the DNA in your cells. In other words, WGS sequences thousands of genes at the same time rather than sequencing only one or a few genes. • With WGS, large deletions or duplications of DNA segments in your genome can also be detected. • This test may detect variants in known disease-associated genes. In the latter case, we may not be able to know with certainty that the variant actually causes disease. • WGS requires either a saliva or dried blood spot sample. GENETIC INSIGHTS PANEL (PEDIATRIC) • The Genetic Insights Panel is a PerkinElmer Genomics test that involves the sequencing of over 270 genes associated with childhood-onset conditions. DNA will be extracted from the sample and sequencing of over 270 genes will be performed using Next Generation Sequencing (“NGS”) technology. • GIP requires a dried blood spot sample. HOW THE DNA TESTS ARE PERFORMED DNA will be extracted from your sample and sequencing of the genome will be performed using next generation sequencing (NGS) technology. A list of variants found in your sample will be generated. Variants believed to be disease-causing (pathogenic and likely pathogenic variants) will be presented in your results report. However, carrier status is not reported for Pediatric WGS or GIP. RESULTS DISCLOSURES MANDATORY DISCLOSURES FOR WGS (CHILDREN) • Diagnostic findings related to disease – pathogenic variant(s) and likely pathogenic variants(s) in genes interpreted to be responsible for or contributing to infantile and pediatric onset diseases will be reported to your Healthcare Professional(s).

CUSTOMER AGREEMENT FORM. INFORMED CONCENT FORM FOR ALL CUSTOMERS Informed consent is a process that provides education about genetics, and the options, benefits, limitations, and consequences of genetic testing. Genetic counseling enables an individual to provide informed consent prior to the decision to undergo testing. Given the complexity of the Test you have purchased from PerkinElmer GenomicsRevvity Omics, Inc., genetic counseling and informed consent by a trained medical geneticist or genetic counselor is strongly recommended prior to and after undergoing this testing and is available from the Ordering Provider. DNA TESTING OPTIONS WHOLE GENOME SEQUENCING (ADULT & PEDIATRIC) • Whole Genome Sequencing (WGS) is a PerkinElmer Genomics Revvity Omics test that involves sequencing the entire genome, which is all of the DNA in your cells. In other words, WGS sequences thousands of genes at the same time rather than sequencing only one or a few genes. • With WGS, large deletions or duplications of DNA segments in your genome can also be detected. • This test may detect variants in known disease-associated genes. In the latter case, we may not be able to know with certainty that the variant actually causes disease. • WGS requires either a saliva or dried blood spot sample. GENETIC INSIGHTS PANEL (PEDIATRIC) • The Genetic Insights Panel (GIP) is a PerkinElmer Genomics Revvity Omics test that involves the sequencing of over 270 genes specifically associated with childhood-onset conditions. DNA will be extracted from the sample and sequencing of over 270 genes will be performed using Next Generation Sequencing (“NGS”) technology. • GIP requires a dried blood spot sample. HOW THE DNA TESTS ARE PERFORMED DNA will be extracted from your sample and sequencing of the genome will be performed using next generation sequencing (NGS) technology. A list of variants found in your sample will be generated. Variants believed to be disease-causing (pathogenic and likely pathogenic variants) will be presented in your results report. HoweverFor Pediatric WGS or GIP, only actionable variants are reported and carrier status is not reported for Pediatric WGS or GIPreported. RESULTS DISCLOSURES MANDATORY DISCLOSURES FOR WGS (CHILDREN) • Diagnostic findings related to disease – pathogenic disease: Pathogenic variant(s) and likely pathogenic variants(s) in genes interpreted to be responsible for or contributing to infantile and pediatric onset diseases will be reported to your Healthcare Professional(s). Carrier status is not reported.