Dermal studies. The test substance shall be applied and kept on the skin for a minimum of 6 hours. The covering apparatus components shall be assayed to recover residual radioactivity. At the termination of the studies, each animal shall be sacrificed and the ex- posed skin area removed. An appro- priate section of the skin shall be solu- bilized and assayed for radioactivity to ascertain whether the skin acts as a reservoir for the test substance.
Appears in 10 contracts
Samples: Testing Consent Agreements and Test Rules, Testing Consent Agreements and Test Rules, Testing Consent Agreements and Test Rules
