Common use of Developing Event-Level Estimates Clause in Contracts

Developing Event-Level Estimates. The data in this file can be used to develop national 2015 event-level estimates for the U.S. civilian noninstitutionalized population on prescribed medicine purchases (events) as well as expenditures, and sources of payment for these purchases. Estimates of total number of purchases are the sum of the weight variable (PERWT15F) across relevant event records while estimates of other variables must be weighted by PERWT15F to be nationally representative. The tables below contain event-level estimates for selected variables. Selected Event (Purchase) Level Estimates All Prescribed Medicine Purchases Estimate of Interest Variable Name Estimate (SE) Number of purchases (in millions) PERWT15F 3410.5 (101.08) Mean total payments per purchase RXXP15X $109 (4.2) Mean out-of-pocket payment per purchase RXSF15X $14 (0.4) Mean proportion of expenditures paid by private insurance per purchase RXPV15X /RXXP15X 0.191 (0.0053) Example by Drug Type: Statins (TC1S1_1 = 173 or TC1S1_2 = 173 or TC1S2_1 = 173 or TC1S3_1 = 173 or TC2S1_1 = 173 or TC2S1_2 = 173) Estimate of Interest Variable Name Estimate (SE) Number of purchases (in millions) PERWT15F 232.3 (8.65) Mean total payments per purchase RXXP15X $75 (2.8) Mean annual total payments per person RXXP15X (aggregated across purchases within person) $406 (16.3)

Developing Event-Level Estimates. The data in this file can be used to develop national 2015 2014 event-level estimates for the U.S. civilian noninstitutionalized population on prescribed medicine purchases (events) as well as expenditures, and sources of payment for these purchases. Estimates of total number of purchases are the sum of the weight variable (PERWT15FPERWT14F) across relevant event records while estimates of other variables must be weighted by PERWT15F PERWT14F to be nationally representative. The tables below contain event-level estimates for selected variables. Selected Event (Purchase) Level Estimates All Prescribed Medicine Purchases Estimate of Interest Variable Name Estimate (SE) Number of purchases (in millions) PERWT15F 3410.5 PERWT14F 3421.2 (101.0897.80) Mean total payments per purchase RXXP15X RXXP14X $109 102 (4.24.5) Mean out-of-pocket payment per purchase RXSF15X RXSF14X $14 (0.4) Mean proportion of expenditures paid by private insurance per purchase RXPV15X /RXXP15X 0.191 RXPV14X /RXXP14X 0.158 (0.00530.0051) Example by Drug Type: Statins (TC1S1_1 = 173 or TC1S1_2 = 173 or TC1S2_1 = 173 or TC1S3_1 = 173 or TC2S1_1 = 173 or TC2S1_2 = 173) Estimate of Interest Variable Name Estimate (SE) Number of purchases (in millions) PERWT15F 232.3 PERWT14F 224.2 (8.657.63) Mean total payments per purchase RXXP15X RXXP14X $75 76 (2.82.9) Mean annual total payments per person RXXP15X RXXP14X (aggregated across purchases within person) $406 409 (16.3)

Developing Event-Level Estimates. The data in this file can be used to develop national 2015 2012 event-level estimates for the U.S. civilian noninstitutionalized population on prescribed medicine purchases (events) as well as expenditures, and sources of payment for these purchases. Estimates of total number of purchases are the sum of the weight variable (PERWT15FPERWT12F) across relevant event records while estimates of other variables must be weighted by PERWT15F PERWT12F to be nationally representative. The tables below contain event-level estimates for selected variables. Selected Event (Purchase) Level Estimates All Prescribed Medicine Purchases Estimate of Interest Variable Name Estimate (SE) Number of purchases (in millions) PERWT15F 3410.5 PERWT12F 3214.7 (101.0886.09) Mean total payments per purchase RXXP15X RXXP12X $109 91 (4.23.0) Mean out-of-pocket payment per purchase RXSF15X RXSF12X $14 17 (0.40.5) Estimate of Interest Variable Name Estimate (SE) Mean proportion of expenditures paid by private insurance per purchase RXPV15X /RXXP15X 0.191 RXPV12X /RXXP12X 0.167 (0.00530.0051) Example by Drug Type: Statins (TC1S1_1 = 173 or TC1S1_2 = 173 or TC1S2_1 = 173 or TC1S3_1 = 173 or TC2S1_1 = 173 or TC2S1_2 = 173) Estimate of Interest Variable Name Estimate (SE) Number of purchases (in millions) PERWT15F 232.3 PERWT12F 228.7 (8.657.53) Mean total payments per purchase RXXP15X RXXP12X $75 72 (2.82.4) Mean annual total payments per person RXXP15X RXXP12X (aggregated across purchases within person) $406 404 (16.313.6) Example by Associated Condition: Hypertension (RXICD1X = “401” or RXICD2X = “401” or RXICD3X = “401”) Estimate of Interest Variable Name Estimate (SE) Number of purchases (in millions) PERWT12F 494.4 (15.65) Mean total payments per purchase RXXP12X $39 (1.4) Mean annual total payments per person RXXP12X (aggregated across purchases within person) $332 (13.3)

Developing Event-Level Estimates. The data in this file can be used to develop national 2015 2010 event-level estimates for the U.S. civilian noninstitutionalized population on prescribed medicine purchases (events) as well as expenditures, and sources of payment for these purchases. Estimates of total number of purchases are the sum of the weight variable (PERWT15FPERWT10F) across relevant event records while estimates of other variables must be weighted by PERWT15F PERWT10F to be nationally representative. The tables below contain event-level estimates for selected variables. Selected Event (Purchase) Level Estimates All Prescribed Medicine Purchases Estimate of Interest Variable Name Estimate (SE) Number of purchases (in millions) PERWT15F 3410.5 PERWT10F 3273.4 (101.0883.93) Mean total payments per purchase RXXP15X RXXP10X $109 83 (4.21.7) Mean out-of-pocket payment per purchase RXSF15X RXSF10X $14 18 (0.4) Mean proportion of expenditures paid by private insurance per purchase RXPV15X /RXXP15X 0.191 RXPV10X /RXXP10X 0.171 (0.00530.0044) Example by Drug Type: Statins (TC1S1_1 = 173 or TC1S1_2 = 173 or TC1S2_1 = 173 or TC1S3_1 = 173 or TC2S1_1 = 173 or TC2S1_2 = 173) Estimate of Interest Variable Name Estimate (SE) Number of purchases (in millions) PERWT15F 232.3 PERWT10F 233.1 (8.656.99) Mean total payments per purchase RXXP15X RXXP10X $75 86 (2.82.7) Mean annual total payments per person RXXP15X RXXP10X (aggregated across purchases within person) $406 505 (16.316.2) Example by Associated Condition: Hypertension (RXICD1X = “401” or RXICD2X = “401” or RXICD3X = “401”) Estimate of Interest Variable Name Estimate (SE) Number of purchases (in millions) PERWT10F 514.4 (16.24) Mean total payments per purchase RXXP10X $40 (0.9) Mean annual total payments per person RXXP10X (aggregated across purchases within person) $367 (9.1)