Common use of Notices and Deliveries Clause in Contracts

Notices and Deliveries. Any notice, request, approval or consent required or permitted to be given under this Agreement shall be in writing and shall be deemed to have been sufficiently given if delivered in person, transmitted by facsimile (receipt verified) or by express courier service (signature required) to the Party to which it is directed at its address or facsimile number shown below or such other address or facsimile number as such Party shall have last given by notice to the other Party. If to Merck, addressed to: Merck XXxX Xxxxxxxxxxx Xxxxxxx 000 00000 Xxxxxxxxx Xxxxxxx Attn: Merck Serono Alliance Management Facsimile: +00 00 00 00 With a copy to: Merck XXxX Xxxxxxxxxxx Xxxxxxx 000 00000 Xxxxxxxxx Xxxxxxx Attn: Merck Serono Legal Department Facsimile: +00 00 00 00 00 00 If to Licensor, addressed to: Threshold Pharmaceuticals 000 Xxxxxx Xxx, Xxxxx 000 Xxxxx Xxx Xxxxxxxxx, XX 00000 XXX Attn: Vice President, Business Development Facsimile: (000) 000-0000 With a copy to: Xxxxxxxx & Xxxxxxxx LLP 000 Xxxx Xxxx Xxxx Xxxx Xxxx, XX 00000 XXX Attention: Xxxxxxx X. Xxxx Fax: (000) 000-0000

Notices and Deliveries. Any notice, request, approval approval, or consent required or permitted to be given under this Agreement shall be in writing and shall be deemed to have been sufficiently given if delivered in person, transmitted transmitted, by facsimile (receipt verified) ), or by express courier service (signature required) to the Party to which it is directed at its address or facsimile number shown below or such other address or facsimile number as such Party shall have last given by notice to the other Party. If to MerckDRI, addressed to: Merck XXxX Xxxxxxxxxxx Domain Russia Investments Limited c/o Xxxx Xxxxx LLP The Broadgate Tower, Third Floor 20 Primrose Street City of Xxxxxx, XX0X 0XX Xxxxxx Xxxxxxx 000 00000 Xxxxxxxxx Xxxxxxx AttnAttention: Merck Serono Alliance Management President & CEO Facsimile: +00 00 00 00 +00-00-0000-0000 With a copy to: Merck XXxX Xxxxxxxxxxx Xxxx Xxxxx, LLP 0000 Xxxxxx xx xxx Xxxxx, Xxxxx 000 Xxx Xxxxxxx, XX 00000 Fax: 000-000-0000 Attention: Xxxxxxx 000 00000 Xxxxxxxxx Xxxxxxx Attn: Merck Serono Legal Department Facsimile: +00 00 00 00 00 00 Xxxxxxx/Xxxxxx Xxxxx If to LicensorCompany, addressed to: Threshold Pharmaceuticals 000 Marinus Pharmaceuticals, Inc. 00 Xxxxxxxx Xxxx Xxxxx Xxxxxxxx, Xxxxxxxxxxx 00000 XXX Attention: President and CEO Facsimile: 203-3150565 With a copy to: Xxxxx Xxxxxx Xxx, LLP 00 Xxxxx 000 Xxxxx Xxx Xxxxxxxxx00xx Xxxxxx Xxxxxxxxxxxx, XX 00000 XXX Attn00000-0000 Attention: Vice President, Business Development Xxxxxxxx X. Xxxx Facsimile: (000) 000-0000 With a copy to: Xxxxxxxx & Xxxxxxxx LLP 000 Xxxx Xxxx Xxxx Xxxx Xxxx, XX 00000 XXX Attention: Xxxxxxx X. Xxxx Fax: (000) 000-0000

Notices and Deliveries. Any notice, request, approval approval, or consent required or permitted to be given under this Agreement shall be in writing and shall be deemed to have been sufficiently given if delivered in person, transmitted transmitted, by facsimile (receipt verified) ), or by express courier service (signature required) to the Party to which it is directed at its address or facsimile number shown below or such other address or facsimile number as such Party shall have last given by notice to the other Party. If to MerckDRI, addressed to: Merck XXxX Xxxxxxxxxxx Xxxxxxx Domain Russia Investments Limited c/x Xxxxxx Corporate Services Limited XX Xxx 000 00000 Xxxxxxxxx Xxxxxxx AttnXxxxxx Xxxxx Grand Cayman, KYI-1104, Cayman Islands Attention: Merck Serono Alliance Management President & CEO Facsimile: +00 00 00 00 With a copy to: Merck XXxX Xxxxxxxxxxx Xxxxxxx 000 00000 Xxxxxxxxx Xxxxxxx Attn: Merck Serono Legal Department Facsimile: +00 00 00 00 00 00 If to Licensor, addressed to: Threshold Pharmaceuticals 000 Xxxxxx Xxx, Xxxxx 000 Xxxxx Xxx Xxxxxxxxx, XX 00000 XXX Attn: Vice President, Business Development Facsimile: (000) 000+00-00-0000-0000 With a copy to: Xxxxxxxx & Xxxxxxxx Xxxx Xxxxx, LLP 0000 Xxxxxx xx xxx Xxxxx, Xxxxx 000 Xxxx Xxxx Xxxx Xxxx XxxxXxx Xxxxxxx, XX 00000 XXX Fax: 000-000-0000 Attn.: Xxxxxxx Xxxxxxx/Xxxxxx Xxxxx If to Company, addressed to: Regado Biosciences, Inc 000 Xxxxxxxxx Xxxxxx, Suite 130 Durham, North Carolina, 27701 USA Attention: President and CEO Facsimile: With a copy to: Xxxxxxxxxx Xxxxxxx, LLP 00 Xxxxxxxxxx Xxxxxx Roseland, New Jersey USA 07068 Attention: Xxxxxxx X. Xxxx FaxXxxxxx, Esq Facsimile: (000) 000-0000000-0000 If to NovaMedica, addressed to: NovaMedica LLC Attention: CEO, Xxxxxxxx Xxxxxx

Notices and Deliveries. Any notice, request, delivery, approval or consent required or permitted to be given under this Agreement shall be in writing and shall be deemed to have been sufficiently given if delivered in person, transmitted by facsimile (receipt verified) or by express courier service (signature required) or five (5) calendar days after it was sent by registered letter, return receipt requested (or its equivalent), to the Party to which it is directed at its address or facsimile number shown below or such other address or facsimile number as such Party shall have last given by notice to the other PartyParties. If to MerckLicensee, addressed to: Merck XXxX Xxxxxxxxxxx Xxxxx 0000, Xxx Xxxxxxxx Xxxxxx 0 Xxxxxxxxx Xxxxx, Xxxxxxx 000 00000 Xxxxxxxxx Xxxxxxx AttnXxxx Xxxx Attention: Merck Serono Alliance Management FacsimileOak Ma Fax: +00 00 00 00 [***] Email: [***] With a copy to: Merck XXxX Xxxxxxxxxxx Ropes & Xxxx XXX 00X Xxxx Xxxxx 0000 Xxxxxxx 000 00000 Xxxxxxxxx Xxxxxxx AttnXxxx Xxxx Xxxxxxxx, Xxxxx 000000 Attention: Merck Serono Legal Department FacsimileXxxxxx Xxx and Xxxxxxxx Xxx Fax: +00 00 00 00 00 00 [***] Email: [***]; and [***] If to LicensorCompany, addressed to: Threshold Pharmaceuticals Immunomedics, Inc. 000 Xxxxxx XxxXxx Xxxxxxxx Xxxx Xxxxxx, Plains NJ 07950 U.S.A. Attention: Xxxxx 000 Xxxxx Xxx Xxxxxxxxx, XX 00000 XXX AttnGeneral Counsel Email: Vice President, Business Development Facsimile: (000) 000-0000 [***] With a copy to: Xxxxxxxx & Xxxxxxxx DLA Piper LLP 000 Xxxx Xxxx Xxxx Xxxx Xxxx(US) One Liberty Place 0000 Xxxxxx Xxxxxx, Xxxxx 0000 Xxxxxxxxxxxx, XX 00000 XXX Attention: Xxxxxxx X. Xxxx Fax: (000) 000-0000Fahd M.T. Riaz, Esquire

Notices and Deliveries. Any notice, requestrequests, delivery, approval or consent required or permitted to be given under this Agreement shall be in writing and shall be deemed to have been sufficiently given if delivered in person, transmitted by commercial overnight courier, or transmitted by facsimile (receipt verified) or by express courier service (signature required) to the Party to which whom it is directed at its the address or facsimile number shown below or at such other address or facsimile number as such Party shall have last given by notice to the other Party. : If to Merck, addressed toXxxxx Xxxxx Sales AG Xxxxxxxxxxxxxxxxxxxxxx 00 XX-0000 Xxxxx Xxxxxxxxxxx Fax: Merck XXxX Xxxxxxxxxxx Xxxxxxx 000 00000 Xxxxxxxxx Xxxxxxx Attn+[####] Phone: Merck Serono Alliance Management Facsimile: +00 00 00 00 With +[####] with a copy to: Merck XXxX Lonza Biologies plc Head of Legal Services 000 Xxxx Xxxx Xxxxxx, Xxxxxxxxx, XXX 0XX, Xxxxxxx Fax:+ [####] Phone; +[####] If to : X. Xxxxxxxx-Xx Xxxxx Ltd Xxxxxxxxxxxxxxxxx 000 XX-0000 Xxxxx Xxxxxxxxxxx Xxxxxxx 000 00000 Xxxxxxxxx Xxxxxxx Attention: Legal Department Facsimile [####] Genentech, Inc. Attn: Merck Serono Legal Department Facsimile: +00 00 00 00 00 00 If to LicensorVice President, addressed to: Threshold Pharmaceuticals 000 Xxxxxx Xxx, Xxxxx 000 Genentech Partnering 0 XXX Xxx Xxxxx Xxx Xxxxxxxxx, XX 00000 XXX Attn: Vice President, Business Development Facsimile: (000) 000-0000 With a copy to: Xxxxxxxx & Xxxxxxxx LLP 000 Xxxx Xxxx Xxxx Xxxx Xxxx, XX 00000 XXX Attention: Xxxxxxx X. Xxxx X.X.X. Fax: (000) 000-0000. [####]

Notices and Deliveries. Any notice, request, approval or consent required or permitted to be given under this Agreement shall be in writing and shall be deemed to have been sufficiently given if and only if delivered in person, transmitted by facsimile (receipt verified) or by express or overnight courier service (signature required) to the Party to which it is directed at its physical address or facsimile number shown below or such other physical address or facsimile number as such Party shall have last given by such written notice to the other Party. If to MerckFBIO, addressed to: Merck XXxX Xxxxxxxxxxx Xxxxxxx 000 Fortress Biotech, Inc. 3 Colxxxxx Xxxxxx, 00xx Xxxxx Xxx Xxxx, XX 00000 Xxxxxxxxx Xxxxxxx AttnXxxention: Merck Serono Alliance Management FacsimileMichaxx X. Xxxxx, Xxxcutive Chairman Email: +00 00 00 00 msw@oxxxxxxxxxxxxxxxx.xxx With a copy to: Merck XXxX Xxxxxxxxxxx Xxxxxxx Foley & Xxrdner LLP 3000 X Xxxxxx, XX, Xxxxx 000 Xxxxxxxxxx, XX 00000 Xxxxxxxxx Xxxxxxx AttnXxxention: Merck Serono Legal Department Facsimile: +00 00 00 00 00 00 Gilbexxx X. Xxxxxxxxxx If to LicensorCephalon, addressed to: Threshold Pharmaceuticals 000 Xxxxxx XxxCephalon, Xxxxx 000 Xxxxx Xxx XxxxxxxxxInc. 41 Moxxxx Xxxx, Frazex, XX 00000 XXX Attn19355 Attention: Vice President, Business Development Facsimile: (000) 000-0000 Head of Alliance Management With a copy to: Xxxxxxxx & Xxxxxxxx LLP 000 Xxxx Xxxx Xxxx Xxxx Teva Pharmaceuticals 425 Pxxxxx Xxxx, Xxxxxxx, XX 00000 XXX AttentionXxxention: Xxxxxxx General Counsel and Goodwxx Xxxxter LLP 53 Stxxx Xxxxxx, Xxxxxx, XX 00000 Xxxention: Roberx X. Xxxx Fax: (000) 000-0000Xxxxxxxx

Notices and Deliveries. Any notice, request, approval or consent required or permitted to be given under this Agreement shall be in writing and shall be deemed to have been sufficiently given if delivered in person, transmitted by facsimile (receipt verified) or by express courier service (signature required) to the Party to which it is directed at its address or facsimile number shown below or such other address or facsimile number as such Party shall have last given by notice to the other Party. If to Merck, addressed to: Merck XXxX Xxxxxxxxxxx Xxxxxxx 000 00000 Xxxxxxxxx Xxxxxxx Attn: Merck Serono Alliance Management [*] Facsimile: +00 00 00 00 With +[*] In case of legal notices with a copy to: Merck XXxX Xxxxxxxxxxx Xxxxxxx 000 00000 Xxxxxxxxx Xxxxxxx Attn: Merck Serono Legal Department [*] Facsimile: +00 00 00 00 00 00 +[*] If to LicensorSutro, addressed to: Threshold Pharmaceuticals Sutro Bipharma Inc. 000 Xxxxxx Xxxx Xxx, Xxxxx 000 Xxxxx Xxx Xxxxxxxxx, XX 00000 XXX AttnTelephone : Vice President, Business Development Facsimile+[*] Telecopier : (000) 000-0000 With a copy to: Xxxxxxxx & Xxxxxxxx LLP 000 Xxxx Xxxx Xxxx Xxxx Xxxx, XX 00000 XXX Attention: Xxxxxxx X. Xxxx Fax: (000) 000-0000+[*]

Notices and Deliveries. Any notice, request, approval approval, or consent required or permitted to be given under this Agreement shall be in writing and shall be deemed to have been sufficiently given if delivered in person, transmitted by facsimile or email (receipt verified) or by express courier service (signature required) to the Party to which it is directed at its address or facsimile number or email shown below or such other address or facsimile number or email as such Party shall have last given by notice to the other Party. If to MerckMRKDG, addressed to: Merck XXxX Xxxxxxxxxxx Xxxxxxx Xxxxxx 000 00000 Xxxxxxxxx Xxxxxxx Attn: Merck Serono Alliance Management Facsimile: +00 00 00 00 With [*] with a copy copy, which shall not constitute notice, to: Merck XXxX Xxxxxxxxxxx Xxxxxxx Xxxxxx 000 00000 Xxxxxxxxx Xxxxxxx Attn: Merck Serono Legal Department Facsimile: +00 00 00 00 00 00 [*] If to LicensorCompany, addressed to: Threshold Pharmaceuticals Day One Biopharmaceuticals, Inc. 000 Xxxxxx XxxXxxxx Xxxxxxxxx, Xxxxx 000 Xxxxx Xxx Xxxxxxxxx, XX 00000 00000, XXX Attn: Vice President[*] with a copy, Business Development Facsimile: (000) 000-0000 With a copy which shall not constitute notice, to: Fenwick & West 000 Xxxxxxxxxx Xxxxxx Xxxxxxxx & Xxxxxxxx LLP 000 Xxxx Xxxx Xxxx Xxxx Xxxx, XX 00000 XXX Attention: Xxxxxxx X. Xxxx Fax: (000) 000-0000[*]

Notices and Deliveries. Any notice, requestrequests, delivery, approval or consent required or permitted to be given under this Agreement shall be in writing and shall be deemed to have been sufficiently given if delivered in person, transmitted by facsimile (receipt verified) commercial overnight courier, or transmitted by express courier service (signature required) telex telegram or telecopy to the Party to which whom it is directed at as its address or facsimile number shown below or such other address or facsimile number as such Party shall have last given by notice to the other Party. All notices shall be effective upon receipt. If to MerckIncyte, addressed to: Merck XXxX Xxxxxxxxxxx Xxxxxxx 000 00000 Xxxxxxxxx Xxxxxxx Incyte Pharmaceuticals, Inc. 3174 Xxxxxx Xxxxx Palo Alto, CA 94304 Attn: Merck Serono Alliance Management FacsimileRoy Xxxxxxxxx, XXO Tel: +00 00 00 00 With a copy to(415)-000-0000 Fax: Merck XXxX Xxxxxxxxxxx Xxxxxxx 000 00000 Xxxxxxxxx Xxxxxxx Attn: Merck Serono Legal Department Facsimile: +00 00 00 00 00 00 If (415)-000-0000 Xx to LicensorDiaDexus, addressed to: Threshold Pharmaceuticals 000 Xxxxxx XxxdiaDexus 3233 Xxxxx Xxxxxxxxx Suite 102 Santa Clara, Xxxxx 000 Xxxxx Xxx Xxxxxxxxx, XX 00000 XXX AttnCA 95054 Attention: Patrxxx Xxxxxxx Vice President, Business President Corporate Development FacsimileTel: (000) 000415)- Fax: (415)- If to SB, addressed to: SmithklineBeecham Corporation 709 Xxxxxxxxx Xxxx Xxxx xx Xxxxxxx, Xxxxxxxxxxxx 00000 Attention: Director, Alliance and Technology Group SmithKline Beecxxx Xxxrmaceuticals Tel: (610)-000-0000 With a Fax: (610)-000-0000 copy to: Xxxxxxxx & Xxxxxxxx LLP 000 SMITHKLINE BEECXXX XXXPORATION 709 Swedeland Road P.O. Xxx 0000 Xxxx Xxxx Xxxx Xxxx Xxxxxx Xxxxxxx, XX Xxxxxxxxxxxx 00000 XXX Attention: Xxxxxxx X. Xxxx Corporate Law Tel: (610)-000-0000 Fax: (000) 000610)-000-0000

Notices and Deliveries. Any noticenotices, request, delivery, approval or consent required or permitted to be given under this Agreement shall be in writing and shall be deemed to have been sufficiently given if when it is received, whether delivered in person, transmitted by facsimile with contemporaneous confirmation, by email, or delivery by registered letter (receipt verifiedor its equivalent) or delivery by express certified overnight courier service (signature required) service, to the Party to which it is directed at its address or facsimile number shown below or such other address or facsimile number as such Party shall have last given by notice to the other PartyParties. If to MerckLicensee: Provention Bio, addressed to: Merck XXxX Xxxxxxxxxxx Xxxxxxx Inc. 000 00000 Xxxxxxxxx Xxxxxxx Xxx Xxxxxxxx Xxxx Xxxxxxx, XX 0000 Attn: Merck Serono Alliance Management FacsimileXxxxxxxx Xxxxxx, President & CEO Email: +00 00 00 00 With xxxxxxx@xxxxxxxxx.xxx with a copy to: Merck XXxX Xxxxxxxxxxx Xxxxxxxxxx Xxxxxxx 000 00000 Xxxxxxxxx Xxxxxxx LLP 00 Xxxxxxxxxx Xxx. Roseland, NJ 07068 Attn: Merck Serono Legal Department FacsimileXxxxxxx X. Xxxxxx, Esq. Email: +00 00 00 00 00 00 xxxxxxx@xxxxxxxxxx.xxx If to Licensor: Xxxxxxx Research & Development, addressed to: Threshold Pharmaceuticals 000 Xxxxxx XxxLLC 0000 XxXxxx Xxxx Spring House, Xxxxx 000 Xxxxx Xxx Xxxxxxxxx, XX 00000 XXX PA 19477 Attn: Vice PresidentHead, Business Development FacsimileExternal Value Creation Email: (000) 000-0000 With xxxxxxx0@xxx.xxx.xxx with a copy to: Xxxxxxxx Chief Intellectual Property Counsel Xxxxxxx & Xxxxxxxx LLP 000 Xxxx Xxxx Xxxx Xxxx XxxxXxxxxxx 0 Xxxxxxx & Xxxxxxx Plaza New Brunswick, XX 00000 XXX AttentionNJ 08933 Email: Xxxxxxx X. Xxxx Fax: (000) 000-0000xxxxxxxxxxx@xxxxx.xxx.xxx

Notices and Deliveries. Any notice, request, approval or consent required or permitted to be given under this Agreement shall be in writing and shall be deemed to have been sufficiently given if delivered in person, transmitted by electronic mail, facsimile (receipt verified) or by express courier service (signature required) to the Party to which it is directed at its address or facsimile number shown below or such other address or facsimile number as such Party shall have last given by notice to the other Party. If to MerckCleave, addressed to: Merck XXxX Xxxxxxxxxxx Xxxxxxx ​ Cleave Therapeutics, Inc. 000 Xxxx Xxxxxx, Xxxxx 0000, Xxx Xxxxxxxxx, XX 00000 Xxxxxxxxx Xxxxxxx Attn: Merck Serono Alliance Management FacsimileCEO Email: +00 00 00 00 [***] ​ If to CASI, addressed to: ​ CASI Pharmaceuticals, Inc. 0000 Xxxxxxx Xxxxxx Xxxxx, Xxxxx 000 Xxxxxxxxx, XX 00000 Attn: Chief Operating Officer Email: [***] ​ With a copy to: Merck XXxX Xxxxxxxxxxx ​ Ropes & Xxxx LLP 00X, Xxxx Xxxxx 0000 Xxxxxxx 000 00000 Xxxxxxxxx Xxxxxxx Attn: Merck Serono Legal Department Facsimile: +00 00 00 00 00 00 If to Licensor, addressed to: Threshold Pharmaceuticals 000 Xxxxxx XxxXxxx Xxxx Xxxxxxxx, Xxxxx 000 Xxxxx Xxx Xxxxxxxxx, XX 00000 XXX Attn: Vice President, Business Development Facsimile: (000) 000-0000 With a copy to200040 Attention: Xxxxxxxx & Xxxxxxxx LLP 000 Xxxx Xxxx Xxxx Xxxx Xxxx, XX 00000 XXX Attention: Xxxxxxx Xxx and Xxxxx X. Xxxx Fax​ ​ ​ Email: (000) 000-0000[***]; [***] ​

Notices and Deliveries. Any notice, request, approval or consent required or permitted to be given under this Termination Agreement shall be in writing and shall be deemed to have been sufficiently given if delivered in person, transmitted by facsimile (receipt verified) or by express courier service (signature required) to the Party to which it is directed at its address or facsimile number shown below or such other address or facsimile number as such Party shall have last given by notice to the other Party. If to Merck, addressed to: Merck XXxX Xxxxxxxxxxx Xxxxxxx 000 00000 Xxxxxxxxx Xxxxxxx Attn: Merck Serono Head of Alliance Management Facsimile: +00 00 00 00 With a copy to: Merck XXxX Xxxxxxxxxxx Xxxxxxx 000 00000 Xxxxxxxxx Xxxxxxx Attn: Merck Serono Legal Department Facsimile: +00 00 00 00 00 00 If to LicensorThreshold, addressed to: Threshold Pharmaceuticals 000 Xxxxxx Xxx, Xxxxx 000 Xxxxx Xxx Xxxxxxxxx, XX 00000 XXX Attn: Vice President, Business Development Facsimile: (000) 000-0000 With a copy to: Xxxxxxxx & Xxxxxxxx LLP Threshold Pharmaceuticals 000 Xxxx Xxxx Xxxx Xxxx XxxxXxxxxx Xxx, Xxxxx 000 Xxxxx Xxx Xxxxxxxxx, XX 00000 XXX AttentionAttn: Xxxxxxx X. Xxxx FaxLegal Department Facsimile: (000) 000-0000

Notices and Deliveries. Any notice, request, approval or consent required or permitted to be given under this Agreement shall be in writing and shall be deemed to have been sufficiently given if and only if delivered in person, transmitted by facsimile (receipt verified) or by express or overnight courier service (signature required) to the Party to which it is directed at its physical address or facsimile number shown below or such other physical address or facsimile number as such Party shall have last given by such written notice to the other Party. If to MerckFBIO, addressed to: Merck XXxX Xxxxxxxxxxx Fortress Biotech, Inc. 0 Xxxxxxxx Xxxxxx, 00xx Xxxxx Xxx Xxxx, XX 00000 Attention: Xxxxxxx 000 00000 Xxxxxxxxx Xxxxxxx AttnX. Xxxxx, Executive Chairman Email: Merck Serono Alliance Management Facsimile: +00 00 00 00 xxx@xxxxxxxxxxxxxxxxx.xxx With a copy to: Merck XXxX Xxxxxxxxxxx Xxxxxxx Xxxxx & Lardner LLP 0000 X Xxxxxx, XX, Xxxxx 000 Xxxxxxxxxx, XX 00000 Xxxxxxxxx Xxxxxxx AttnAttention: Merck Serono Legal Department Facsimile: +00 00 00 00 00 00 Xxxxxxxx X. Xxxxxxxxxx If to LicensorCephalon, addressed to: Threshold Pharmaceuticals 000 Cephalon, Inc. 00 Xxxxxx XxxXxxx, Xxxxx 000 Xxxxx Xxx XxxxxxxxxXxxxxx, XX 00000 XXX AttnPA 19355 Attention: Vice President, Business Development Facsimile: (000) 000-0000 Head of Alliance Management With a copy to: Xxxxxxxx & Xxxxxxxx LLP Teva Pharmaceuticals 000 Xxxx Xxxx Xxxx Xxxx Xxxxxx Xxxx, Xxxxxxx, XX 00000 XXX Attention: General Counsel and Xxxxxxx Procter LLP 00 Xxxxx Xxxxxx, Xxxxxx, XX 00000 Attention: Xxxxxx X. Xxxx Fax: (000) 000-0000Xxxxxxxx

Notices and Deliveries. Any notice, request, approval or consent required or permitted to be given under this Agreement shall be in writing and shall be deemed to have been sufficiently given if delivered in person, transmitted by facsimile (receipt verified) or by express courier service (signature required) to the Party to which it is directed at its address or facsimile number shown below or such other address or facsimile number as such Party shall have last given by notice to the other Party. *** Confidential material redacted and filed separately with the Commission. If to Merck, addressed to: Merck XXxX Ares Trading SA Xxxx xxxxxxxxxxxx xx x’Xxxxxxxxx 0000 Xxxxxxx, Xxxxxxxxxxx Xxxxxxx 000 00000 Xxxxxxxxx Xxxxxxx Attn: Merck Serono Alliance Management General Manager Facsimile: +00 00 00 00 With a copy to: Merck XXxX Xxxxxxxxxxx Xxxxxxx 000 00000 Xxxxxxxxx Xxxxxxx Attn: Merck Serono Legal Department General Counsel Facsimile: +00 00 00 00 00 00 *** With a further copy to: Xxxxxx, Xxxxx & Xxxxxxx LLP 000 Xxxxxxxx Xxxxxx Xxxxxxxxx, Xxx Xxxxxx, XXX 00000 XXX Attn: Xxxxxxx X. Xxxxxxx If to Licensor, addressed to: Threshold Pharmaceuticals 000 Opexa Therapeutics, Inc. 0000 Xxxxxxxxxx Xxxxxx Xxx, Xxxxx 000 Xxxxx Xxxxxxxxx Xxx Xxxxxxxxx, XX 00000 XXX Attn: Vice President, Business Development Chief Executive Officer Facsimile: (000) 000-0000 With a copy to: Pillsbury Xxxxxxxx & Xxxxxxxx Xxxx Xxxxxxx, LLP 00000 Xx Xxxxxx Xxxx, Xxxxx 000 Xxxx Xxxx Xxxx Xxxx XxxxXxx Xxxxx, XX 00000 XXX AttentionAttn: Xxxxxxx X. Xxxx Fax: (000) 000-0000Xxxx

Notices and Deliveries. Any notice, request, approval or consent required or permitted to be given under this Agreement shall be in writing and shall be deemed to have been sufficiently given if delivered in person, transmitted by facsimile or email (receipt verified) or by express courier service (signature required) to the Party to which it is directed at its address, email address or facsimile number shown below or such other address, email address or facsimile number as such Party shall have last given by notice to the other Party. If to MerckATSA, addressed to: Merck XXxX Xxxxxxxxxxx Xxxxxxx Xxxxxx 000 00000 Xxxxxxxxx Xxxxxxx AttnAttention: Merck Serono Alliance Management Facsimile: +00 00 00 00 [***] Email Address: [***] With a copy copy, which shall not constitute notice, to: Merck XXxX Xxxxxxxxxxx Xxxxxxx Xxxxxx 000 00000 Xxxxxxxxx Xxxxxxx AttnAttention: Merck Serono Legal Department / LE-H Facsimile: +00 00 00 00 00 00 [***] Email Address: [***] If to LicensorCompany, addressed to: Threshold Pharmaceuticals Xxxx Therapeutics, Inc. 000 Xxxxxx Xxx, 0xx Xxxxx 000 Xxxxx Xxx Xxxxxxxxx, XX 00000 XXX AttnAttention: Vice President, Business Development FacsimileChief Executive Officer Email Address: (000) 000-0000 [***] With a copy copy, which shall not constitute notice, to: Xxxxxxxx & Xxxxxxxx Xxxxxx LLP 000 Xxxx Xxxx Xxxx 0000 Xxxxxxx Xxxxxx Xxxx Xxxx, XX 00000 00000, XXX AttentionAttn: Xxxxxxx X. Xxxx Fax[***] Email: (000) 000-0000[***]

Notices and Deliveries. Any notice, request, approval or consent required or permitted to be given under this Agreement shall be in writing and shall be deemed to have been sufficiently given if delivered in person, transmitted by facsimile (receipt verified) or by express courier service (signature required) to the Party to which it is directed at its address or facsimile number shown below or such other address or facsimile number as such Party shall have last given by notice to the other Party. If to Merck, addressed to: Merck XXxX Xxxxxxxxxxx Xxxxxxx 000 00000 Xxxxxxxxx Xxxxxxx Attn: Merck Serono Alliance Management [*] Facsimile: +00 00 00 00 With +[*] 51 *Confidential Treatment Requested. In case of legal notices with a copy to: Merck XXxX Xxxxxxxxxxx Xxxxxxx 000 00000 Xxxxxxxxx Xxxxxxx Attn: Merck Serono Legal Department [*] Facsimile: +00 00 00 00 00 00 +[*] If to LicensorSutro, addressed to: Threshold Pharmaceuticals Sutro Bipharma Inc. 000 Xxxxxx Xxxx Xxx, Xxxxx 000 Xxxxx Xxx Xxxxxxxxx, XX 00000 XXX AttnTelephone : Vice President, Business Development Facsimile+[*] Telecopier : (000) 000-0000 With a copy to: Xxxxxxxx & Xxxxxxxx LLP 000 Xxxx Xxxx Xxxx Xxxx Xxxx, XX 00000 XXX Attention: Xxxxxxx X. Xxxx Fax: (000) 000-0000+[*]

Notices and Deliveries. Any notice, request, approval or consent required or permitted to be given under this Agreement shall be in writing and shall be deemed to have been sufficiently given if and only if delivered in person, transmitted by facsimile (receipt verified) or by express or overnight courier service (signature required) to the Party to which it is directed at its physical address or facsimile number shown below or such other physical address or facsimile number as such Party shall have last given by such written notice to the other Party. If to MerckFBIO, addressed to: Merck XXxX Xxxxxxxxxxx Xxxxxxx 000 Fortress Biotech, Inc. 3 Xxxxxxxx Xxxxxx, 00xx Xxxxx Xxx Xxxx, XX 00000 Xxxxxxxxx Xxxxxxx AttnAttention: Merck Serono Alliance Management FacsimileMxxxxxx X. Xxxxx, Executive Chairman Email: +00 00 00 00 mxx@xxxxxxxxxxxxxxxxx.xxx With a copy to: Merck XXxX Xxxxxxxxxxx Xxxxxxx Fxxxx & Lardner LLP 3000 X Xxxxxx, XX, Xxxxx 000 Xxxxxxxxxx, XX 00000 Xxxxxxxxx Xxxxxxx AttnAttention: Merck Serono Legal Department Facsimile: +00 00 00 00 00 00 Gxxxxxxx X. Xxxxxxxxxx If to LicensorCephalon, addressed to: Threshold Pharmaceuticals 000 Cephalon, Inc. 40 Xxxxxx XxxXxxx, Xxxxx 000 Xxxxx Xxx XxxxxxxxxFrazer, XX 00000 XXX AttnPA 19355 Attention: Vice President, Business Development Facsimile: (000) 000-0000 Head of Alliance Management With a copy to: Xxxxxxxx & Xxxxxxxx LLP 000 Xxxx Xxxx Xxxx Xxxx Teva Pharmaceuticals 400 Xxxxxx Xxxx, Xxxxxxx, XX 00000 XXX Attention: Xxxxxxx General Counsel and Gxxxxxx Procter LLP 50 Xxxxx Xxxxxx, Xxxxxx, XX 00000 Attention: Rxxxxx X. Xxxx Fax: (000) 000-0000Xxxxxxxx

Notices and Deliveries. Any notice, request, approval or consent required or permitted to be given under this Agreement shall be in writing and shall be deemed to have been sufficiently given if delivered in person, transmitted by facsimile (receipt verified) or by express courier service (signature required) to the Party to which it is directed at its address or facsimile number shown below or such other address or facsimile number as such Party shall have last given by notice to the other Party. If to Merck, addressed to: Merck XXxX KGaA c/o Merck Serono International S.A. 0, Xxxxxx xxx Xxxxx 0000 Xxxxxx Xxxxxxxxxxx Xxxxxxx 000 00000 Xxxxxxxxx Xxxxxxx Attn: Merck Serono Alliance Management Facsimile: +00 00 00 00 *** ***CONFIDENTIAL PORTIONS OF THIS AGREEMENT HAVE BEEN OMITTED AND FILED SEPARATELY WITH THE COMMISSION PURSUANT TO A REQUEST FOR CONFIDENTIAL TREATMENT. With a copy to: Merck XXxX Xxxxxxxxxxx Xxxxxxx 000 00000 X-00000 Xxxxxxxxx Xxxxxxx Attn: Merck Serono Legal Department Facsimile: +00 00 00 00 00 00 *** If to LicensorLpath, addressed to: Threshold Pharmaceuticals 000 LPATH, Inc. 0000 Xxxxxx XxxXxxxxx, Xxxxx 000 Xxxxx Xxx XxxxxxxxxSuite A San Diego, XX 00000 XXX Attn: Vice President, Business Development Facsimile: (000) 000-0000 With a copy to: Xxxxxxxx & Xxxxxxxx LLP 000 Xxxx Xxxx Xxxx Xxxx Xxxx, XX 00000 XXX CA 92121 Attention: Xxxxxxx X. Xxxx Fax: (000) 000-0000President and CEO