Upfront Sample Clauses

Upfront. As a one-time, non-refundable consideration of the rights and licence granted by Ascendis to Licensee under this Agreement, Licensee shall issue and transfer to Ascendis [***] Series A-1 Preferred Shares in XXXXX Pharmaceuticals, corresponding to a total value of US[***] at the Effective Date.

Upfront. As partial payment for the rights and licenses granted to Sanofi by Ardelyx under this Agreement, Sanofi shall pay to Ardelyx a nonrefundable one-time upfront payment of one million two hundred fifty thousand U.S. dollars (U.S. $1,250,000) within ten (10) Business Days after the Effective Date against an invoice received by Sanofi from Ardelyx [***] Certain information in this document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions. no later than such date, which invoice may be sent on or after the Effective Date. The upfront payment shall not be creditable against any other payments Sanofi is obligated to make to Ardelyx under this Agreement.

Upfront. As partial payment for the rights and licenses granted to AstraZeneca by Ardelyx under this Agreement, AstraZeneca shall pay to Ardelyx a nonrefundable one-time upfront payment of thirty five million U.S. dollars (U.S. $35,000,000) within ten (10) Business Days after the Effective Date against an invoice received by AstraZeneca from Ardelyx fulfilling the requirements set forth in Section 9.12, which invoice may be sent on or after the Effective Date. The upfront payment shall not be creditable against any other payments AstraZeneca is obligated to make to Ardelyx under this Agreement. [***] Certain information in this document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions.

Upfront. Within 30 days after the signing of this Agreement, Prosensa shall pay to LUMC the following amounts: a. In partial consideration for the abandonment of the restrictions to the field, an amount of € 488.746,46 (four hundred eighty-eight thousand seven hundred and forty-six euros and forty-six cents) being the total out-of-pocket-expenses incurred by LUMC from September 1, 2003 until the Effective Amendment Date pursuant to Sections 7.4.1 and 7.4.3 of the Original Agreement as demonstrated by LUMC in the form of invoices from its external patent attorney(s); plus b. an amount of € 100,000 (one hundred thousand euro), being the milestone event set forth in Section 6.2(a) of the Original Agreement for the Initial Indication, which milestone event is deemed to be achieved; plus c. An upfront signing fee of € 100,000 (one hundred thousand euro).

Upfront. The Licensee shall pay Ascendis a one-time, non-refundable, upfront payment of Twenty Million US Dollars ($20,000,000) within [***] of the Effective Date. [***] Certain information in this document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions.

Upfront. No later than [***] after the Effective Date, Coya shall pay DRL a one-time, non-creditable and non-refundable license fee of [***].

Upfront. As payment for the rights and licenses granted to Fosun by Revance under this Agreement, Fosun shall pay to Revance a nonrefundable payment of thirty million U.S. dollars (USD $30 million) within thirty (30) Business Days after the Effective Date. The upfront payment shall not be creditable against any other payments Fosun is obligated to make to Revance under this Agreement.

Upfront. In consideration of the rights granted under this Agreement, the Licensee shall pay APR a fully earned, not creditable, not refundable, and not contingent upon any future performance or occurrence, upfront fee of USD $2,150,000 (two million one hundred fifty thousand US dollars) within 5 (five) Business Days from the signature of this Agreement by bank wire transfer in immediately available funds to a bank account designated by APR (the “Upfront”).

Upfront. Roche shall pay an upfront of one million US dollars (US$ 1,000,000), due [***] days from the Effective Date and receipt of an invoice from Synlogic.

Upfront. In partial consideration of the rights granted to Xxxxxxx under this Agreement, a non-refundable upfront payment in the amount of five million dollars (US) ($5,000,000) shall be due from Xxxxxxx to Xxxxx upon the Effective Date and payable within [*] ([*]) days thereof.