AMENDMENT NO. 1 TO PLEDGE AGREEMENT This Amendment No. 1 ("Amendment") to the Pledge Agreement dated February 24, 1997 made by Vicente Anido in favor of CombiChem, Inc. (the "Corporation"), as amended (the "Pledge Agreement"), is made as of this 8th...Pledge Agreement • March 31st, 1999 • Combichem Inc • Services-commercial physical & biological research • California
EXHIBIT 10.49 COMBICHEM, INC. STOCK OPTION AGREEMENT RECITALS A. The Board has adopted the Plan for the purpose of retaining the services of selected Employees, non-employee members of the Board or of the board of directors of any Parent or Subsidiary...Stock Option Agreement • May 4th, 1998 • Combichem Inc • Services-commercial physical & biological research • California
1 EXHIBIT 10.64 LIMITED LIABILITY COMPANY OPERATING AGREEMENTOperating Agreement • March 31st, 1999 • Combichem Inc • Services-commercial physical & biological research • California
2. 3 shall also mean (from and after the effectiveness of such amendment or the filing of such abbreviated registration statement) such registration statement as so amended, together with any such abbreviated registration statement. The term...Underwriting Agreement • December 3rd, 1997 • Combichem Inc • Services-commercial physical & biological research • California
LICENSE AGREEMENT BETWEEN COMBICHEM, INC. AND APERION LLC TABLE OF CONTENTSLicense Agreement • August 16th, 1999 • Combichem Inc • Services-commercial physical & biological research • California
1 EXHIBIT 10.71 SERVICES AGREEMENT THIS SERVICES AGREEMENT (this "Agreement") is made and entered into as of June 15, 1999 (the "Effective Date") by and among Catalytica Advanced Technologies, Inc., a Delaware corporation, of Mountain View, California...Services Agreement • August 16th, 1999 • Combichem Inc • Services-commercial physical & biological research
1 EXHIBIT 10.69 THE TRANSFER OF THIS WARRANT IS SUBJECT TO RESTRICTIONS CONTAINED HEREIN. THIS WARRANT HAS BEEN ISSUED IN RELIANCE UPON THE REPRESENTATION OF THE HOLDER THAT IT HAS BEEN ACQUIRED FOR INVESTMENT PURPOSES AND NOT WITH A VIEW TOWARD THE...Common Stock Purchase Warrant • May 17th, 1999 • Combichem Inc • Services-commercial physical & biological research • California
ADDENDUM TO STOCK OPTION AGREEMENTStock Option Agreement • December 3rd, 1997 • Combichem Inc • Services-commercial physical & biological research
1 EXHIBIT 10.38 LEASE AGREEMENT BY AND BETWEEN HARBOR INVESTMENT PARTNERS, A CALIFORNIA GENERAL PARTNERSHIPLease Agreement • October 15th, 1997 • Combichem Inc
2. 3 (d) Pledgor shall execute and deliver to Secured Party concurrently with the execution of this Agreement, and at any time and from time to time thereafter, all financing statements, assignments, continuation financing statements, termination...Pledge Agreement • October 15th, 1997 • Combichem Inc • California
3- 4 accumulated at the time the employment relationship terminates. All unused sick leave and other Fringe Benefits earned during the preceding twelve (12) month period ending on each anniversary of the date of this Agreement shall be forfeited if...Employment Agreement • October 15th, 1997 • Combichem Inc • California
LICENSE AGREEMENT BETWEEN COMBICHEM, INC. AND CHIROCHEM DISCOVERY SERVICES LLCLicense Agreement • March 31st, 1999 • Combichem Inc • Services-commercial physical & biological research • California
COMBICHEM, INC.Investors' Rights Agreement • October 15th, 1997 • Combichem Inc • California
1 Exhibit 10.18 MASTER LEASE AGREEMENT COMDISCO, INC. - LESSOR MASTER LEASE AGREEMENT DATED NOVEMBER 16, 1994, BY AND BETWEEN COMDISCO, INC. ("LESSOR") and COMBICHEM, INC. ("LESSEE"). IN CONSIDERATION OF THE MUTUAL AGREEMENTS DESCRIBED BELOW, THE...Master Lease Agreement • October 15th, 1997 • Combichem Inc • Illinois
2- 3 2. Stock Fully Paid; Reservation of Shares. All of the Shares issuable upon the exercise of the rights represented by this Warrant will, upon issuance and receipt of the Exercise Price therefor, be fully paid and nonassessable, and free from all...Stock Purchase Warrant • October 15th, 1997 • Combichem Inc • California
2 3 (a) Reclassification or Merger. In case of any reclassification, change or conversion of securities of the class issuable upon exercise of this Warrant (other than a change in par value, or from par value to no par value, or from no par value to...Warrant Agreement • October 15th, 1997 • Combichem Inc • California
1 EXHIBIT 10.2 PREFERRED STOCK PURCHASE AGREEMENT (200,000 Shares of Series Z Preferred Stock)Preferred Stock Purchase Agreement • October 15th, 1997 • Combichem Inc • California
COLLABORATION AGREEMENTCollaboration Agreement • December 11th, 1997 • Combichem Inc • Services-commercial physical & biological research • California
2 3 perform a material duty given to him by the company's Chief Executive Officer or under this agreement if such failure was continued for thirty (30) days after employee has been notified in writing by the company of his failure to perform; or (ix)...Employment Agreement • October 15th, 1997 • Combichem Inc • California
1 EXHIBIT 10.6 STOCK PURCHASE AGREEMENT THIS STOCK PURCHASE AGREEMENT ("Agreement") is made as of September 7, 1995 by and between CombiChem, Inc., a California corporation (the "Company") and Todd Schmidt, an individual resident of the State of...Stock Purchase Agreement • October 15th, 1997 • Combichem Inc • California
COMBICHEM, INC.Stock Issuance Agreement • May 4th, 1998 • Combichem Inc • Services-commercial physical & biological research • California
1 EXHIBIT 10.73 LIMITED LIABILITY COMPANY OPERATING AGREEMENTOperating Agreement • August 16th, 1999 • Combichem Inc • Services-commercial physical & biological research • Delaware
1 EXHIBIT 10.33 EMPLOYMENT AGREEMENT This EMPLOYMENT AGREEMENT (the "Agreement") is entered into as of March 14, 1996, by and between CombiChem, Inc., a California corporation ("Employer"), and Vicente Anido, Jr. ("Employee"). NOW, THEREFORE, the...Employment Agreement • October 15th, 1997 • Combichem Inc • California
1 EXHIBIT 10.41 COMBICHEM, INC. STOCK OPTION AGREEMENTStock Option Agreement • October 15th, 1997 • Combichem Inc • California
RECITALSCooperation Agreement • March 31st, 1999 • Combichem Inc • Services-commercial physical & biological research • California
1 EXHIBIT 10.32 EMPLOYMENT AGREEMENT This EMPLOYMENT AGREEMENT (the "Agreement") is entered into as of July 1, 1995, by and between CombiChem(TM), Inc., a California corporation ("Employer"), and Steven Teig ("Employee"). NOW, THEREFORE, the parties...Employment Agreement • October 15th, 1997 • Combichem Inc • California
EXHIBIT 10.3 STOCK PURCHASE AGREEMENT PREFERRED AND COMMON (400,000 Shares of Series A Preferred Stock and 100,000 Shares of Common Stock)Stock Purchase Agreement • October 15th, 1997 • Combichem Inc • California
RECITALS:Indemnification Agreement • October 15th, 1997 • Combichem Inc • Delaware
IMMEDIATELY EXERCISABLE REPURCHASE RIGHT RIGHT OF FIRST REFUSAL COMBICHEM, INC. STOCK PURCHASE AGREEMENT AGREEMENT made as of this ____ day of ________, 19__, by and among CombiChem, Inc. (the "Corporation"), ______________________, the holder of a...Stock Purchase Agreement • October 15th, 1997 • Combichem Inc • California
COMBICHEM, INC.Series D Preferred Stock Purchase Agreement • October 15th, 1997 • Combichem Inc • California
EXHIBIT 10.56 COMBICHEM, INC. AUTOMATIC STOCK OPTION AGREEMENT RECITALS A. The Corporation has implemented an automatic option grant program under the Plan pursuant to which eligible non-employee members of the Board will automatically receive special...Automatic Stock Option Agreement • May 4th, 1998 • Combichem Inc • Services-commercial physical & biological research • California
RESEARCH AND TECHNOLOGY DEVELOPMENT AGREEMENT BETWEEN COMBICHEM, INC. ANDResearch and Development • December 11th, 1997 • Combichem Inc • Services-commercial physical & biological research • California
1 EXHIBIT 10.70 COLLABORATIVE RESEARCH AND LICENSE AGREEMENTCollaborative Research and License Agreement • August 16th, 1999 • Combichem Inc • Services-commercial physical & biological research
RECITALS:Indemnification Agreement • October 15th, 1997 • Combichem Inc • Delaware
1 EXHIBIT 10.57 COMBICHEM, INC. STOCK PURCHASE AGREEMENT I hereby elect to participate in the 1997 Employee Stock Purchase Plan (the "ESPP") for the offering period specified below, and I hereby subscribe to purchase shares of Common Stock of...Stock Purchase Agreement • May 4th, 1998 • Combichem Inc • Services-commercial physical & biological research
