Minerva Neurosciences, Inc. Sample Contracts

5,000,000 Shares Minerva Neurosciences, Inc. UNDERWRITING AGREEMENT
Underwriting Agreement • June 29th, 2017 • Minerva Neurosciences, Inc. • Pharmaceutical preparations • New York
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MINERVA NEUROSCIENCES, INC. AND _____________, AS WARRANT AGENT FORM OF COMMON STOCK WARRANT AGREEMENT DATED AS OF __________
Warrant Agreement • September 14th, 2022 • Minerva Neurosciences, Inc. • Pharmaceutical preparations • New York

THIS COMMON STOCK WARRANT AGREEMENT (this “Agreement”), dated as of [•], between MINERVA NEUROSCIENCES, INC., a Delaware corporation (the “Company”), and [•], a [corporation] [national banking association] organized and existing under the laws of [•] and having a corporate trust office in [•], as warrant agent (the “Warrant Agent”).

MINERVA NEUROSCIENCES, INC. and , AS WARRANT AGENT FORM OF COMMON STOCK WARRANT AGREEMENT DATED AS OF [ ], 20
Common Stock Warrant Agreement • August 10th, 2018 • Minerva Neurosciences, Inc. • Pharmaceutical preparations • New York

COMMON STOCK WARRANT AGREEMENT (this “Agreement”), dated as of between MINERVA NEUROSCIENCES, INC., a Delaware corporation (the “Company”), and , a [corporation] [national banking association] organized and existing under the laws of and having a corporate trust office in , as warrant agent (the “Warrant Agent”).

MINERVA NEUROSCIENCES, INC. AND _____________, AS WARRANT AGENT FORM OF DEBT SECURITIES WARRANT AGREEMENT DATED AS OF __________
Warrant Agreement • September 14th, 2022 • Minerva Neurosciences, Inc. • Pharmaceutical preparations • New York

THIS DEBT SECURITIES WARRANT AGREEMENT (this “Agreement”), dated as of [•], between MINERVA NEUROSCIENCES, INC., a Delaware corporation (the “Company”), and [•], a [corporation] [national banking association] organized and existing under the laws of [•] and having a corporate trust office in [•], as warrant agent (the “Warrant Agent”).

OPEN MARKET SALE AGREEMENTSM
Minerva Neurosciences, Inc. • September 14th, 2022 • Pharmaceutical preparations • New York
MINERVA NEUROSCIENCES, INC. and , AS WARRANT AGENT FORM OF PREFERRED STOCK WARRANT AGREEMENT DATED AS OF [ ], 20
Preferred Stock Warrant Agreement • August 10th, 2018 • Minerva Neurosciences, Inc. • Pharmaceutical preparations • New York

PREFERRED STOCK WARRANT AGREEMENT (this “Agreement”), dated as of between MINERVA NEUROSCIENCES, INC., a Delaware corporation (the “Company”), and , a [corporation] [national banking association] organized and existing under the laws of and having a corporate trust office in , as warrant agent (the “Warrant Agent”).

LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • January 20th, 2015 • Minerva Neurosciences, Inc. • Pharmaceutical preparations

THIS LOAN AND SECURITY AGREEMENT (as the same may from time to time be amended, modified, supplemented or restated, this “Agreement”) dated as of January 16, 2015 (the “Effective Date”) among OXFORD FINANCE LLC, a Delaware limited liability company with an office located at 133 North Fairfax Street, Alexandria, Virginia 22314 (“Oxford”), as collateral agent (in such capacity, “Collateral Agent”), the Lenders listed on Schedule 1.1 hereof or otherwise a party hereto from time to time including Oxford in its capacity as a Lender and SILICON VALLEY BANK, a California corporation with an office located at 3003 Tasman Drive, Santa Clara, CA 95054 (“Bank” or “SVB”) (each a “Lender” and collectively, the “Lenders”), and MINERVA NEUROSCIENCES, INC., a Delaware corporation with offices located at 1601 Trapelo Road, Suite 284, Waltham, MA 02451 (“Borrower”), provides the terms on which the Lenders shall lend to Borrower and Borrower shall repay the Lenders. The parties agree as follows:

MINERVA NEUROSCIENCES, INC. and , AS WARRANT AGENT FORM OF DEBT SECURITIES WARRANT AGREEMENT DATED AS OF [ ], 20
Debt Securities Warrant Agreement • August 10th, 2018 • Minerva Neurosciences, Inc. • Pharmaceutical preparations • New York

DEBT SECURITIES WARRANT AGREEMENT (this “Agreement”), dated as of between MINERVA NEUROSCIENCES, INC., a Delaware corporation (the “Company”), and , a [corporation] [national banking association] organized and existing under the laws of and having a corporate trust office in , as warrant agent (the “Warrant Agent”).

FORM OF INDEMNIFICATION AGREEMENT
Form of Indemnification Agreement • June 10th, 2014 • Minerva Neurosciences, Inc. • Pharmaceutical preparations • Delaware

THIS INDEMNIFICATION AGREEMENT (the “Agreement”) is made and entered into as of , between Minerva Neurosciences, Inc., a Delaware corporation (the “Company”), and (“Indemnitee”).

REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • March 18th, 2015 • Minerva Neurosciences, Inc. • Pharmaceutical preparations • New York

REGISTRATION RIGHTS AGREEMENT (this “Agreement”), dated as of March 13, 2015, by and among Minerva Neurosciences, Inc., a Delaware corporation, with its principal offices at 1601 Trapelo Road, Suite 284, Waltham, MA 02451 (the “Company”), and the undersigned buyers (each, a “Buyer”, and collectively, the “Buyers”).

Contract
Minerva Neurosciences, Inc. • November 2nd, 2020 • Pharmaceutical preparations

Certain identified information identified with brackets (“[•••]”) has been excluded from this exhibit because it both (i) is not material and (ii) would be competitively harmful if publicly disclosed.

SECOND AMENDMENT TO LICENSE AGREEMENT
License Agreement • June 10th, 2014 • Minerva Neurosciences, Inc. • Pharmaceutical preparations • New York

This Second Amendment (“SECOND AMENDMENT”) dated as of 20 January, 2014 (“AMENDMENT DATE”) is entered into between Minerva Neurosciences, Inc. (F/K/A Cyrenaic Pharmaceuticals, Inc., a Delaware corporation, having a place of business located at 245 First Street, Suite 1800, Cambridge MA 02142, U.S.A. (“LICENSEE”) and Mitsubishi Tanabe Pharma Corporation, a Japanese corporation, having a place of business located at 6-18, Kitahama 2 Chome, Chuo-ku, Osaka 541-8505, Japan (“MTPC”).

June 12, 2018 Dear Devin,
Employment Agreement • May 6th, 2019 • Minerva Neurosciences, Inc. • Pharmaceutical preparations • Massachusetts

This agreement (hereafter "Employment Agreement") will formalize the terms and conditions of your employment with Minerva Neurosciences, Inc. (the "Company").

INVESTOR RIGHTS AGREEMENT
Investor Rights Agreement • June 10th, 2014 • Minerva Neurosciences, Inc. • Pharmaceutical preparations • Delaware

THIS INVESTOR RIGHTS AGREEMENT (this “Agreement”) is made on August 29, 2007 (the “Effective Date”) by and among Cyrenaic Pharmaceuticals, Inc., a Delaware corporation (the “Company”), and the Investors listed on Schedule I hereto (the “Investors”).

PROMISSORY NOTE
Promissory Note • June 10th, 2014 • Minerva Neurosciences, Inc. • Pharmaceutical preparations • Delaware

WHEREAS, Sonkei Pharmaceuticals, Inc., a Delaware corporation (the “Company”) has agreed to sell 1,112,500 shares of Company stock (“Restricted Stock”) to Maker, pursuant to that certain Subscription Agreement, dated as of the date hereof (the “Grant Agreement”);

EMPLOYMENT AGREEMENT between
Employment Agreement • April 9th, 2014 • Minerva Neurosciences, Inc. • Pharmaceutical preparations
PROMISSORY NOTE
Minerva Neurosciences, Inc. • June 10th, 2014 • Pharmaceutical preparations • Delaware

WHEREAS, Minerva Neurosciences, Inc., a Delaware corporation (the “Company”) has agreed to sell 97,737 shares of Company stock (“Restricted Stock”) to Maker, pursuant to that certain Subscription Agreement, dated as of the date hereof (the “Grant Agreement”);

October 4, 2013 Dr. Rogerio Vivaldi Coelho Brookline, MA, 02467 US Dear Rogerio:
Minerva Neurosciences, Inc. • June 10th, 2014 • Pharmaceutical preparations • Massachusetts

Further to our offer letter to you dated September 17, 2013 (the “Offer Letter”), this agreement (this “Employment Agreement”) will formalize the terms and conditions of your employment with Cyrenaic Pharmaceuticals, Inc. (the “Company”).

CO-DEVELOPMENT AND LICENSE AGREEMENT BY AND BETWEEN JANSSEN PHARMACEUTICA, N.V. AND MINERVA NEUROSCIENCES, INC. DATED FEBRUARY 13, 2014
Development and License Agreement • June 10th, 2014 • Minerva Neurosciences, Inc. • Pharmaceutical preparations • New York

THIS CO-DEVELOPMENT AND LICENSE AGREEMENT (the “Agreement”), executed as of February 13, 2014 (the “Execution Date”), is made by and between Janssen Pharmaceutica, N.V., a corporation organized and existing under the laws of Belgium, having its principal place of business is at Turnhoutseweg 30, 2340 Beerse, Belgium (hereinafter “Janssen”), and Minerva Neurosciences, Inc., a corporation organized under the laws of the State of Delaware, having its principal place of business at 245 First Street, Cambridge, Massachusetts (hereinafter “Minerva”). Janssen and Minerva are sometimes referred to herein individually as a “Party” and collectively as the “Parties.”

December 23, 2013 Joseph Reilly 12 Nelson Way Wilmington, MA 01887 Dear Joe:
Minerva Neurosciences, Inc. • June 10th, 2014 • Pharmaceutical preparations • Massachusetts

Further to our offer letter to you dated December 13, 2013 (the “Offer Letter”), this agreement (this “Employment Agreement”) will formalize the terms and conditions of your employment with Minerva Neurosciences, Inc. (the “Company”).

SHARE PURCHASE AGREEMENT dated as of February 11, 2014 among MINERVA NEUROSCIENCES, INC., MIND-NRG SA and THE PARTIES SET FORTH ON SCHEDULE A Relating to the Purchase and Sale of 100% of the capital stock of MIND-NRG SA
Share Purchase Agreement • April 9th, 2014 • Minerva Neurosciences, Inc. • Pharmaceutical preparations

This SHARE PURCHASE AGREEMENT, is made and entered into as of February 11, 2014 (the “Agreement”), by and among MINERVA NEUROSCIENCES, INC., a Delaware corporation (“Buyer”), Mind-NRG SA, a Swiss corporation (société anonyme/Aktiengesellschaft) (the “Company”), and the parties set forth on Schedule A hereto (the “Shareholders”).

LICENSE AGREEMENT
License Agreement • June 10th, 2014 • Minerva Neurosciences, Inc. • Pharmaceutical preparations • New York

THIS LICENSE AGREEMENT (hereinafter referred to as “Agreement”) dated as of 30 August, 2007 (hereinafter referred to as “Effective Date”), is entered into between Cyrenaic Pharmaceuticals, Inc., a Delaware corporation, having a place of business located at 47 Hulfish Street, Suite 310 Princeton NJ 08542, the U.S. (hereinafter referred to as “LICENSEE”) and Mitsubishi Pharma Corporation, a Japanese corporation, having a place of business located at 6-9, Hiranomachi 2-chome, Chuo-ku, Osaka 541-0046, Japan (hereinafter referred to as “MPC”).

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CONSULTING AGREEMENT
Consulting Agreement • April 9th, 2014 • Minerva Neurosciences, Inc. • Pharmaceutical preparations • New York

This CONSULTING AGREEMENT (this “Agreement”) is entered into as of 1st October, 2011, by and between Sonkei Pharmaceuticals Inc, a Delaware corporation (the “Company”), and Geoff Race, an individual (“Consultant”).

LICENSE AGREEMENT
License Agreement • June 10th, 2014 • Minerva Neurosciences, Inc. • Pharmaceutical preparations • New York

THIS LICENSE AGREEMENT (hereinafter referred to as “Agreement”) dated as of September 1, 2008 (hereinafter referred to as “Effective Date”), is entered into between Sonkei Pharmaceuticals, Inc., a Delaware corporation, having a place of business located at 47 Hulfish Street, Suite 310, Princeton, NJ 08542, United States of America (hereinafter referred to as “LICENSEE”) and Mitsubishi Tanabe Pharma Corporation, a Japanese corporation, having a place of business located at 2-10, Dosho-machi 3 chome, Chuo-ku, Osaka 541-8505, Japan (hereinafter referred to as “MTPC”).

AMENDMENT NO. 1 TO INVESTOR RIGHTS AGREEMENT
Investor Rights Agreement • June 10th, 2014 • Minerva Neurosciences, Inc. • Pharmaceutical preparations • Delaware

THIS AMENDMENT NO. 1 TO INVESTMENT RIGHTS AGREEMENT (this “Amendment”), dated as of December 20, 2013, is made by and among Minerva Neurosciences, Inc., a Delaware corporation, as the corporate successor to Cyrenaic Pharmaceuticals, Inc. (the “Company”), and the undersigned investors of the Company (the “Investors”).

AMENDMENT TO LICENSE AGREEMENT
License Agreement • June 10th, 2014 • Minerva Neurosciences, Inc. • Pharmaceutical preparations

This Amendment dated as of 16th June, 2011 is entered into between Cyrenaic Pharmaceuticals, Inc., a Delaware corporation, having a place of business located at 47 Hulfish Street, Suite 310 Princeton NJ 08542, U.S.A. (“LICENSEE”) and Mitsubishi Tanabe Pharma Corporation, a Japanese corporation, having a place of business located at 6-18, Kitahama 2 Chome, Chuo-ku, Osaka 541-8505, Japan (“MTPC”).

COMMON STOCK PURCHASE AGREEMENT
Common Stock Purchase Agreement • April 9th, 2014 • Minerva Neurosciences, Inc. • Pharmaceutical preparations • New Jersey

This COMMON STOCK PURCHASE AGREEMENT (“Agreement”) is made as of February 13, 2014 (the “Effective Date”), by and between Minerva Neurosciences, Inc., a Delaware corporation (the “Company”), and Johnson & Johnson Development Corporation, a New Jersey corporation (the “Investor”).

September 2, 2021 Jay B. Saoud Groton, MA 01450 Re: Transition, Separation, and Consulting Agreement Dear Jay:
Minerva Neurosciences, Inc. • September 8th, 2021 • Pharmaceutical preparations • Massachusetts

This letter sets forth the terms of the transition, separation, and consulting agreement (the “Agreement”) that Minerva Neurosciences, Inc. (the “Company”) is offering to you to aid in your transition.

SECOND AMENDMENT TO LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • February 25th, 2016 • Minerva Neurosciences, Inc. • Pharmaceutical preparations

THIS SECOND AMENDMENT TO LOAN AND SECURITY AGREEMENT (this “Amendment”) is entered into as of February 23, 2016, by and among OXFORD FINANCE LLC (“Oxford”) as collateral agent (in such capacity, “Collateral Agent”), the Lenders listed on Schedule 1.1 of the Loan Agreement (as defined below) or otherwise a party thereto from time to time, including without limitation, Oxford in its capacity as a Lender, and SILICON VALLEY BANK, a California corporation (“SVB”) (in such capacity, each a “Lender” and collectively, the “Lenders”), and MINERVA NEUROSCIENCES, INC., a Delaware corporation (“Borrower”).

May 30, 2014 Fred Ahlholm Dear Fred:
Employment Agreement • November 5th, 2015 • Minerva Neurosciences, Inc. • Pharmaceutical preparations • Massachusetts

This agreement (hereafter “Employment Agreement”) will formalize the terms and conditions of your employment with Minerva Neurosciences, Inc. (the “Company”).

Contract
Minerva Neurosciences, Inc. • May 12th, 2021 • Pharmaceutical preparations

Certain identified information identified with brackets (“[•••]”) has been excluded from this exhibit because it both (i) is not material and (ii) would be competitively harmful if publicly disclosed.

EMPLOYMENT AGREEMENT
Employment Agreement • August 4th, 2016 • Minerva Neurosciences, Inc. • Pharmaceutical preparations
SUBLEASE AGREEMENT
Sublease Agreement • October 6th, 2017 • Minerva Neurosciences, Inc. • Pharmaceutical preparations • Massachusetts

THIS SUBLEASE AGREEMENT (this “Sublease”), dated as of October 2, 2017, is entered into by and between Profitect, Inc., a Delaware corporation, (“Sublandlord”), and Minerva Neurosciences, Inc., a Delaware corporation, (“Subtenant”).

REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • April 9th, 2014 • Minerva Neurosciences, Inc. • Pharmaceutical preparations • New Jersey

This REGISTRATION RIGHTS AGREEMENT (the “Agreement”) is made and entered into as of February 13, 2014 (the “Effective Date”) by and between Minerva Neurosciences, Inc., a Delaware corporation (the “Company”) and Johnson & Johnson Development Corporation, a New Jersey corporation (the “Investor”).

SECOND AMENDMENT TO LICENSE AGREEMENT
License Agreement • May 7th, 2015 • Minerva Neurosciences, Inc. • Pharmaceutical preparations

This SECOND AMENDMENT TO LICENSE AGREEMENT (this “AMENDMENT”), dated as of April 21, 2015 (the “EFFECTIVE DATE”), is entered into by and between Minerva Neurosciences, Inc. (formerly known as Sonkei Pharmaceuticals, Inc.), a Delaware corporation with offices at 1601 Trapelo Road, Suite 284,Waltham, MA 02451 (“LICENSEE”), and Mitsubishi Tanabe Pharma Corporation, a Japanese corporation with offices at 3-2-10 Dosho-machi, Chuo-ku, Osaka 541-8505, Japan (“MTPC”).

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