ASLAN Pharmaceuticals LTD Sample Contracts

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OPEN MARKET SALE AGREEMENTSM
Open Market Sale Agreement • October 9th, 2020 • ASLAN Pharmaceuticals LTD • Pharmaceutical preparations • New York
SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • March 13th, 2024 • ASLAN Pharmaceuticals LTD • Pharmaceutical preparations • New York

This Securities Purchase Agreement (this “Agreement”), dated as of March 12, 2024, is between ASLAN Pharmaceuticals Limited, an exempted company with limited liability incorporated under the laws of the Cayman Islands (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively the “Purchasers”).

FORM OF WARRANT TO PURCHASE ORDINARY SHARES REPRESENTED BY AMERICAN DEPOSITARY SHARES ASLAN Pharmaceuticals Limited
Warrant Agreement • March 13th, 2024 • ASLAN Pharmaceuticals LTD • Pharmaceutical preparations

THIS WARRANT TO PURCHASE ORDINARY SHARES REPRESENTED BY AMERICAN DEPOSITARY SHARES (the “Warrant”), issued in the form of uncertificated securities, certifies that, for value received, ______ or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after the date hereof (the “Initial Exercise Date”) and on or prior to 5:00 p.m. (New York City time) on ______, 2029 (the “Termination Date”) but not thereafter, to subscribe for and purchase from ASLAN Pharmaceuticals Limited, an exempted company with limited liability incorporated under the laws of the Cayman Islands (the “Company”), up to ______ Ordinary Shares, nominal or par value $0.01 per share (as subject to adjustment hereunder) (the “Warrant Shares”), represented by _________ American Depositary Shares (“ADSs”), each twenty-five (25) Ordinary Shares represented by one (1) ADS (as subject to adjustment hereunder) (the “Warrant AD

INDEMNITY AGREEMENT
Indemnification Agreement • April 16th, 2018 • ASLAN Pharmaceuticals LTD • Pharmaceutical preparations • California

THIS INDEMNITY AGREEMENT (this “Agreement”) dated as of , 2018, is made by and between , an exempted company incorporated in the Cayman Islands (the “Company”), and (“Indemnitee”).

WARRANT TO PURCHASE ORDINARY SHARES REPRESENTED BY AMERICAN DEPOSITARY SHARES [OR PRE-FUNDED WARRANTS] ASLAN PHARMACEUTICALS LIMITED
Security Agreement • February 24th, 2023 • ASLAN Pharmaceuticals LTD • Pharmaceutical preparations

THIS WARRANT TO PURCHASE (A) ORDINARY SHARES REPRESENTED BY AMERICAN DEPOSITARY SHARES [OR (B) PRE-FUNDED WARRANTS TO PURCHASE ORDINARY SHARES REPRESENTED BY AMERICAN DEPOSITARY SHARES] (the “Warrant”), issued in the form of uncertificated securities, certifies that, for value received, [_____________] or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after the Issue Date (as defined below) and on or prior to 5:00 p.m. (New York City time) on the Warrant Exercise Deadline (as defined below) but not thereafter (such period of time between the date of the Issue Date and the Warrant Exercise Deadline, the “Exercise Period”), to subscribe for and purchase from ASLAN Pharmaceuticals Limited, an exempted company with limited liability incorporated under the laws of the Cayman Islands (the “Company”), up to [____] Ordinary Shares, nominal or par value $0.01 per share (as subject to a

AMENDED DEVELOPMENT AND LICENSE AGREEMENT By and between ALMIRALL, S.A. and ASLAN PHARMACEUTICALS PTE. LTD. Dated: December 21, 2015
Development and License Agreement • March 26th, 2018 • ASLAN Pharmaceuticals LTD • Pharmaceutical preparations

This AMENDED DEVELOPMENT AND LICENSE AGREEMENT (the “Agreement”), dated as of December 21, 2015 (“Effective Date”), is entered by and between ALMIRALL, S.A. (“ALMIRALL”), a Spanish corporation having its principal offices at Ronda de General Mitre, 151, 08022 Barcelona, Spain, and ASLAN PHARMACEUTICALS Pte. Ltd. (“ASLAN”), a Singapore corporation having its principal offices at 10A Bukit Pasoh Road, Singapore 089824. ALMIRALL and ASLAN shall be referred to individually as a “Party” and collectively as the “Parties”.

LICENSE AGREEMENT
License Agreement • March 26th, 2018 • ASLAN Pharmaceuticals LTD • Pharmaceutical preparations • England and Wales

This License Agreement (this “Agreement”), entered into as of January 3rd, 2018 (the “Effective Date”), is made by and between Array BioPharma Inc., a Delaware corporation, having offices at 3200 Walnut Street, Boulder, Colorado 80301, and ASLAN Pharmaceuticals Pte. Ltd., a Singapore corporation, with offices at 83 Clemenceau Avenue #12-03 UE Square, Singapore 239920.

Contract
License Agreement • April 29th, 2019 • ASLAN Pharmaceuticals LTD • Pharmaceutical preparations

CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS DOCUMENT, MARKED BY […***…], HAS BEEN OMITTED BECAUSE ASLAN PHARMACEUTICALS PTE LTD. HAS DETERMINED THE INFORMATION (I) IS NOT MATERIAL AND (II) WOULD LIKELY CAUSE COMPETITIVE HARM TO ASLAN PHARMACEUTICALS PTE LTD. IF PUBLICLY DISCLOSED.

LICENCE AGREEMENT BETWEEN CSL LIMITED ABN 99 051 588 348 AND ASLAN Pharmaceuticals Pte Ltd
License Agreement • March 26th, 2018 • ASLAN Pharmaceuticals LTD • Pharmaceutical preparations • England

Now, therefore, in consideration of the premises and mutual covenants herein contained, and for other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the Parties hereto agree as follows:

Contract
Warrant Agreement • May 31st, 2024 • ASLAN Pharmaceuticals LTD • Pharmaceutical preparations • New York

THIS WARRANT AND THE SHARES ISSUABLE HEREUNDER HAVE NOT BEEN REGISTERED UNDER THE U.S. SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”), OR THE SECURITIES LAWS OF ANY U.S. STATE AND, EXCEPT AS SET FORTH IN SECTIONS 5.3 AND 5.4 BELOW, MAY NOT BE OFFERED, SOLD, PLEDGED OR OTHERWISE TRANSFERRED UNLESS AND UNTIL REGISTERED UNDER SAID ACT AND LAWS OR, IN THE OPINION OF LEGAL COUNSEL IN FORM AND SUBSTANCE SATISFACTORY TO THE ISSUER, SUCH OFFER, SALE, PLEDGE OR OTHER TRANSFER IS EXEMPT FROM SUCH REGISTRATION.

COLLABORATIVE DEVELOPMENT & COMMERCIALISATION AGREEMENT RELATING TO EBLASAKIMAB IN JAPAN
Collaborative Development & Commercialisation Agreement • April 12th, 2024 • ASLAN Pharmaceuticals LTD • Pharmaceutical preparations • England

ASLAN Pharmaceuticals Pte. Ltd. (“ASLAN”), incorporated and registered in Singapore with company number 201007695N, having its principal offices at 3 Temasek Avenue, Level 18, Centennial Tower, Singapore 039190; and

SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • February 25th, 2021 • ASLAN Pharmaceuticals LTD • Pharmaceutical preparations • New York

This Securities Purchase Agreement (this “Agreement”) is dated as of February 24, 2021 (the “Effective Date”), among ASLAN Pharmaceuticals Limited, an exempted company with limited liability incorporated under the laws of the Cayman Islands (the “Company”), and each purchaser identified on Exhibit A attached hereto (each a “Purchaser” and collectively the “Purchasers”). The Company and the Purchasers are sometimes each referred to herein as a “Party” and collectively as the “Parties.”

WARRANT TO PURCHASE ORDINARY SHARES REPRESENTED BY AMERICAN DEPOSITARY SHARES [OR PRE-FUNDED WARRANTS] ASLAN PHARMACEUTICALS LIMITED
Securities Agreement • February 24th, 2023 • ASLAN Pharmaceuticals LTD • Pharmaceutical preparations

THIS WARRANT TO PURCHASE (A) ORDINARY SHARES REPRESENTED BY AMERICAN DEPOSITARY SHARES [OR (B) PRE-FUNDED WARRANTS TO PURCHASE ORDINARY SHARES REPRESENTED BY AMERICAN DEPOSITARY SHARES] (the “Warrant”), issued in the form of uncertificated securities, certifies that, for value received, [_____________] or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after the Issue Date (as defined below) and on or prior to 5:00 p.m. (New York City time) on the Warrant Exercise Deadline (as defined below) but not thereafter (such period of time between the date of the Issue Date and the Warrant Exercise Deadline, the “Exercise Period”), to subscribe for and purchase from ASLAN Pharmaceuticals Limited, an exempted company with limited liability incorporated under the laws of the Cayman Islands (the “Company”), up to [____] Ordinary Shares, nominal or par value $0.01 per share (as subject to a

AMENDMENT NO. 1 TO WARRANT TO PURCHASE ORDINARY SHARES
Warrant to Purchase Ordinary Shares • July 3rd, 2023 • ASLAN Pharmaceuticals LTD • Pharmaceutical preparations • New York

THIS AMENDMENT NO. 1 TO WARRANT TO PURCHASE ORDINARY SHARES is made this 30th day of June, 2023, by and between K2 HealthVentures Equity Trust LLC (“Holder”) and ASLAN Pharmaceuticals Limited, a Cayman Islands exempted company with registration number 289175 (the “Company”).

AMENDMENT NO. 2 TO THE OPEN MARKET SALE AGREEMENTSM
Open Market Sale Agreement • April 12th, 2024 • ASLAN Pharmaceuticals LTD • Pharmaceutical preparations

This Amendment No. 2 to the Open Market Sale AgreementSM (this “Amendment No. 2”) is entered into as of the date first written above by ASLAN Pharmaceuticals Limited, an exempted company incorporated with limited liability in the Cayman Islands (the “Company”), and Jefferies LLC (“Agent”), which are parties to that certain Open Market Sale AgreementSM, dated October 9, 2020 (the “Original Agreement”), as amended on September 13, 2022 (the “Amendment No. 1” and collectively with the Original Agreement, the “Sale Agreement”). All capitalized terms not defined herein shall have the meanings ascribed to them in the Sale Agreement. The parties, intending to be legally bound, hereby amend the Sale Agreement as follows:

SECOND Amendment to Loan, Guaranty and security agreement
Loan, Guaranty and Security Agreement • December 8th, 2023 • ASLAN Pharmaceuticals LTD • Pharmaceutical preparations • New York

This Second Amendment to Loan, Guaranty, and Security Agreement (this “Amendment”) is entered into this 6th day of December, 2023, by and among (a) ASLAN PHARMACEUTICALS (USA) INC., a Delaware corporation (“Borrower Representative”), ASLAN PHARMACEUTICALS LIMITED, an exempted company incorporated under the laws of the Cayman Islands and each other Person party hereto as a borrower from time to time (“Parent”, and together with Borrower Representative, collectively, “Borrowers”, and each, a “Borrower”), (b) ASLAN PHARMACEUTICALS PTE. LTD., a private company limited by shares formed under the laws of the Republic of Singapore (“ASLAN LTD” and together with each other Person party hereto or any other Loan Documents as a guarantor from time to time, collectively, “Guarantors” and each, a “Guarantor”, and together with Borrowers, collectively, “Loan Parties”, and each, a “Loan Party”), (c) K2 HEALTHVENTURES LLC as a lender, and the other lenders from time to time party hereto (collectively,

AMENDMENT NO. 1 TO THE OPEN MARKET SALE AGREEMENTSM
Open Market Sale Agreement • September 13th, 2022 • ASLAN Pharmaceuticals LTD • Pharmaceutical preparations • New York

This Amendment No. 1 to the Open Market Sale AgreementSM (this “Amendment”) is entered into as of the date first written above by ASLAN Pharmaceuticals Limited, an exempted company incorporated with limited liability in the Cayman Islands (the “Company”), and Jefferies LLC (“Agent”), that are parties to that certain Open Market Sale AgreementSM, dated October 9, 2020 (the “Original Agreement”). All capitalized terms not defined herein shall have the meanings ascribed to them in the Original Agreement. The parties, intending to be legally bound, hereby amend the Original Agreement as follows:

AMENDMENT AGREEMENT No. 1 TO LICENCE AGREEMENT BETWEEN CSL LIMITED ABN 99 051 588 348 AND ASLAN Pharmaceuticals Pte Ltd
Licence Agreement • January 9th, 2019 • ASLAN Pharmaceuticals LTD • Pharmaceutical preparations
FIRST AMENDMENT TO LOAN, GUARANTY AND SECURITY AGREEMENT
Loan, Guaranty and Security Agreement • July 3rd, 2023 • ASLAN Pharmaceuticals LTD • Pharmaceutical preparations • New York

This First Amendment to Loan, Guaranty, and Security Agreement (this “Amendment”) is entered into this 30th day of June, 2023, by and among (a) ASLAN PHARMACEUTICALS (USA) INC., a Delaware corporation (“Borrower Representative”), ASLAN PHARMACEUTICALS LIMITED, an exempted company incorporated under the laws of the Cayman Islands and each other Person party hereto as a borrower from time to time (“Parent”, and together with Borrower Representative, collectively, “Borrowers”, and each, a “Borrower”), (b) ASLAN PHARMACEUTICALS PTE. LTD., a private company limited by shares formed under the laws of the Republic of Singapore (“ASLAN LTD” and together with each other Person party hereto or any other Loan Documents as a guarantor from time to time, collectively, “Guarantors” and each, a “Guarantor”, and together with Borrowers, collectively, “Loan Parties”, and each, a “Loan Party”), (c) K2 HEALTHVENTURES LLC as a lender, and the other lenders from time to time party hereto (collectively, “Le

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Deed of Amendment and Restatement
Licence Agreement • June 17th, 2019 • ASLAN Pharmaceuticals LTD • Pharmaceutical preparations • England
The parties set out in Schedule 1 (as the “Lenders”) and ASLAN Pharmaceuticals Limited (as the “Borrower”) LOAN FACILITY AGREEMENT
Loan Facility Agreement • October 31st, 2019 • ASLAN Pharmaceuticals LTD • Pharmaceutical preparations
PRE-FUNDED WARRANT TO PURCHASE ORDINARY SHARES REPRESENTED BY AMERICAN DEPOSITARY SHARES ASLAN PHARMACEUTICALS LIMITED
Securities Agreement • February 24th, 2023 • ASLAN Pharmaceuticals LTD • Pharmaceutical preparations

THIS PRE-FUNDED WARRANT TO PURCHASE ORDINARY SHARES REPRESENTED BY AMERICAN DEPOSITARY SHARES (this “Warrant”), issued in the form of uncertificated securities, certifies that, for value received, _____________ or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after the date hereof (the “Initial Exercise Date”) until this Warrant is exercised in full (the “Termination Date”) but not thereafter, to subscribe for and purchase from ASLAN Pharmaceuticals Limited, an exempted company with limited liability incorporated under the laws of the Cayman Islands (the “Company”), up to [____] Ordinary Shares, nominal or par value $0.01 per share (as subject to adjustment hereunder, the “Warrant Shares”), represented by [____] American Depositary Shares (“ADSs”), each five (5) Ordinary Shares represented by one (1) ADS, as subject to adjustment hereunder (the “Warrant ADSs”). The purchase p

LOAN, GUARANTY, AND SECURITY AGREEMENT
Loan, Guaranty, and Security Agreement • July 14th, 2021 • ASLAN Pharmaceuticals LTD • Pharmaceutical preparations • New York

This LOAN, GUARANTY, AND SECURITY AGREEMENT (as amended, restated, supplemented or otherwise modified from time to time, this “Agreement”) dated as of July 12, 2021 (the “Closing Date”) is entered into among (a) ASLAN PHARMACEUTICALS (USA) INC., a Delaware corporation (“Borrower Representative”), ASLAN PHARMACEUTICALS LIMITED, an exempted company incorporated under the laws of the Cayman Islands and each other Person party hereto as a borrower from time to time (“Parent”, and together with Borrower Representative, collectively, “Borrowers”, and each, a “Borrower”), (b) ASLAN PHARMACEUTICALS PTE. LTD., a private company limited by shares formed under the laws of the Republic of Singapore (“ASLAN LTD” and together with each other Person party hereto or any other Loan Documents as a guarantor from time to time, collectively, “Guarantors” and each, a “Guarantor”, and together with Borrowers, collectively, “Loan Parties”, and each, a “Loan Party”), (c) K2 HEALTHVENTURES LLC and any other le

The parties set out in Schedule 1 (as the “Lenders”) and ASLAN Pharmaceuticals Limited (as the “Borrower”) LOAN FACILITY AGREEMENT
Loan Facility Agreement • October 31st, 2019 • ASLAN Pharmaceuticals LTD • Pharmaceutical preparations
THIRD Amendment and forbearance to Loan, Guaranty and security agreement
Loan, Guaranty and Security Agreement • May 31st, 2024 • ASLAN Pharmaceuticals LTD • Pharmaceutical preparations • New York

This Third Amendment and Forbearance to Loan, Guaranty, and Security Agreement (this “Amendment”) is entered into this 29th day of May, 2024, by and among (a) ASLAN PHARMACEUTICALS (USA) INC., a Delaware corporation (“Borrower Representative”), ASLAN PHARMACEUTICALS LIMITED, an exempted company incorporated under the laws of the Cayman Islands and each other Person party hereto as a borrower from time to time (“Parent”, and together with Borrower Representative, jointly, severally, and collectively, “Borrowers”, and each, a “Borrower”), (b) ASLAN PHARMACEUTICALS PTE. LTD., a private company limited by shares formed under the laws of the Republic of Singapore (“ASLAN LTD” and together with each other Person party hereto or any other Loan Documents as a guarantor from time to time, collectively, “Guarantors” and each, a “Guarantor”, and together with Borrowers, collectively, “Loan Parties”, and each, a “Loan Party”), (c) K2 HEALTHVENTURES LLC as a lender, and the other lenders from time

Contract
Warrant Agreement • July 14th, 2021 • ASLAN Pharmaceuticals LTD • Pharmaceutical preparations • New York

THIS WARRANT AND THE SHARES ISSUABLE HEREUNDER HAVE NOT BEEN REGISTERED UNDER THE U.S. SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”), OR THE SECURITIES LAWS OF ANY U.S. STATE AND, EXCEPT AS SET FORTH IN SECTIONS 5.3 AND 5.4 BELOW, MAY NOT BE OFFERED, SOLD, PLEDGED OR OTHERWISE TRANSFERRED UNLESS AND UNTIL REGISTERED UNDER SAID ACT AND LAWS OR, IN THE OPINION OF LEGAL COUNSEL IN FORM AND SUBSTANCE SATISFACTORY TO THE ISSUER, SUCH OFFER, SALE, PLEDGE OR OTHER TRANSFER IS EXEMPT FROM SUCH REGISTRATION.

Contract
Loan Facility Agreement • October 31st, 2019 • ASLAN Pharmaceuticals LTD • Pharmaceutical preparations

We refer to the Loan Agreement which we have entered into on today’s date. Terms defined in the Loan Agreement shall have the same meanings herein except where otherwise expressly indicated. This Letter Agreement (“this Agreement”) sets out additional terms to those applying in the Loan Agreement, such additional terms being between the Borrower and the Lender only. This Agreement shall be regarded as supplemental to the Loan Agreement and shall be read and construed in conjunction with the Loan Agreement.

UNIT PURCHASE AGREEMENT
Unit Purchase Agreement • February 24th, 2023 • ASLAN Pharmaceuticals LTD • Pharmaceutical preparations • New York

This Unit Purchase Agreement (this “Agreement”) is dated as of February 24, 2023, by and among ASLAN Pharmaceuticals Limited, an exempted company with limited liability incorporated under the laws of the Cayman Islands (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively the “Purchasers”).

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