Humacyte, Inc. Sample Contracts

ALPHA HEALTHCARE ACQUISITION CORP. UNDERWRITING AGREEMENT
Underwriting Agreement • September 22nd, 2020 • Alpha Healthcare Acquisition Corp. • Blank checks • New York

Alpha Healthcare Acquisition Corp., a Delaware corporation (the “Company”), hereby confirms its agreement with Oppenheimer & Co. Inc. (the “Representative”), as representative of the several underwriters named on Schedule A hereto (the “Underwriters” or, each underwriter individually, an “Underwriter”), as follows:

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WARRANT AGREEMENT
Warrant Agreement • September 22nd, 2020 • Alpha Healthcare Acquisition Corp. • Blank checks • New York

THIS WARRANT AGREEMENT (this “Agreement”), dated as of September 17, 2020, is by and between Alpha Healthcare Acquisition Corp., a Delaware corporation (the “Company”), and Continental Stock Transfer & Trust Company, a New York corporation, as warrant agent (in such capacity, the “Warrant Agent”).

INVESTMENT MANAGEMENT TRUST AGREEMENT
Investment Management Trust Agreement • September 22nd, 2020 • Alpha Healthcare Acquisition Corp. • Blank checks • New York

This Investment Management Trust Agreement (this “Agreement”) is made effective as of September 17, 2020, by and between Alpha Healthcare Acquisition Corp., a Delaware corporation (the “Company”), and Continental Stock Transfer & Trust Company, a New York corporation (the “Trustee”).

Alpha Healthcare Acquisition Corp. New York, NY 10036
Alpha Healthcare Acquisition Corp. • August 4th, 2020 • New York

This agreement (the “Agreement”) is entered into on July 20, 2020 by and between AHAC Sponsor, LLC, a Delaware limited liability company (the “Subscriber” or “you”), and Alpha Healthcare Acquisition Corp., a Delaware corporation (the “Company,” “we” or “us”). Pursuant to the terms hereof, the Company hereby accepts the offer the Subscriber has made to purchase 2,875,000 shares of Class B common stock, $0.0001 par value per share (the “Shares”), up to 375,000 of which are subject to forfeiture by you if the underwriters of the initial public offering (“IPO”) of units (“Units”) of the Company, do not fully exercise their over-allotment option (the “Over-allotment Option”). The Company and the Subscriber’s agreements regarding such Shares are as follows:

September 17, 2020
Letter Agreement • September 22nd, 2020 • Alpha Healthcare Acquisition Corp. • Blank checks • New York

This letter (this “Letter Agreement”) is being delivered to you in accordance with the Underwriting Agreement (the “Underwriting Agreement”) entered into by and among Alpha Healthcare Acquisition Corp., a Delaware corporation (the “Company”), and Oppenheimer & Co. Inc., as representative (the “Representative”) of the several underwriters (each, an “Underwriter” and collectively, the “Underwriters”), relating to an underwritten initial public offering (the “Public Offering”), of 11,500,000 of the Company’s units (including up to 1,500,000 units that may be purchased to cover over-allotments, if any) (the “Units”), each comprised of one share of the Company’s Class A common stock, par value $0.0001 per share (the “Common Stock”), and one-half of one redeemable warrant. Each whole warrant (each, a “Warrant”) entitles the holder thereof to purchase one share of Common Stock at a price of $11.50 per share, subject to adjustment. The Units will be sold in the Public Offering pursuant to a re

FORM OF INDEMNITY AGREEMENT
Form of Indemnity Agreement • September 1st, 2020 • Alpha Healthcare Acquisition Corp. • Blank checks • Delaware

THIS INDEMNITY AGREEMENT (this “Agreement”) is made as of _________, 2020, by and between Alpha Healthcare Acquisition Corp., a Delaware corporation (the “Company”), and ___________ (“Indemnitee”).

13,400,000 Shares HUMACYTE, INC. Common Stock UNDERWRITING AGREEMENT
Underwriting Agreement • March 4th, 2024 • Humacyte, Inc. • Biological products, (no disgnostic substances) • New York
OPEN MARKET SALE AGREEMENTSM
Humacyte, Inc. • September 1st, 2022 • Biological products, (no disgnostic substances) • New York

Humacyte, Inc., a Delaware corporation (the “Company”), proposes, subject to the terms and conditions stated herein, to issue and sell from time to time through Jefferies LLC, as sales agent and/or principal (the “Agent”), shares of the Company’s common stock, par value $0.0001 per share (the “Common Shares”), having an aggregate offering price of up to $80,000,000 on the terms set forth in this agreement (this “Agreement”).

FORM OF REGISTRATION RIGHTS AGREEMENT
Form of Registration Rights Agreement • September 22nd, 2020 • Alpha Healthcare Acquisition Corp. • Blank checks • New York

THIS REGISTRATION RIGHTS AGREEMENT (this “Agreement”), dated as of September 17, 2020, is made and entered into by and among Alpha Healthcare Acquisition Corp., a Delaware corporation (the “Company”) and AHAC Sponsor LLC, a Delaware limited liability company (the “Sponsor”), Oppenheimer & Co. Inc. (“Oppenheimer”) and Northland Securities Inc. (“Northland,” and together with the Sponsor, Oppenheimer and any person or entity who hereafter becomes a party to this Agreement pursuant to Section 5.2 of this Agreement, a “Holder” and collectively the “Holders”).

LEASE AGREEMENT
Lease Agreement • March 23rd, 2021 • Alpha Healthcare Acquisition Corp. • Blank checks • North Carolina

THIS LEASE AGREEMENT (this “Lease”) is made this 31st day of December, 2015, between ARE-NC REGION NO. 5, LLC, a Delaware limited liability company (“Landlord”), and HUMACYTE, INC., a North Carolina corporation (“Tenant”).

FORM OF INDEMNITY AGREEMENT
Indemnity Agreement • July 1st, 2021 • Alpha Healthcare Acquisition Corp. • Biological products, (no disgnostic substances) • Delaware

THIS INDEMNITY AGREEMENT (this “Agreement”) dated as of _______________, is made by and between Humacyte, INC., a Delaware corporation (the “Company”), and _________________ (“Indemnitee”).

SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • October 7th, 2024 • Humacyte, Inc. • Biological products, (no disgnostic substances) • New York

This Securities Purchase Agreement (this “Agreement”) is dated as of October 4, 2024, between Humacyte, Inc., a Delaware corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively the “Purchasers”).

UNIT SUBSCRIPTION AGREEMENT
Unit Subscription Agreement • September 22nd, 2020 • Alpha Healthcare Acquisition Corp. • Blank checks • New York

This UNIT SUBSCRIPTION AGREEMENT (this “Agreement”) is made as of September 17, 2020, by and between Alpha Healthcare Acquisition Corp., a Delaware corporation (the “Company”), and Oppenheimer & Co. Inc. (the “Subscriber”).

LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • June 14th, 2021 • Alpha Healthcare Acquisition Corp. • Biological products, (no disgnostic substances) • New York

The undersigned, being an Authorized Signer of Humacyte, Inc., a Delaware corporation (“Borrower”), does hereby certify to (a) SILICON VALLEY BANK, a California corporation (“SVB”), in its capacity as administrative agent and collateral agent (“Agent”), (b) SVB, as a lender, (c) SVB INNOVATION CREDIT FUND VIII, L.P., a Delaware limited partnership (“SVB Capital”), as a lender (SVB and SVB Capital and each of the other “Lenders” from time to time a party hereto are referred to herein collectively as the “Lenders” and each individually as a “Lender”) in connection with that certain Loan and Security Agreement dated as of March 30, 2021, by and among Borrower, Agent and the Lenders from time to time party thereto (the “Loan Agreement”; with other capitalized terms used below having the meanings ascribed thereto in the Loan Agreement) that:

UNIT SUBSCRIPTION AGREEMENT
Unit Subscription Agreement • September 22nd, 2020 • Alpha Healthcare Acquisition Corp. • Blank checks • New York

This UNIT SUBSCRIPTION AGREEMENT (this “Agreement”) is made as of September 17, 2020, by and between Alpha Healthcare Acquisition Corp., a Delaware corporation (the “Company”), having its principal place of business at 1177 Avenue of the Americas, 5th Floor, New York, New York 10036, and AHAC Sponsor LLC, a Delaware limited liability company (the “Subscriber”), having its principal place of business at 1177 Avenue of the Americas, 5th Floor, New York, New York 10036.

EXCLUSIVE LICENSE AGREEMENT
Exclusive License Agreement • June 14th, 2021 • Alpha Healthcare Acquisition Corp. • Biological products, (no disgnostic substances) • Connecticut

THIS AGREEMENT (this “Agreement”) by and between YALE UNIVERSITY, a corporation organized and existing under and by virtue of a charter granted by the general assembly of the Colony and State of Connecticut and located in New Haven, Connecticut (“YALE”), and Humacyte, Inc. a corporation organized and existing under the laws of the State of Delaware and with principal offices located at 2525 E. NC Highway 54 in Durham, NC (“LICENSEE”) is effective as of August 25, 2019 (“EFFECTIVE DATE”).

INCENTIVE STOCK OPTION AGREEMENT Under the HUMACYTE, INC. 2005 STOCK OPTION PLAN
Incentive Stock Option Agreement • March 23rd, 2021 • Alpha Healthcare Acquisition Corp. • Blank checks

THIS INCENTIVE STOCK OPTION AGREEMENT (this “Agreement”) is made as of the ___ day of _____, 200_ (the “Grant Date”), by and between Humacyte, Inc. (the “Company”) and ___________ (the “Participant”).

HUMACYTE, INC. NONQUALIFIED STOCK OPTION AGREEMENT Under the HUMACYTE, INC.
Nonqualified Stock Option Agreement • March 23rd, 2021 • Alpha Healthcare Acquisition Corp. • Blank checks

THIS NONQUALIFIED STOCK OPTION AGREEMENT (this “Agreement”) is made as of the __ day of _____, 200_ (the “Grant Date”), by and between Humacyte, Inc. (the “Company”) and ___________ (the “Participant”).

SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • November 14th, 2024 • Humacyte, Inc. • Biological products, (no disgnostic substances) • New York

This Securities Purchase Agreement (this “Agreement”) is dated as of November 13, 2024, between Humacyte, Inc., a Delaware corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively the “Purchasers”).

Alpha Healthcare Acquisition Corp.
Letter Agreement • September 22nd, 2020 • Alpha Healthcare Acquisition Corp. • Blank checks • New York

This letter agreement by and between Alpha Healthcare Acquisition Corp. (the “Company”) and Constellation Alpha Holdings LLC (“Constellation”), dated as of the date hereof, will confirm our agreement that, commencing on the date the securities of the Company are first listed on The Nasdaq Capital Market (the “Listing Date”), pursuant to a Registration Statement on Form S-1 and prospectus filed with the U.S. Securities and Exchange Commission (the “Registration Statement”) and continuing until the earlier of the consummation by the Company of an initial business combination or the Company’s liquidation (in each case as described in the Registration Statement) (such earlier date hereinafter referred to as the “Termination Date”):

SUBSCRIPTION AGREEMENT
Subscription Agreement • March 23rd, 2021 • Alpha Healthcare Acquisition Corp. • Blank checks • New York

This Subscription Agreement (this “Subscription Agreement”) is being entered into in connection with the proposed business combination (the “Transaction”) between Alpha Healthcare Acquisition Corp., a Delaware corporation (“Alpha”), and Humacyte, Inc., a Delaware corporation (the “Company”), pursuant to a merger agreement to be entered into among Alpha, the Company, and the other parties thereto (the “Transaction Agreement”).

Contract
Alpha Healthcare Acquisition Corp. • June 14th, 2021 • Biological products, (no disgnostic substances) • New York

THIS WARRANT AND THE SHARES ISSUABLE HEREUNDER HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”), OR THE SECURITIES LAWS OF ANY STATE AND, EXCEPT AS SET FORTH IN SECTIONS 6.3 AND 6.4 BELOW, MAY NOT BE OFFERED, SOLD, PLEDGED OR OTHERWISE TRANSFERRED UNLESS AND UNTIL REGISTERED UNDER SAID ACT AND LAWS OR IN FORM AND SUBSTANCE SATISFACTORY TO THE COMPANY, SUCH OFFER, SALE, PLEDGE OR OTHER TRANSFER IS EXEMPT FROM SUCH REGISTRATION.

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COMMON STOCK PURCHASE WARRANT Humacyte, Inc.
Common Stock Purchase Warrant • October 7th, 2024 • Humacyte, Inc. • Biological products, (no disgnostic substances)

THIS COMMON STOCK PURCHASE WARRANT (the “Warrant”) certifies that, for value received, Armistice Capital Master Fund Ltd. or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after the Issue Date (the “Initial Exercise Date”) and on or prior to 5:00 p.m. (New York City time) on that date that is [1,640][180] days from the Issue Date (the “Termination Date”) but not thereafter, to subscribe for and purchase from Humacyte, Inc., a Delaware corporation (the “Company”), up to [ ] shares (as subject to adjustment hereunder, the “Warrant Shares”) of Common Stock. The purchase price of one share of Common Stock under this Warrant shall be equal to the Exercise Price, as defined in Section 2(b).

EXECUTIVE EMPLOYMENT AGREEMENT
Executive Employment Agreement • March 23rd, 2021 • Alpha Healthcare Acquisition Corp. • Blank checks • North Carolina

This Executive Employment Agreement (“Agreement”) is made and entered into by Humacyte, Inc. (“Humacyte” or the “Company”) and Jeffrey Lawson, M.D. (hereinafter “Executive”) effective June 19, 2018.

EXECUTIVE EMPLOYMENT AGREEMENT
Executive Employment Agreement • March 24th, 2023 • Humacyte, Inc. • Biological products, (no disgnostic substances) • North Carolina

This Executive Employment Agreement (“Agreement”) is made and entered into by Humacyte, Inc. (“Humacyte” or the “Company”) and Dale Sander (hereinafter “Executive”) dated May 18, 2021 (the “Effective Date”).

FORM OF UNIT SUBSCRIPTION AGREEMENT
Form of Unit Subscription Agreement • September 1st, 2020 • Alpha Healthcare Acquisition Corp. • Blank checks • New York

This UNIT SUBSCRIPTION AGREEMENT (this “Agreement”) is made as of [●], 2020, by and between Alpha Healthcare Acquisition Corp., a Delaware corporation (the “Company”), having its principal place of business at 1177 Avenue of the Americas, 5th Floor, New York, New York 10036, and AHAC Sponsor LLC, a Delaware limited liability company (the “Subscriber”), having its principal place of business at 1177 Avenue of the Americas, 5th Floor, New York, New York 10036.

EXECUTIVE EMPLOYMENT AGREEMENT
Executive Employment Agreement • March 24th, 2023 • Humacyte, Inc. • Biological products, (no disgnostic substances) • North Carolina

This Executive Employment Agreement (“Agreement”) is made and entered into by Humacyte, Inc. (“Humacyte” or the “Company”) and Shamik Parikh, MD (hereinafter “Executive”) on January 13, 2022. This Agreement will become effective upon Executive’s commencement of employment with the Company (such date, the “Effective Date”), April 4, 2022.

Distribution Agreement by and between Fresenius Medical Care Holdings, Inc. and Humacyte, Inc. June 25, 2018
Distribution Agreement • March 23rd, 2021 • Alpha Healthcare Acquisition Corp. • Blank checks • Delaware

THIS DISTRIBUTION AGREEMENT (this “Agreement”), entered into as of June 25, 2018 (the “Effective Date”), is entered into by and among Fresenius Medical Care Holdings, Inc., a corporation organized and existing under the Laws of the State of New York (“Fresenius”), and Humacyte, Inc., a corporation organized and existing under the Laws of the State of Delaware (“Humacyte”). Fresenius and Humacyte are referred to in this Agreement individually as a “Party” and collectively as the “Parties.”

FIRST AMENDMENT TO DISTRIBUTION AGREEMENT
Distribution Agreement • March 23rd, 2021 • Alpha Healthcare Acquisition Corp. • Blank checks

This First Amendment to Distribution Agreement, made as of this 2nd day of October, 2019 (the “Effective Date”), is by and between Fresenius Medical Care Holdings, Inc. (“Fresenius”) and Humacyte, Inc. (“Humacyte”) (collectively, the “Parties”).

REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • September 25th, 2024 • Humacyte, Inc. • Biological products, (no disgnostic substances) • Delaware

THIS REGISTRATION RIGHTS AGREEMENT (this “Agreement”), dated as of September 24, 2024, is entered into by and between HUMACYTE, INC., a Delaware corporation (the “Company”), and LINCOLN PARK CAPITAL FUND, LLC, an Illinois limited liability company (together with its permitted assigns, the “Investor”). Capitalized terms used herein and not otherwise defined herein shall have the respective meanings set forth in the Purchase Agreement by and between the parties hereto, dated as of the date hereof (as amended, restated, supplemented or otherwise modified from time to time, the “Purchase Agreement”).

EXECUTIVE SEPARATION AND RELEASE AGREEMENT
Executive Separation and Release Agreement • March 29th, 2022 • Humacyte, Inc. • Biological products, (no disgnostic substances) • North Carolina

This Executive Separation and Release Agreement (“Agreement”) is entered into by and between Humacyte, Inc. (“Humacyte”) and Jeffrey Lawson, M.D., Ph.D. (“Executive”), effective as of the date signed by Executive (the “Effective Date”). Humacyte and Executive are collectively referred to as the “Parties.”

CONSULTING AGREEMENT
Consulting Agreement • June 14th, 2021 • Alpha Healthcare Acquisition Corp. • Biological products, (no disgnostic substances) • North Carolina

THIS CONSULTING AGREEMENT (the “Agreement”) is made as of May 17, 2021 by and between Humacyte, Inc., a Delaware corporation (the “Company”), and Douglas Blankenship (“Consultant” or “Blankenship”).

SUPPLY AGREEMENT
Supply Agreement • March 23rd, 2021 • Alpha Healthcare Acquisition Corp. • Blank checks

This Supply Agreement (this “Agreement”) is entered into as of January 9, 2014 (the “Effective Date”), by and between Humacyte, Inc., a North Carolina corporation having an address at 7020 Kit Creek Road, P.O. Box 12695, Durham, NC 27709 (“Purchaser”) and SeraCare Life Sciences, Inc., a Delaware corporation having its principal place of business at 37 Birch Street, Milford, Massachusetts 01757 (“Supplier”). Purchaser and Supplier are sometimes referred to herein individually as a “Party” or collectively as the “Parties.”

INCENTIVE STOCK OPTION AGREEMENT Under the HUMACYTE, INC.
Incentive Stock Option Agreement • March 23rd, 2021 • Alpha Healthcare Acquisition Corp. • Blank checks

THIS INCENTIVE STOCK OPTION AGREEMENT (this “Agreement”) is made as of the ___ day of ________, 201__ (the “Grant Date”), by and between Humacyte, Inc. (the “Company”) and _______________ (the “Participant”).

COMMON STOCK PURCHASE WARRANT Humacyte, Inc.
Common Stock Purchase Warrant • November 14th, 2024 • Humacyte, Inc. • Biological products, (no disgnostic substances)

THIS COMMON STOCK PURCHASE WARRANT (the “Warrant”) certifies that, for value received, Woodline Master Fund LP or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after the Issue Date (the “Initial Exercise Date”) and on or prior to 5:00 p.m. (New York City time) on that date that is [1,640][180] days from the Issue Date (the “Termination Date”) but not thereafter, to subscribe for and purchase from Humacyte, Inc., a Delaware corporation (the “Company”), up to [ ] shares (as subject to adjustment hereunder, the “Warrant Shares”) of Common Stock. The purchase price of one share of Common Stock under this Warrant shall be equal to the Exercise Price, as defined in Section 2(b).

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