0001047469-03-020870 Sample Contracts

March 13, 2003
Severance Agreement • June 10th, 2003 • Pharsight Corp • Services-prepackaged software • California

As we have discussed, Pharsight Corporation (“Pharsight” or the “Company”) is offering you continued employment through April 30, 2003 and severance benefits under the terms and conditions set forth below (the “Agreement”).

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THIRD AMENDMENT TO THE LEASE
Lease Agreement • June 10th, 2003 • Pharsight Corp • Services-prepackaged software
March 20, 2003
Promotion Agreement • June 10th, 2003 • Pharsight Corp • Services-prepackaged software

As we have discussed with you, Pharsight Corporation (the “Company”) in conjunction with Execustaff, Inc., is pleased to offer you a promotion to the position of Chief Executive Officer under the terms set forth in this letter. Your promotion and the terms set forth in this letter agreement (“Agreement”) shall be effective as of February 13, 2003.

March 6, 2003
Promotion Agreement • June 10th, 2003 • Pharsight Corp • Services-prepackaged software

As we have discussed with you, Pharsight Corporation (the “Company”) in conjunction with Execustaff, Inc., is pleased to offer you a promotion to the position of Chief Financial Officer under the terms set forth in this letter. Your promotion and the terms set forth in this letter agreement (“Agreement”) shall be effective as of February 12, 2003.

LOAN MODIFICATION AGREEMENT
Loan Modification Agreement • June 10th, 2003 • Pharsight Corp • Services-prepackaged software

This Loan Modification Agreement is entered into as of May 28, 2003, by and between Pharsight Corporation (the “Borrower”) and Silicon Valley Bank (“Bank”).

February 11, 2003
Separation Agreement • June 10th, 2003 • Pharsight Corp • Services-prepackaged software • California

This letter sets forth the substance of the separation agreement (the “Agreement”) that Pharsight Corporation (the “Company”) is offering to you to aid in your employment transition.

AMENDMENT NO. 1 TO PREFERRED STOCK AND WARRANT PURCHASE AGREEMENT AND WAIVER
Preferred Stock and Warrant Purchase Agreement • June 10th, 2003 • Pharsight Corp • Services-prepackaged software • California

This Amendment No. 1 to Preferred Stock and Warrant Purchase Agreement and Waiver (this “Amendment”) is entered into as of this 13th day of February, 2003, by and among Pharsight Corporation, a Delaware corporation (the “Company”), and each of those persons and entities, severally and not jointly, listed as a Purchaser on the Schedule of Purchasers attached as Exhibit A hereto (each, a “Purchaser” and collectively, the “Purchasers”).

May 22, 2003 Alloy Ventures
Waiver of Filing Post-Effective Amendment on Form S-1 • June 10th, 2003 • Pharsight Corp • Services-prepackaged software
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