0001047469-98-010647 Sample Contracts

Exhibit 10.22 AMENDMENT TO PROMISSORY NOTE This Amendment to Promissory Note (this "Amendment") is entered into as of this 23th day of December, 1997 by and between Cubist Pharmaceuticals, Inc., a Delaware Corporation, (the "Payee") and Scott M....
Promissory Note • March 20th, 1998 • Cubist Pharmaceuticals Inc • Pharmaceutical preparations

This Amendment to Promissory Note (this "Amendment") is entered into as of this 23th day of December, 1997 by and between Cubist Pharmaceuticals, Inc., a Delaware Corporation, (the "Payee") and Scott M. Rocklage (the "Maker").

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Exhibit 10.33 CUBIST PHARMACEUTICALS, INC. 24 Emily Street Cambridge, MA 02139 January 9, 1998 Mr. Mark P. Carthy 21 Stone Road Belmont, Massachusetts 02178
Cubist Pharmaceuticals Inc • March 20th, 1998 • Pharmaceutical preparations • Massachusetts

Reference is hereby made to that certain Letter Agreement, dated as of May 19, 1997 (the "Agreement"), between you and Cubist Pharmaceuticals, Inc., a Delaware corporation (the "Company"), pursuant to which you exercised your stock option to purchase 10,000 shares (the "Shares") of the Company's common stock, $.001 par value per share, at an exercise price of $8.00 per share, and you paid for the Shares by delivering to the Company a Secured Promissory Note in the principal amount of $80,000 (the "Note"), which the Company agreed to forgive over time. Capitalized terms which are not defined herein shall have the same meanings as ascribed to such terms in the Agreement.

CONFIDENTIAL TREATMENT RESEARCH COLLABORATION AND LICENSE AGREEMENT
Confidential Treatment Research Collaboration and License Agreement • March 20th, 1998 • Cubist Pharmaceuticals Inc • Pharmaceutical preparations • Massachusetts
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