0001104659-22-086733 Sample Contracts

PROTAGONIST THERAPEUTICS, INC., Issuer AND [TRUSTEE], Trustee INDENTURE Dated as of [●], 202[●] Subordinated Debt Securities INDENTURE
Indenture • August 5th, 2022 • Protagonist Therapeutics, Inc • Pharmaceutical preparations • New York

INDENTURE, dated as of [●], 202 , among PROTAGONIST THERAPEUTICS, INC., a Delaware corporation (the “Company”), and [TRUSTEE] as trustee (the “Trustee”):

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OPEN MARKET SALE AGREEMENTSM
Open Market Sale Agreement • August 5th, 2022 • Protagonist Therapeutics, Inc • Pharmaceutical preparations • New York

Protagonist Therapeutics, Inc., a Delaware corporation (the “Company”), proposes, subject to the terms and conditions stated herein, to issue and sell from time to time through Jefferies LLC, as sales agent and/or principal (the “Agent”), shares of the Company’s common stock, par value $0.00001 per share (the “Common Shares”), having an aggregate offering price of up to $100,000,000 on the terms set forth in this agreement (this “Agreement”).

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