0001193125-03-055968 Sample Contracts

4/th/ AMENDMENT relating to a development agreement between LION bioscience AG and Bayer AG dated 13/th/ October, 2000 CONTENTS
Agreement • September 30th, 2003 • Lion Bioscience Ag • Services-commercial physical & biological research
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Lease • September 30th, 2003 • Lion Bioscience Ag • Services-commercial physical & biological research • California
AMENDMENT NO. 2 to the BASIC AGREEMENT
Basic Agreement • September 30th, 2003 • Lion Bioscience Ag • Services-commercial physical & biological research
Amendment to the Basic Agreement of June 17/th//18/th/ 1999
Lion Bioscience Ag • September 30th, 2003 • Services-commercial physical & biological research

Due to the good experiences made in the past BAYER and LION agree to change and amend the Basic Agreement of June 17/th//18/th/ 1999 to the following effect:

Amendment to the Basic Agreement of June 17/th//18/th/ 1999
Lion Bioscience Ag • September 30th, 2003 • Services-commercial physical & biological research

Due to the successful co-operation of LION and BAYER during the first 2 years of the contractual period the parties agree to amend the Basic Agreement of June 17/th//18/th/ 1999 as follows:

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