Familial adenomatous polyposis definition

Familial adenomatous polyposis or “FAP” means an inherited colorectal cancer syndrome and accounts for 1 percent of all cases of colorectal cancer. “Familial” means FAP runs in families; “adenomatous” means the type of polyps detected in the colon and small intestine that may become cancerous; and “polyposis” means the condition of having multiple colon polyps. The gene for FAP is on the long arm of chromosome 5 and is called the APC gene.

Examples of Familial adenomatous polyposis in a sentence

  • Familial adenomatous polyposis patients have high levels of arachidonic acid and docosa- hexaenoic acid and low levels of linoleic acid and alpha- linolenic acid in serum phospholipids.

  • Familial adenomatous polyposis (FAP) is an inherited disorder characterized by many adenomatous polyps (growths) in the colon as early as their teenage years.

  • Familial adenomatous polyposis in particular isa serious condition; virtually all patients will develop colon cancer if it is left untreated.

  • Familial adenomatous polyposis (FAP): frequency, penetrance, and mutation rate.

  • Creighton UniversitySchool of Medicine, Omaha, NE.Background: Familial adenomatous polyposis (FAP) is caused by germ line mutations in APC gene.

  • Familial adenomatous polyposis: ileo-anal pouch versus ileo-rectal anastomosis.

  • Familial adenomatous polyposis (FAP) (Half, Bercovich, & Rozen, 2009) and Gardner syndrome (Juhn & Khachemoune, 2010) are both as well strongly associated with this type of cancer.

  • There is hardly any mechanism of securely distributing keys in an insecure environment on line.

  • Familial adenomatous polyposis (FAP), which is the most common polyposis disorder, affects less than 1% of all CRC patients4,6.Although the exact genetic mechanisms underlying hereditary and sporadic CRC differ, the CRC development can be divided into two distinct pathways; chromosomal instability (CIN) and microsatellite instability (MSI).

  • Familial adenomatous polyposis (FAP) is an autosomal dominant disorder with a germline mutation in the tumor suppressor gene, Adenomatous Polyposis Coli (APC), with an estimated prevalence of 1 out of 5.000 – 7.000 births (1).

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