Pro-drug definition

Pro-drug as used herein means a compound which (i) is designed to overcome pharmacokinetic barriers to delivery of a parent compound, (ii) is an inactive or less active form of the parent compound; and (iii) is converted back to the parent compound after the pharmacokinetic barrier is overcome.
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Pro-drug means any drug that changes structure such that the active ingredient after administration into a patient is Paclitaxel as evidenced by a mutually agreed upon test or standard.
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Pro-drug means a compound where one or more phosphate groups are attached (by one or more bonds) to one or more phenol groups of a COMBRETASTATIN compound, and such phosphate group(s) can be cleaved by a phosphatase enzyme.
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More Definitions of Pro-drug

Pro-drug means any inert component added to […***…] in order to improve the delivery, bioavailability, absorption, metabolism or excretion of […***…] in the human body.
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Related to Pro-drug

  • Prescription drug means any drug required by federal law or regulation to be dispensed only

  • Covered drug means any prescription drug that:

  • Generic Drug means any Prescription Drug approved by the FDA that has the same bio-equivalency as a specific Brand Name Drug.

  • Clinical laboratory means a facility for the microbiological, serological, chemical, hematological, radiobioassay, cytological, immunohematological, pathological, or other examination of materials derived from the human body for the purpose of providing information for the diagnosis, prevention, or treatment of a disease or assessment of a medical condition.

  • FDA means the United States Food and Drug Administration and any successor agency thereto.

  • Brand Name Drug means a Prescription Drug that has been given a name by a manufacturer or distributor to distinguish it as produced or sold by a specific manufacturer or distributor and may be used and protected by a trademark.

  • New Drug Application or “NDA” means a New Drug Application filed with the FDA as described in 21 C.F.R. § 314, a Biological License Application (BLA) pursuant to 21 C.F.R. § 601.2, or any equivalent or any corresponding application for Regulatory Approval (not including pricing and reimbursement approval) in any country or regulatory jurisdiction other than the United States.

  • Legend drug or "prescription drug" means any drug or device that has been determined to be unsafe for self- medication or any drug or device that bears or is required to bear the legend:

  • Drug means (i) articles or substances recognized in the official United States Pharmacopoeia

  • FFDCA means the United States Federal Food, Drug, and Cosmetic Act, 21 U.S.C. § 301 et seq., as amended from time to time, together with any rules, regulations and requirements promulgated thereunder (including all additions, supplements, extensions, and modifications thereto).

  • Bulk drug substance means any substance that is represented for use, and that, when used in the

  • FDCA shall have the meaning ascribed to such term in Section 3.1(hh).

  • PDMA means the Prescription Drug Marketing Act, as amended, and the rules and regulations promulgated thereunder.

  • medicinal product means any substance or combination of substances presented for treating or preventing disease in human beings or animals and any substance or combination of substances which may be administered to human beings or animals with a view to making a medical diagnosis or to restoring, correcting or modifying physiological functions in humans or in animals;

  • Legend drugs means any drugs which are required by state

  • Nonprescription drugs means nonnarcotic medicines or drugs which may be sold without a prescription and are prepackaged and labeled for use by the consumer in accordance with the requirements of the statutes and regulations of this state and the federal government;