Small Interfering RNA definition

Small Interfering RNA or “siRNA” means a double-stranded ribonucleic acid (RNA) composition designed to act primarily through an RNA Interference Mechanism that consists of either (a) two separate oligomers of native or chemically modified RNA that are hybridized to one another along a substantial portion of their lengths, or (b) a single oligomer of native or chemically modified RNA that is hybridized to itself by self-complementary base-pairing along a substantial portion of its length to form a hairpin.
Sample 1Sample 2Sample 3
Small Interfering RNA or “siRNA” means a double-stranded ribonucleic acid (RNA) composition designed to act primarily through an RNA Interference Mechanism that
Sample 1

Examples of Small Interfering RNA in a sentence

  • An Amphiphilic Dendrimer for Effective Delivery of Small Interfering RNA and Gene Silencing in Vitro in Vivo.

  • Phase I Clinical Trial of SYL040012, A Small Interfering RNA Targeting β-Adrenergic Receptor 2, for Lowering Intraocular Pressure.

  • Dr. María José Alonso full professor of Biopharmaceutics and Pharmaceutical Technology at the University of Santiago de Compostela (USC) (SP) 17.00 Exploring bio‐inspired Nanocomposites of Nanogels and Pulmonary Surfactant for Small Interfering RNA Delivery to the LungDr. Koen Raemdonck FWO Postdoctoral Researcher, Lab of General Biochemistry and Physical Pharmacy, Ghent Research Group on Nanomedicines, Ghent (B)17.15 Mucus Permeating Nanocarriers for the Delivery of ProteinsProf.

  • These players’ diets may not be adequate for players to achieve peak performance.5Title: Small Interfering RNA as the Silver Bullet for CancerPresenter(s): Rebecca SommerAdvisor: Dr. Vaughn Gehle & Pam Sanders, BiologyAbstract: One in 200 people are diagnosed with cancer each year in the U.S. Treatments are often non-specific with significant side effects.

  • Intravaginal Gene Silencing Using Biodegradable Polymer Nanoparticles Densely Loaded with Small- Interfering RNA.

  • Shizawa Y, Takeuchi M, Tamano K, Ibaraki H, Seta Y, Takashima, Okada H,Topical Anti-Nuclear Factor-Kappa B Small Interfering RNA with Functional Peptides Containing Sericin-Based Hydrogel for Atopic Dermatitis.

  • Multivalent Cyclic RGD Conjugates for Targeted Delivery of Small Interfering RNA.

  • The purpose of the molecules is to allow the passage of genetic sequences into the cell, which are designed to "decrease" the expression of specific genes that encode the proteins involved in disease processes (siRNA Small Interfering RNA).

  • Differentially Charged Hollow Core/Shell Lipid–Polymer–Lipid Hybrid Nanoparticles for Small Interfering RNA Delivery.

  • Delivery of Small Interfering RNA to Inhibit Vascular Endothelial Growth Factor in Zebrafish Using Natural Brain Endothelia Cell-secreted Exosome Nanovesicles for the Treatment of Brain Cancer, The AAPS Journal 2016 Nov.

Related to Small Interfering RNA

  • harmful interference means interference which endangers the functioning of a radio navigation service or of other safety services or which otherwise seriously degrades, obstructs or repeatedly interrupts a radio communications service operating in accordance with the applicable international, Union or national regulations;

  • Disruptive student means an elementary or secondary student under the age of 21 who is substantially disruptive of the educational process or substantially interferes with the teacher's authority over the classroom.

  • Area of concern or “AOC” shall mean any area that has had a probable release of a hazardous waste or hazardous constituents and that is determined by the Department to pose a current or potential threat to human health or the environment.

  • Compound of Concern means a contaminant that, based on generally available information, may be emitted to the atmosphere in a quantity from any source at the Facility that is significant either in comparison to the relevant Ministry Point of Impingement Limit or if a Ministry Point of Impingement Limit is not available for the compound then, based on generally available toxicological information, the compound has the potential to cause an adverse effect as defined by the EPA at a Point of Impingement.

  • Company Technology means all Technology used in or necessary for the conduct of the business of the Company or any of its Subsidiaries, or owned or held for use by the Company or any of its Subsidiaries.

  • Interfere means any action or inaction that interrupts, interferes, delays or damages Project work.

  • Competing Activities means the same or similar services as Xxxxxx Xxx Ltd is providing to the Restaurant under this Agreement or other activities having a similar purpose.

  • End-use means the light, heat, cooling, refrigeration, motor drive, microwave energy, video or audio signal, computer processing, electrolytic process, or other useful work produced by equipment using electricity.

  • Restricted business operations means business operations in Sudan that include power production activities, mineral extraction activities, oil-related activities, or the production of military equipment, as those terms are defined in the Sudan Accountability and Divestment Act of 2007 (Pub. L. 110-174). Restricted business operations do not include business operations that the person (as that term is defined in Section 2 of the Sudan Accountability and Divestment Act of 2007) conducting the business can demonstrate—

  • Customer Technology means Customer's proprietary technology, including Customer's Internet operations design, content, software tools, hardware designs, algorithms, software (in source and object forms), user interface designs, architecture, class libraries, objects and documentation (both printed and electronic), know-how, trade secrets and any related intellectual property rights throughout the world (whether owned by Customer or licensed to Customer from a third party) and also including any derivatives, improvements, enhancements or extensions of Customer Technology conceived, reduced to practice, or developed during the term of this Agreement by Customer.

  • Substantial business relationship means the extent of a business relationship necessary under applicable state law to make a guarantee contract issued incident to that relationship valid and enforceable. A guarantee contract is issued "incident to that relationship" if it arises from and depends on existing economic transactions between the guarantor and the owner or operator.

  • Business concern means any corporation, company, limited liability company, partnership, joint venture, trust, unincorporated association or any other form of association.