Examples of Vehicle group in a sentence
For the ITT culture positive subset, more patients in the Finafloxacin group had clinical cure compared to the Vehicle group (71.1% [170/239], 46.5% [112/241] respectively); the treatment difference was 24.7% with a 95% CI of (16.1%, 33.2%).
For the ITT culture positive subset, the median time to cessation of ear pain in the Finafloxacin group and Vehicle group was 4.0 days and 5.0 days respectively; the treatment difference was -1.0 with a 95% CI of (-2.0, 0.0).
Clinical Cure at TOC Visit – Primary Efficacy Endpoint In Study C-10-018, at the TOC visit, for the ITT pathogen positive subset, 71.7% (104/145) of the patients in the Finafloxacin group had a clinical cure compared with 33.3% (46/138) of the patients in the Vehicle group; the treatment difference (38.4%) was statistically significant 4(p<0.001) with a 95% CI of (27.6%, 49.1%).
In contrast, CCI + Vehicle group had no significant change in PWT and TWL (###P < 0.001 compared with the Sham + Vehicle group).
While for the ITT culture positive subset, more patients in the Finafloxacin group had microbiological success compared to the Vehicle group (64.9% [155/239], 17.0% [41/241] respectively); the treatment difference was 47.8% with a 95%CI of (40.2%, 55.5%).
In Study C-10-019, at the TOC visit, for the ITT pathogen positive subset, 66.0% (97/147) of the patients in the Finafloxacin group had microbiological success compared with 11.5% (15/130) of the patients in the Vehicle group; the treatment difference (54.4%) was statistically significant (p<0.001) with a 95% CI of (45.0%, 63.9%).
In contrast, CCI + vehicle group had no significant change in PWT and TWL (###P < 0.001 compared with the Sham + Vehicle group) (n = 5 per group).
Microbiological Success at TOC Visit – Secondary Efficacy Endpoint #1 In Study C-10-018, at the TOC visit, for the ITT pathogen positive subset, 66.9% (97/145) of the patients in the Finafloxacin group had microbiological success compared with 13.0% (18/138) of the patients in the Vehicle group; the treatment difference (53.9%) was statistically significant (p<0.001) with a 95% CI of (44.4%, 63.4%).
While for the ITT culture positive subset, more patients in the Finafloxacin group had microbiological success compared to the Vehicle group (60.8% [189/311], 16.6% [50/302] respectively); the treatment difference was 44.2% with a 95%CI of (37.4%, 51.1%).
Time to cessation of ear pain – Secondary Efficacy Endpoint #2 In Study C-10-018, for the ITT pathogen positive subset, the median time to cessation of ear pain in the Finafloxacin group and Vehicle group was 4.0 days and 7.0 days respectively; the treatment difference was -3.0 (p<0.0001) with a 95% CI of (-5.0, -0.8).