Aventis Manufacturing and Supply Obligations Sample Clauses

Aventis Manufacturing and Supply Obligations. Aventis shall use Commercially Reasonable Efforts to provide an adequate and timely supply of Commercial Supply Requirements and, except as set forth in Section 8.2, Clinical Supply Requirements of VEGF Products in the Territory for the Collaboration. Aventis shall supply Clinical Supply Requirements and Commercial Supply Requirements for the Collaboration at Aventis’ Manufacturing Cost for each VEGF Product. Aventis may satisfy its requirements under this Section 8.3 through one of its existing manufacturing facilities, by, at its own expense, constructing and obtaining all required approvals and validations by Regulatory Authorities for, a new manufacturing facility, or, with Regeneron’s prior consent (and consistent with the Collaboration Purpose), either (i) by paying for the expansion and scale-up of Regeneron’s Existing Facility as contemplated by the Manufacturing Plan or (ii) through a Third Party manufacturer; provided that, in each case, such activities are consistent with the Manufacturing Plan prepared by the Supply Chain Sub-Committee (with input from the JDC) and approved by the JSC pursuant to Section 8.7. All costs and expenses (including capital expenditures) required to provide additional manufacturing capacity (including, if applicable, at the Existing Facility), including without limitation the related start-up and validation activities contemplated by the Manufacturing Plan, shall be paid by Aventis, it being understood and agreed that upon its purchase thereof as contemplated by the Manufacturing Plan, [*****************].