Cannabis and other drugs use Sample Clauses

Cannabis and other drugs use. Substance misuse is often highly reported among individuals experiencing their first episode psychosis compared to general population, and it is well known that psychostimulants such as amphetamines and methamphetamine can induce psychosis after repeated use (Xxxxxxxxxx et al., 2010; Xxxx et al., 2015). Important evidence comes from the association between cannabis use and increased risk for psychosis. In a meta-analysis, Xxxxxxx (Xxxxxxx, Di Forti, Xxxxx, Xxxxxx, & Xxxxxx, 2016) showed a dose–response relationship between magnitude of cannabis consumption and risk of psychosis. Individuals who used cannabis early in adolescence, frequently, and smoked mostly potent type cannabis with % of tetrahydrocannabinol (THC)=>10%, are at greatest risk. Moreover, Di Forti (Di Forti et al., 2019) investigated the role of cannabis in the variation of incidence rates reported in the multi-site EU-GEI study (Xxxxxxx et al., 2018), finding that if high-potency cannabis was no longer available, around 12% of the total first-episode psychosis cases could be prevented, increasing to 30% in London and 50% in Amsterdam. Indeed, they showed that the difference in prevalence of daily cannabis use and separately in the prevalence of use of high potency type among the population controls contributed to explain the variation in Incidence rates for Psychotic disorder across the 11 European cites.
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Related to Cannabis and other drugs use

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