Central CT Sample Clauses

Central CT imaging analysis (P2-U. Turku, P4-LUMC) (months 7  36) Participating centres will send the original axial data sets to Central Digital Bank at CNR that will forward them to the leader of WP2 at Leiden (P4-LUMC). At Leiden, the data sets will then be further analysed and reconstructed. For this purpose, a dedicated researcher- with several years of experience in performing and reading CT angiography - will view the axial data sets and select the appropriate phases for the different coronary arteries. Subsequently, curved multiplanar reformat in different angulations will be obtained for all coronary arteries and side-branches. Coronary calcium scoring will be performed by an experienced observer with the application of dedicated software. Agatston and Volume calcium scores will be obtained per coronary artery and per patient. The processed data for the CT angiography studies will be read by a cardiologist together with a dedicated researcher. A maximum of 250 scans will be re-evaluated to assess inter- and intra- observer variability (together with P2-U. Turku). A Local Database for entering the CT angiography data will be constructed, continuously updated and interfaced with Central Database. Data will be checked by the WP2 leader for consistency throughout the project.
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