Coronary vasodilators Sample Clauses

Coronary vasodilators. Nitrates are known to be effective coronary vasodilators, although their effect is limited by the side effects of nitrate-induced flushing, hypotension and syncope, as well as the reported nitrate tolerance. Moreover, intact epicardial coronary arteries dilate promptly after the administration of nitrates or other kinds of vasodilators27, while in contrast, it remains controversial28-30as to whether the coronary atherosclerotic site responds to vasodilator agents; this continues to be an important topic in terms of the treatment of stable angina pectoris. Therefore, other vasodilators than nitrates should be used to more accurately assess the vasodilator potential at atherosclerotic lesions.
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