Fractures in osteoporosis Sample Clauses

Fractures in osteoporosis. The significant clinical outcome in OP is the increased likelihood of fracture. Fragility fractures at the spine, hip and forearm are the most typical sites, although fractures of the ribs, humerus and pelvis are not uncommon. The annual incidence of osteoporotic fractures (including recurrent ones) is 180,000 in England and Wales [151]. The combined lifetime risk for hip, forearm and vertebral fractures coming to clinical attention is around 40%, equivalent to the risk for CV disease [152]. Fractures result in severe pain and disability and the cost of osteoporotic fractures to the National Health Service (NHS) each year is over £1.8 billion [153] and with an ageing population, it is estimated that the number of osteoporotic fractures over the next 50 years will double in Europe [154]. There is considerable morbidity after hip fracture, with 25-50% of patients becoming more dependent and many needing residential or nursing care [155]. Mortality rates are approximately 10-20% after hip fracture; with an estimated 14,000 people dying each year in the UK following an osteoporotic hip fracture [156].
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