Outline of Subsequent Chapters Sample Clauses

Outline of Subsequent Chapters. Structure based drug design is an integral part of most industrial drug discovery program and it is the major subject of research for many academic laboratories. The fundamental assumption of structure based drug design is introduced and its rationality is investigated by a crystal structure database survey in Chapter 2. Chapter 3 and 4 describe the applications of the structure based drug design in two specific cases, the liver receptor homolog-1 (LRH-1) antagonist design and truncated taxane design for stabilizing microtubule. In Chapter 5, a case based on homology modeling is introduced, and in Chapter 6, a quantum calculation related project is described.
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Outline of Subsequent Chapters. In Chapter 2 and Chapter 4, docking and scoring are performed on PTX binding to human and mouse MD-2,[7] and also worked on LPS binding to human TLR4/MD-2 dimer with or without KDO moiety. The docking results explained bio-activity differences based on the experiment results. In Chapter 3, protein-protein docking methodology, Xxxxxxx, was adopted to find the TLR4/MD-2 dimerization model. In Chapter 5, a quantum calculation related project is described. Chapter 6 and 7 describe the applications of the structure based drug design in two specific cases, histone lysine methyltransferase (H3K9me2) inhibitor design [8, 9] and Chemokine Receptor Type 4 (CXCR4) inhibitors design. Chapter 2 Paclitaxel binding to Human and Mouse MD-2

Related to Outline of Subsequent Chapters

  • Adoption of Subsequent Orders to Incorporate Terms That a State Mortgage Regulator, if deemed necessary under the laws and regulations of the corresponding Participating State, may issue a separate administrative order to adopt and incorporate the terms and conditions of this Agreement. A State Mortgage Regulator may sua sponte issue such subsequent order without the review and approval of Respondent provided the subsequent order does not amend, alter, or otherwise change the terms of the Agreement. In the event a subsequent order amends, alters, or otherwise changes the terms of the Agreement, the terms of the Agreement, as set forth herein, will control.

  • Agreement Changes The Company reserves the right to change the terms of this Agreement and the Plan without your consent to the extent necessary or desirable to comply with the requirements of Code section 409A, the Treasury regulations and other guidance thereunder.

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  • Review of Submittals A/E and ODR review is only for conformance with the design concept and the information provided in the Contract Documents. Responses to submittals will be in writing. The approval of a separate item does not indicate approval of an assembly in which the item functions. The approval of a submittal does not relieve the Contractor of responsibility for any deviation from the requirements of the Contract unless the Contractor informs the A/E and ODR of such deviation in a clear, conspicuous, and written manner on the submittal transmittal and at the time of submission, and obtains the A/E’s and Owner’s written specific approval of the particular deviation.

  • TYPES OF CONTRACT MODIFICATIONS In order to expedite processing of a contract modification, where proposed changes involve more than one category below, each change should be submitted to OGS as a separate request.

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