Common use of Position Duties and Location Clause in Contracts

Position Duties and Location. Executive shall serve as President and Chief Medical Officer reporting to the Company’s Chief Executive Officer (“CEO”). Executive shall perform those duties and responsibilities as are customary for such position and as may be directed by the Company and the Board from time to time. Executive is expected to attend and participate in Board of Director or any appropriate Board Committee meetings unless CEO determines otherwise. During Executive’s employment with the Company, Executive shall devote Executive’s best efforts and substantially all of Executive’s business time and attention to the business of the Company, except for approved vacation periods and reasonable periods of illness or other incapacities permitted by the Company’s general employment policies. Executive’s primary office location will be the Company’s offices in New York, New York. Notwithstanding the foregoing, the Company reserves the right to reasonably require Executive to perform Executive’s duties at places other than Executive’s primary office location from time to time, and to require reasonable business travel. During Executive’s employment with the Company, Executive shall not engage in any activity that conflicts with or is detrimental to the Company’s best interests, as determined by the CEO. Executive may participate in side activities such as board or committee member, advisor or consultant (the “Activities”), provided that Executive obtains the CEO’s prior written consent and that none of the following activities involve activities in the area of neurology, detract from Ovid’s reputation, impact Executive’s full time duties to the Company, or could reasonably result in the disclosure or use of the Company’s proprietary or confidential information. The CEO may rescind the consent to Executive’s participation in the Activities, or participation in other business or public activities, if the CEO, in the CEO’s sole discretion, determines that such activities compromise or threaten to compromise the Company’s business interests or conflict with Executive’s duties to the Company.

Position Duties and Location. Executive shall continue to serve as President and Chief Medical Officer Senior Vice President, Global Regulatory Affairs, reporting to the Company’s Chief Executive Officer (“CEO”). Executive shall perform those duties and responsibilities as are customary for such position and as may be directed by the Company and the Board from time to time. Executive is expected to attend and participate in Board of Director or any appropriate Board Committee meetings unless CEO determines otherwise. During Executive’s employment with the Company, Executive shall devote Executive’s best efforts and substantially all of Executive’s business time and attention to the business of the Company, except for approved vacation periods and reasonable periods of illness or other incapacities permitted by the Company’s general employment policies. Executive’s primary office location will be the Company’s offices in New York, New York. Notwithstanding the foregoing, the Company reserves the right to reasonably require Executive to perform Executive’s duties at places other than Executive’s primary office location from time to time, and to require reasonable business travel. During Executive’s employment with the Company, Executive shall not engage in any activity that conflicts with or is detrimental to the Company’s best interests, as determined by the CEO. Executive may participate in side activities such as board or committee member, advisor or consultant (the “Activities”), provided Provided that Executive obtains the CEO’s prior written consent for each of the following activities, which consent shall not be unreasonably withheld, and that none of the following activities involve activities in the area of neurology, detract from Ovid’s reputation, impact Executive’s full time duties to the Company, or could reasonably result in the disclosure or use of the Company’s proprietary or confidential information, Executive may serve as a board or committee member, advisor or consultant (the “Activities”). The CEO may rescind the CEO’s consent to Executive’s participation in the Activities, or participation in other business or public activities, if the CEO, in the CEO’s sole discretion, determines that such activities compromise or threaten to compromise the Company’s business interests or conflict with Executive’s duties to the Company.

Position Duties and Location. Executive shall continue to serve as President and Chief Medical Officer CSO, reporting to the Company’s Chief Executive Officer (“CEO”). Executive shall perform those duties and responsibilities as are customary for such position positions and as may be directed by the Company and the Board from time to time. Executive is expected , including: (1) establishing and maintaining the Company’s strategic clinical and regulatory development roadmap in order to attend support the overall corporate strategy set by the Board; (2) maintaining the highest quality of scientific foundations of the Company’s development process; (3) providing members of the Company’s executive team with scientific input in the areas of business development, clinical development and participate commercialization, financial planning and execution, regulatory matters, manufacturing, funding processes and initiatives; (4) providing strategic input from a scientific standpoint for the Company’s mid- and long-term goals; (5) recommending membership of, managing and insuring effective output from the Company’s Scientific Advisory Board; (6) expansion and management of intellectual property related to medicines in Board of Director the Company’s pipeline; (7) hiring, managing and retaining key scientific staff; and (8) where appropriate, participating and representing the Company at scientific conferences or any appropriate Board Committee meetings unless CEO determines otherwisepublic venues as requested by the Company. During Executive’s employment with the Company, Executive shall devote Executive’s best efforts and substantially all of Executive’s business time and attention to the business of the Company, except for approved vacation periods and reasonable periods of illness or other incapacities permitted by the Company’s general employment policies. Executive’s primary office location will be the Company’s offices in New York, New York. Notwithstanding the foregoing, the Company reserves the right to reasonably require Executive to perform Executive’s duties at places other than Executive’s primary office location from time to time, and to require reasonable business travel. During Executive’s employment with the Company, Executive shall not engage in any activity that conflicts with or is detrimental to the Company’s best interests, as determined by the CEO. Executive may participate in side activities such as board or committee member, advisor or consultant (the “Activities”), provided that Executive obtains the CEO’s prior written consent and that none of the following activities involve activities in the area of neurology, detract from Ovid’s reputation, impact Executive’s full time duties to the Company, or could reasonably result in the disclosure or use of the Company’s proprietary or confidential information. The CEO may rescind the consent to Executive’s participation in the Activities, or participation in other business or public activities, if the CEO, in the CEO’s sole discretion, determines that such activities compromise or threaten to compromise the Company’s business interests or conflict with Executive’s duties to the Company.143429480 v3

Position Duties and Location. Executive shall continue to serve as President CEO and Chief Medical Officer Chairman of the Board, reporting to the Company’s Chief Executive Officer (“CEO”)Board. Executive shall perform those duties and responsibilities as are customary for such position positions and as may be directed by the Company and the Board from time to time. Executive As CEO, Executive’s duties shall include responsibility for: (a) all day-to-day management decisions and for leading the development and execution of the Company’s short and long-term strategy, and (b) communicating on behalf of the Company to stockholders, employees, government authorities and the public. Executive’s specific responsibilities as CEO include, but are not limited to: (i) setting the strategy for the Company and ensuring the organization is expected appropriately staffed and has appropriate financial, physical and human resources to attend execute the strategy; (ii) assessing and participate monitoring significant business risks and trends; (iii) ensuring that effective internal controls and systems are in place in order for the Company to conduct its activities lawfully and ethically; and (iv) ensuring that the Board is properly informed and ensuring the integrity of Director or any appropriate all public disclosures. As Chairman of the Board, Executive’s duties include presiding at all meetings of the Board Committee meetings unless CEO determines otherwiseand stockholders and developing the agenda for each Board meeting and circulating it in advance of the meeting. During Executive’s employment with the Company, Executive shall devote Executive’s best efforts and substantially all of Executive’s business time and attention to the business of the Company, except for approved vacation periods and reasonable periods of illness or other incapacities permitted by the Company’s general employment policies. Executive’s primary office location will be the Company’s offices in New York, New York. Notwithstanding the foregoing, the Company reserves the right to reasonably require Executive to perform Executive’s duties at places other than Executive’s primary office location from time to time, and to require reasonable business travel. During Executive’s employment with the Company, Executive shall not engage in any activity that conflicts with or is detrimental to the Company’s best interests, as determined by the CEO. Executive may participate in side activities such as board or committee member, advisor or consultant (the “Activities”), provided that Executive obtains the CEO’s prior written consent and that none of the following activities involve activities in the area of neurology, detract from Ovid’s reputation, impact Executive’s full time duties to the Company, or could reasonably result in the disclosure or use of the Company’s proprietary or confidential information. The CEO may rescind the consent to Executive’s participation in the Activities, or participation in other business or public activities, if the CEO, in the CEO’s sole discretion, determines that such activities compromise or threaten to compromise the Company’s business interests or conflict with Executive’s duties to the CompanyBoard.

Position Duties and Location. Executive shall serve as President and Chief Medical Officer Executive Vice President, Finance, Corporate Controller & Treasurer reporting to the Company’s Chief Executive Officer (“CEO”). Executive shall perform those duties and responsibilities as are customary for such position and as may be directed by the Company and the Board from time to time. Executive is expected to attend and participate in Board of Director or any appropriate Board Committee meetings unless CEO determines otherwise. During Executive’s employment with the Company, Executive shall devote Executive’s best efforts and substantially all of Executive’s business time and attention to the business of the Company, except for approved vacation periods and reasonable periods of illness or other incapacities permitted by the Company’s general employment policies. Executive’s primary office location will be the Company’s offices in New York, New York. Notwithstanding the foregoing, the Company reserves the right to reasonably require Executive to perform Executive’s duties at places other than Executive’s primary office location from time to time, and to require reasonable business travel. During Executive’s employment with the Company, Executive shall not engage in any activity that conflicts with or is detrimental to the Company’s best interests, as determined by the CEO. Executive may participate in side activities such as board or committee member, advisor or consultant (the “Activities”), provided that Executive obtains the CEO’s prior written consent consent, and that none of the following activities involve activities in the area of neurology, detract from Ovid’s reputation, impact Executive’s full time duties to the Company, or could reasonably result in the disclosure or use of the Company’s proprietary or confidential information. The CEO may rescind the consent to Executive’s participation in the Activities, or participation in other business or public activities, if the CEO, in the CEO’s sole discretion, determines that such activities compromise or threaten to compromise the Company’s business interests or conflict with Executive’s duties to the Company.. EXHIBIT 10.16