Common use of Schedule of Changes Clause in Contracts

Schedule of Changes. Sponsor and Omnicare CR agree to the following additional work and reduced services pursuant to the general terms and conditions set forth in the Agreement: **** Certain confidential information contained in this document, marked with four asterisks, has been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule 24b-2 of the Securities Exchange Act of 1934, as amended. Reference Services to be Billed Estimated Additional Service Fee (AUS$) Pursuant to Exhibit A, Omnicare CR will provide additional biometrics support for the Sponsor’s Cohort Study of PEP005 Topical Gel, Protocol # PEP005-004, Version 3 Unique Tables: * Estimated number of unique tables in original budget = **** $ **** * Actual number of unique tables = **** * Variance = **** unique tables @ AUS$**** Unique Listings: $ **** * Estimated number of unique listings in original budget = **** * Actual number of unique listings = **** * Variance = **** unique listings @ AUS$**** Reference Services to be Billed Estimated Reduced Service Fee (AUS$) Pursuant to Exhibit A, Omnicare CR will provide additional biometrics support for the Sponsor’s Cohort Study of PEP005 Topical Gel, Protocol # PEP005-004, Version 3 Repeat Tables: * Estimated number of repeat tables in original budget = **** $ **** * Actual number of repeat tables = **** * Variance = **** repeat tables @ AUS$**** Repeat Listings: $ **** * Estimated number of repeat listings in original budget = **** * Actual number of repeat listings = **** * Variance = **** repeat listings @ AUS$**** Total Estimated Service Fees to be Billed **** * Total Estimated Service Fees Not to be Billed **** Total Estimated Pass Through Expenses **** ** * The Estimated Service Fees set forth above represent the original unit costs set forth in the Agreement and are subject to any annual price increase(s) applied against the original unit costs. ** Sponsor will be billed for actual Pass-Through Expenses incurred in support of the Project. **** Certain confidential information contained in this document, marked with four asterisks, has been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule 24b-2 of the Securities Exchange Act of 1934, as amended.

Schedule of Changes. Sponsor and Omnicare Ominicare CR agree to the following changes and additional work and reduced services pursuant to the general terms and conditions set forth in the Agreement: [REMAINDER OF PAGE INTENTIONALLY LEFT BLANK] **** Certain confidential information contained in this document, marked with four asterisks, has been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule 24b-2 of the Securities Exchange Act of 1934, as amended. Reference Services to be Billed Changes and/or Additions Estimated Additional Service Fee (AUS$) Pursuant to Exhibit AC, Omnicare CR will provide additional biometrics clinical data management support for the Sponsor’s Cohort Study of PEP005 Topical Gel, Protocol # PEP005PEPO05-004, Version 3 Unique Tables: * Estimated number O03 Revised costing for tables and listings presented in Statistical Analysis Plan. The original proposal had an estimate of unique tables in original budget = Tables (**** $ unique/ **** repeat), Listings (**** unique/ **** repeat) and Figures (**** unique/ **** repeat). Following on from design of data displays and reporting requirements there has been an increase in the number of Tables and Listings presented in the Statistical Analysis Plan. The updated count of Tables is **** unique/ **** repeat, Listings is **** unique/ **** repeat and **** unique/ **** repeat Figure. Service Fees to be Invoiced **** * Actual number of unique tables = **** * Variance = **** unique tables @ AUS$$**** Unique Listings: */table = $ **** * Estimated number of unique listings in original budget **** repeat table @ $****/table = $**** * Actual number of unique listings = **** * Variance = **** unique listings @ AUS$$**** Reference Services to be Billed Estimated Reduced Service Fee (AUS$) Pursuant to Exhibit A, Omnicare CR will provide additional biometrics support for the Sponsor’s Cohort Study of PEP005 Topical Gel, Protocol # PEP005-004, Version 3 Repeat Tables: * Estimated number of repeat tables in original budget */listing = **** $ $**** * Actual number of repeat tables = **** * Variance = **** repeat tables @ AUS$**** Repeat Listings: $ **** * Estimated number of repeat listings in original budget = **** * Actual number of repeat listings = **** * Variance = **** repeat listings @ AUS$$****/listing = $**** Total Estimated Service Fees not to be Billed Invoiced **** * Total Estimated Service Fees Not to be Billed **** Total Estimated Pass Through Expenses unique figure @ $****/figure = ($ ****) * **** repeat figure @ $** ***/figure = ($****) Actuals will be billed. * The Estimated Service Fees set forth above represent the original unit costs set forth in the Agreement and are subject to any annual price increase(s) applied against the original unit costs. ** Sponsor will be billed for actual Pass-Through Expenses incurred in support of the Project. **** Certain confidential information contained in this document, marked with four asterisks, has been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule 24b-2 of the Securities Exchange Act of 1934, as amended.

Schedule of Changes. Sponsor and Omnicare CR agree to the following additional work and reduced services pursuant to the general terms and conditions set forth in the Agreement: **** Certain confidential information contained in this document, marked with four asterisks, has been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule 24b-2 of the Securities Exchange Act of 1934, as amended. Reference Services to be Billed Estimated Additional Service Fee (AUS$) Pursuant to Exhibit AB, Omnicare CR will provide additional biometrics support for the Sponsor’s Cohort Study of PEP005 Topical Gel, Protocol # PEP005#PEP0O5-004001, Version 3 2 Unique Tables: * Estimated number of unique tables in original budget = **** $ **** * Actual number of unique tables = **** * Variance = **** unique tables @ AUS$**** **** Repeat Tables: **** * Estimated number of repeat tables in original budget = **** * Actual number of repeat tables = **** * Variance = **** repeat table @ AUS$**** Unique Listings: $ **** * Estimated number of unique listings in original budget = **** * Actual number of unique listings = **** * Variance = **** unique listings @ AUS$**** Reference Services to be Billed Estimated Reduced Service Fee (AUS$) Pursuant to Exhibit A, Omnicare CR will provide additional biometrics support for the Sponsor’s Cohort Study of PEP005 Topical Gel, Protocol # PEP005-004, Version 3 Repeat Tables: * Estimated number of repeat tables in original budget = **** $ **** * Actual number of repeat tables = **** * Variance = **** repeat tables @ AUS$**** Repeat Listings: $ **** * Estimated number of repeat listings in original budget = **** * Actual number of repeat listings = **** * Variance = **** repeat listings @ AUS$**** Reference Services Not to be Billed Estimated Reduced Service Fee (AUS$) Pursuant to Exhibit B, Omnicare CR will provide biometrics support for the Sponsor’s Cohort Study of PEP005 Topical Gel, Protocol # PEP005-001, Version 2 Unique Figures: * Estimated number of unique figures in original budget = **** * Actual number of unique figures = **** * variance = **** unique figure @ AUS$**** **** Repeat Figures: **** * Estimated number of repeat figures in original budget = **** * Actual number of repeat figures = **** * Variance = **** repeat figure @ AUS$**** Total Estimated Service Fees to be Billed **** * Total Estimated Service Fees Not to be Billed **** Total Estimated Pass Through Expenses **** ** **** Certain confidential information contained in this document, marked with four asterisks, has been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule 24b-2 of the Securities Exchange Act of 1934, as amended. * The Estimated Service Fees set forth above represent the original unit costs set forth in the Agreement and are subject to any annual price increase(s) applied against the original unit costs. ** Sponsor will be billed for actual Pass-Through Expenses incurred in support of the Project. **** Certain confidential information contained in this document, marked with four asterisks, has been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule 24b-2 of the Securities Exchange Act of 1934, as amended.

Schedule of Changes. Sponsor and Omnicare CR agree to the following additional work and reduced services pursuant to the general terms and conditions set forth in the Agreement: **** Certain confidential information contained in this document, marked with four asterisks, has been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule 24b-2 406 of the Securities Exchange Act of 19341933, as amended. Reference Services to be Billed Estimated Additional Service Fee (AUS$) Pursuant to Exhibit A, Omnicare CR will provide additional biometrics support for the Sponsor’s Cohort Study of PEP005 Topical Gel, Protocol # PEP005-004, Version 3 Unique Tables: * Estimated number of unique tables in original budget = **** $ **** * Actual number of unique tables = **** * Variance = **** unique tables @ AUS$**** Unique Listings: $ **** * Estimated number of unique listings in original budget = **** * Actual number of unique listings = **** * Variance = **** unique listings @ AUS$**** Reference Services to be Billed Estimated Reduced Service Fee (AUS$) Pursuant to Exhibit A, Omnicare CR will provide additional biometrics support for the Sponsor’s Cohort Study of PEP005 Topical Gel, Protocol # PEP005-004, Version 3 Repeat Tables: * Estimated number of repeat tables in original budget = **** $ **** * Actual number of repeat tables = **** * Variance = **** repeat tables @ AUS$**** Repeat Listings: $ **** * Estimated number of repeat listings in original budget = **** * Actual number of repeat listings = **** * Variance = **** repeat listings @ AUS$**** Total Estimated Service Fees to be Billed **** * Total Estimated Service Fees Not to be Billed **** Total Estimated Pass Through Expenses **** ** * The Estimated Service Fees set forth above represent the original unit costs set forth in the Agreement and are subject to any annual price increase(s) applied against the original unit costs. ** Sponsor will be billed for actual Pass-Through Expenses incurred in support of the Project. **** Certain confidential information contained in this document, marked with four asterisks, has been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule 24b-2 406 of the Securities Exchange Act of 19341933, as amended.

Schedule of Changes. Sponsor and Omnicare CR agree to the following additional work and reduced services pursuant to the general terms and conditions set forth in the Agreement: **** Certain confidential information contained in this document, marked with four asterisks, has been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule 24b-2 406 of the Securities Exchange Act of 19341933, as amended. Estimated Additional Reference Services to be Billed Estimated Additional Service Fee (AUS$) Pursuant to Exhibit A, Omnicare CR will provide additional biometrics support for the Sponsor’s Cohort Study of PEP005 Topical Gel, Protocol # PEP005-004, Version 3 Unique Tables: * Estimated number of unique tables in original budget = **** $ **** * Actual number of unique tables = **** $ **** * Variance = **** unique tables @ AUS$**** Unique Listings: $ **** * Estimated number of unique listings in original budget = **** * Actual number of unique listings = **** * Variance = **** unique listings @ AUS$**** Estimated Reduced Reference Services to be Billed Estimated Reduced Service Fee (AUS$) Pursuant to Exhibit A, Omnicare CR will provide additional biometrics support for the Sponsor’s Cohort Study of PEP005 Topical Gel, Protocol # PEP005-004, Version 3 Repeat Tables: * Estimated number of repeat tables in original budget = **** $ **** * Actual number of repeat tables = **** $ **** * Variance = **** repeat tables @ AUS$**** Repeat Listings: $ **** * Estimated number of repeat listings in original budget = **** * Actual number of repeat listings = **** * Variance = **** repeat listings @ AUS$**** Total Estimated Service Fees to be Billed **** * Total Estimated Service Fees Not to be Billed **** Total Estimated Pass Through Expenses **** ** * The Estimated Service Fees set forth above represent the original unit costs set forth in the Agreement and are subject to any annual price increase(s) applied against the original unit costs. ** Sponsor will be billed for actual Pass-Through Expenses incurred in support of the Project. **** Certain confidential information contained in this document, marked with four asterisks, has been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule 24b-2 406 of the Securities Exchange Act of 19341933, as amended.

Schedule of Changes. Sponsor and Omnicare Ominicare CR agree to the following changes and additional work and reduced services pursuant to the general terms and conditions set forth in the Agreement: [REMAINDER OF PAGE INTENTIONALLY LEFT BLANK] **** Certain confidential information contained in this document, marked with four asterisks, has been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule 24b-2 406 of the Securities Exchange Act of 19341933, as amended. Reference Services to be Billed Changes and/or Additions Estimated Additional Service Fee (AUS$) Pursuant to Exhibit AC, Omnicare CR will provide additional biometrics clinical data management support for the Sponsor’s Cohort Study of PEP005 Topical Gel, Protocol # PEP005PEPO05-004, Version 3 Unique Tables: * Estimated number O03 Revised costing for tables and listings presented in Statistical Analysis Plan. The original proposal had an estimate of unique tables in original budget = Tables (**** $ unique/ **** repeat), Listings (**** unique/ **** repeat) and Figures (**** unique/ **** repeat). Following on from design of data displays and reporting requirements there has been an increase in the number of Tables and Listings presented in the Statistical Analysis Plan. The updated count of Tables is **** unique/ **** repeat, Listings is **** unique/ **** repeat and **** unique/ **** repeat Figure. Service Fees to be Invoiced **** * Actual number of unique tables = **** * Variance = **** unique tables @ AUS$$**** Unique Listings: */table = $ **** * Estimated number of unique listings in original budget **** repeat table @ $****/table = $**** * Actual number of unique listings = **** * Variance = **** unique listings @ AUS$$**** Reference Services to be Billed Estimated Reduced Service Fee (AUS$) Pursuant to Exhibit A, Omnicare CR will provide additional biometrics support for the Sponsor’s Cohort Study of PEP005 Topical Gel, Protocol # PEP005-004, Version 3 Repeat Tables: * Estimated number of repeat tables in original budget */listing = **** $ $**** * Actual number of repeat tables = **** * Variance = **** repeat tables @ AUS$**** Repeat Listings: $ **** * Estimated number of repeat listings in original budget = **** * Actual number of repeat listings = **** * Variance = **** repeat listings @ AUS$$****/listing = $**** Total Estimated Service Fees not to be Billed Invoiced **** * Total Estimated Service Fees Not to be Billed **** Total Estimated Pass Through Expenses unique figure @ $****/figure = ($ ****) * **** repeat figure @ $** ***/figure = ($****) Actuals will be billed. * The Estimated Service Fees set forth above represent the original unit costs set forth in the Agreement and are subject to any annual price increase(s) applied against the original unit costs. ** Sponsor will be billed for actual Pass-Through Expenses incurred in support of the Project. **** Certain confidential information contained in this document, marked with four asterisks, has been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule 24b-2 406 of the Securities Exchange Act of 19341933, as amended.

Schedule of Changes. Sponsor and Omnicare Ominicare CR agree to the following changes and additional work and reduced services pursuant to the general terms and conditions set forth in the Agreement: [REMAINDER OF PAGE INTENTIONALLY LEFT BLANK] **** Certain confidential information contained in this document, marked with four asterisks, has been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule 24b-2 406 of the Securities Exchange Act of 19341933, as amended. Reference Services to be Billed Changes and/or Additions Estimated Additional Service Fee (AUS$) Pursuant to Exhibit AC, Omnicare CR will provide additional biometrics clinical data management support for the Sponsor’s Cohort Study of PEP005 Topical Gel, Protocol # PEP005PEPO05-004, Version 3 Unique Tables: * Estimated number O03 Revised costing for tables and listings presented in Statistical Analysis Plan. The original proposal had an estimate of unique tables in original budget = Tables (**** $ unique/ **** repeat), Listings (**** unique/ **** repeat) and Figures (**** unique/ **** repeat). Following on from design of data displays and reporting requirements there has been an increase in the number of Tables and Listings presented in the Statistical Analysis Plan. The updated count of Tables is **** unique/ **** repeat, Listings is **** unique/ **** repeat and **** unique/ **** repeat Figure. Service Fees to be Invoiced **** * Actual number of unique tables = **** * Variance = **** unique tables @ AUS$$**** Unique Listings: $ */table = $**** * Estimated number of unique listings in original budget **** repeat table @ $****/table = $**** * Actual number of unique listings = **** * Variance = **** unique listings @ AUS$$**** Reference Services to be Billed Estimated Reduced Service Fee (AUS$) Pursuant to Exhibit A, Omnicare CR will provide additional biometrics support for the Sponsor’s Cohort Study of PEP005 Topical Gel, Protocol # PEP005-004, Version 3 Repeat Tables: * Estimated number of repeat tables in original budget */listing = **** $ $**** * Actual number of repeat tables = **** * Variance = **** repeat tables @ AUS$**** Repeat Listings: $ **** * Estimated number of repeat listings in original budget = **** * Actual number of repeat listings = **** * Variance = **** repeat listings @ AUS$$****/listing = $**** Total Estimated Service Fees not to be Billed Invoiced **** * Total Estimated Service Fees Not to be Billed **** Total Estimated Pass Through Expenses unique figure @ $****/figure = ($ ****) * **** repeat figure @ $** ***/figure = ($****) Actuals will be billed. * The Estimated Service Fees set forth above represent the original unit costs set forth in the Agreement and are subject to any annual price increase(s) applied against the original unit costs. ** Sponsor will be billed for actual Pass-Through Expenses incurred in support of the Project. **** Certain confidential information contained in this document, marked with four asterisks, has been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule 24b-2 406 of the Securities Exchange Act of 19341933, as amended.

Schedule of Changes. Sponsor and Omnicare CR agree to the following additional work and reduced services pursuant to the general terms and conditions set forth in the Agreement: **** Certain confidential information contained in this document, marked with four asterisks, has been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule 24b-2 406 of the Securities Exchange Act of 19341933, as amended. Estimated Additional Reference Services to be Billed Estimated Additional Service Fee (AUS$) Pursuant to Exhibit AB, Omnicare CR will provide additional biometrics support for the Sponsor’s Cohort Study of PEP005 Topical Gel, Protocol # PEP005#PEP0O5-004001, Version 3 2 Unique Tables: * Estimated number of unique tables in original budget = **** $ **** * Actual number of unique tables = **** * Variance = **** unique tables @ AUS$**** Repeat Tables: **** * Estimated number of repeat tables in original budget = **** * Actual number of repeat tables = **** * Variance = **** repeat table @ AUS$**** Unique Listings: $ **** * Estimated number of unique listings in original budget = **** * Actual number of unique listings = **** * Variance = **** unique listings @ AUS$**** Reference Services to be Billed Estimated Reduced Service Fee (AUS$) Pursuant to Exhibit A, Omnicare CR will provide additional biometrics support for the Sponsor’s Cohort Study of PEP005 Topical Gel, Protocol # PEP005-004, Version 3 Repeat Tables: * Estimated number of repeat tables in original budget = **** $ **** * Actual number of repeat tables = **** * Variance = **** repeat tables @ AUS$**** Repeat Listings: $ **** * Estimated number of repeat listings in original budget = **** * Actual number of repeat listings = **** * Variance = **** repeat listings @ AUS$**** Estimated Reduced Reference Services Not to be Billed Service Fee (AUS$) Pursuant to Exhibit B, Omnicare CR will provide biometrics support for the Sponsor’s Cohort Study of PEP005 Topical Gel, Protocol # PEP005-001, Version 2 Unique Figures: * Estimated number of unique figures in original budget = **** * Actual number of unique figures = **** * variance = **** unique figure @ AUS$**** **** Repeat Figures: **** * Estimated number of repeat figures in original budget = **** * Actual number of repeat figures = **** * Variance = **** repeat figure @ AUS$**** Total Estimated Service Fees to be Billed **** * Total Estimated Service Fees Not to be Billed **** Total Estimated Pass Through Expenses **** ** **** Certain confidential information contained in this document, marked with four asterisks, has been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule 406 of the Securities Act of 1933, as amended. * The Estimated Service Fees set forth above represent the original unit costs set forth in the Agreement and are subject to any annual price increase(s) applied against the original unit costs. ** Sponsor will be billed for actual Pass-Through Expenses incurred in support of the Project. **** Certain confidential information contained in this document, marked with four asterisks, has been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule 24b-2 of the Securities Exchange Act of 1934, as amended.

Schedule of Changes. Sponsor and Omnicare CR agree to the following additional work and reduced services pursuant to the general terms and conditions set forth in the Agreement: **** Certain confidential information contained in this document, marked with four asterisks, has been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule 24b-2 406 of the Securities Exchange Act of 19341933, as amended. Reference Services to be Billed Estimated Additional Service Fee (AUS$) Pursuant to Exhibit AB, Omnicare CR will provide additional biometrics support for the Sponsor’s Cohort Study of PEP005 Topical Gel, Protocol # PEP005#PEP0O5-004001, Version 3 2 Unique Tables: * Estimated number of unique tables in original budget = **** $ **** * Actual number of unique tables = **** * Variance = **** unique tables @ AUS$**** **** Repeat Tables: **** * Estimated number of repeat tables in original budget = **** * Actual number of repeat tables = **** * Variance = **** repeat table @ AUS$**** Unique Listings: $ **** * Estimated number of unique listings in original budget = **** * Actual number of unique listings = **** * Variance = **** unique listings @ AUS$**** Reference Services to be Billed Estimated Reduced Service Fee (AUS$) Pursuant to Exhibit A, Omnicare CR will provide additional biometrics support for the Sponsor’s Cohort Study of PEP005 Topical Gel, Protocol # PEP005-004, Version 3 Repeat Tables: * Estimated number of repeat tables in original budget = **** $ **** * Actual number of repeat tables = **** * Variance = **** repeat tables @ AUS$**** Repeat Listings: $ **** * Estimated number of repeat listings in original budget = **** * Actual number of repeat listings = **** * Variance = **** repeat listings @ AUS$**** Reference Services Not to be Billed Estimated Reduced Service Fee (AUS$) Pursuant to Exhibit B, Omnicare CR will provide biometrics support for the Sponsor’s Cohort Study of PEP005 Topical Gel, Protocol # PEP005-001, Version 2 Unique Figures: * Estimated number of unique figures in original budget = **** * Actual number of unique figures = **** * variance = **** unique figure @ AUS$**** **** Repeat Figures: **** * Estimated number of repeat figures in original budget = **** * Actual number of repeat figures = **** * Variance = **** repeat figure @ AUS$**** Total Estimated Service Fees to be Billed **** * Total Estimated Service Fees Not to be Billed **** Total Estimated Pass Through Expenses **** ** **** Certain confidential information contained in this document, marked with four asterisks, has been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule 406 of the Securities Act of 1933, as amended. * The Estimated Service Fees set forth above represent the original unit costs set forth in the Agreement and are subject to any annual price increase(s) applied against the original unit costs. ** Sponsor will be billed for actual Pass-Through Expenses incurred in support of the Project. **** Certain confidential information contained in this document, marked with four asterisks, has been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule 24b-2 of the Securities Exchange Act of 1934, as amended.