Summarising gaps in the literature Sample Clauses

Summarising gaps in the literature. The research published to date suggests that both social causation (i.e., gene-environment interaction) and social selection (i.e., gene-environment correlation) processes contribute to observed associations between socioeconomic conditions and mental health outcomes (Dohrenwend et al., 1992; Xxxxxxxx et al., 2018; Xxx et al., 2020; Xxxx & Xxxx, 2018). However, significant gaps remain in our understanding. Few studies have explored the moderating effects of socioeconomic status indicators on the aetiology of mental health outcomes using a behavioural genetic approach. Even fewer have explored potential differences in the effects of individual socioeconomic indicators. Further, the use of child twin data in prior GxE studies has not allowed researchers to test for gene-environment interaction in the presence of gene- environment correlation (Xxxxxxx, 2002; van der Sluis et al., 2012). Crucially, no studies have investigated gene-environment interplay processes underpinning the relationship between socioeconomic status and mental health outcomes in lower- and middle-income populations. Finally, questions remain as to our ability to detect the true effects of socioeconomic conditions on mental health, given the potential for bias in phenotypic and genetic analyses when studying samples characterised by self-selection.