Theoretical GxE frameworks Sample Clauses

Theoretical GxE frameworks. Table 3 presents a summary of four main theoretical models that have been used to understand the nature of GxE: the diathesis stress, differential susceptibility, bioecological (social compensation), and social control/push models. In this section, I provide a brief description of each of the primary theories and relevant empirical examples from prior literature. Note that while these models are presented as distinct, it is entirely possible that more than one model may be needed to explain the pattern of GxE observed for a particular combination of moderator and phenotype. That is, these models should be regarded as useful heuristics that can be used to interpret the effects identified in GxE studies, however, findings from any one specific study may suggest the plausibility of more than one framework.
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