Tacrolimus Sample Clauses

Tacrolimus. In the last decade, tacrolimus has been used routinely in the post-transplant setting and consequently data regarding its safety in pregnancy is emerging. The neonatal malformation rate in reported series is approximately 4%, which is similar to the risk associated with cyclosporine. (179, 188, 192) In LT recipients Xxxx et al. described 49 pregnancies on tacrolimus.
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Tacrolimus. The purpose of this document is to assist the provision of DMARDs. Initiation of treatment should be the responsibility of a specialist. Once the patient is clinically stable on treatment, it is then appropriate for GP’s without a special interest to prescribe this drug over the longer term within the guidance of an ESCA. This document set out the responsibilities of the Specialist and the General Practitioner in the provision of shared care. It also outlines the DMARD monitoring guidelines.
Tacrolimus. Adults and adolescents (16 years of age and above) Treatment of moderate to severe atopic dermatitis in adults who are not adequately responsive to or are intolerant of conventional therapies such as topical corticosteroids. Children (2 years of age and above) Treatment of moderate to severe atopic dermatitis in children who failed to respond adequately to conventional therapies such as topical corticosteroids. Maintenance treatment Treatment of moderate to severe atopic dermatitis for the prevention of flares and the prolongation of flare-free intervals in patients experiencing a high frequency of disease exacerbations (i.e. occurring 4 or more times per year) who have had an initial response to a maximum of 6 weeks treatment of twice daily tacrolimus ointment (lesions cleared, almost cleared or mildly affected).
Tacrolimus. Due to the theoretical risk of skin cancer exposure of the skin to sunlight should be minimised and the use of ultraviolet (UV) light from a solarium, therapy with UVB or UVA in combination with psoralens (PUVA) should be avoided during use of tacrolimus oint. • Emollients should not be applied to the same area within 2 hours of applying tacrolimus oint. Before commencing treatment with topical tacrolimus, clinical infections at treatment sites should be cleared. • Transplant patients receiving immunosuppressive regimens (e.g. systemic tacrolimus) are at increased risk for developing lymphoma; therefore patients who receive topical tacrolimus and who develop lymphadenopathy should be monitored to ensure that the lymphadenopathy resolves. In the absence of a clear aetiology for the lymphadenopathy or in the presence of acute infectious mononucleosis, discontinuation of Protopic should be considered. • Tacrolimus ointment should be used with caution in patients with hepatic failure. • Tacrolimus oint should not be used in patients with Xxxxxxxxx’x Syndrome (rare epidermal barrier defect).
Tacrolimus. Formal topical drug interaction studies with tacrolimus ointment have not been conducted. Tacrolimus is not metabolised in human skin, indicating that there is no potential for percutaneous interactions that could affect the metabolism of tacrolimus. There is no experience of concomitant use of systemic steroids or immunosuppressive agents.

Related to Tacrolimus

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