Common use of Workflow Clause in Contracts

Workflow. Automatic positioning system Couch integrated Typical repositioning time < 3 s Typical collimator size setup time < 3 s Blocked collimation setup time < 3 s Mixed collimation setup time (Composite shot) < 3 s Check and verify 100% QA procedure Automatic Accuracy Radiological accuracy < 0.5 mm Positioning repeatability < 0.05 mm Maximum patient weight 210 kg (460 pounds) Treatment planning Treatment planning system PC/Linux based Dynamic shaping Yes Remote planning Yes Image co-registration Yes PET supported Yes Mechanical treatment range X/Y/Z 160/180/220 mm Shape of accessible volume Cylindrical Real collimator sizes 4,8,16 mm diameter Radiation data Total cobalt-60 activity at loading (approx.) < 6,600 Xxxxx (2.44 x 1014 Bq) Number of radiation sources 192 Radiation dose rate at focal point at loading > 3 Gy/min Physical data Overall length, including cover 4.46 m Overall width, including cover 2.12 m Overall height, including cover 1.91 m Total weight (approximate) 20,000 kg Exhibit 10.22b Radiation unit The radiation unit is the radiation delivery system. It houses 192 Cobalt-60 sources and the collimator system that directs the radiation to the focus point. The radiation unit incorporates the management of the shielding doors and electro-mechanics of the source sectors. The following section describes selected components within the radiation unit. All components are chosen from well-recognized suppliers to secure reliability and to optimize performance of the system. Collimator body with radiation shielding Collimator body Tungsten body with 576 collimator channels. Collimators Tungsten collimator inserts. Pre-collimator 576 lead pre-collimator channels. Outer shielding Cast iron. Inner shielding Tungsten and lead. Bearing for collimator body Crossed roller bearing. Static axial load 680000 N Shielding doors Steel. Shielding strips Stainless Steel. Servo Controller High precision, fully digital servo drive with embedded intelligence. Motor DC motor with 2000 line encoder Linear guide Linear guide blocks Caged ball technology. Gear Planetary gear Clutch Ratchetting clutch 8 source carrying sector units Sector Aluminum. 24 source housing Shafts Induction hardened stainless steel. Bearings Graphite bushings Motor 24V DC motor Encoder 500 impulses/turn Linear guide unit Repeatability: ±0.003mm. Linear encoder Absolute Linear encoder. Solenoid Photo-micro sensor. Servo controllers Intelligent servo card Exhibit 10.22b Patient Positioning System The Patient Positioning System is the component of the PERFEXION™ system that the patient reclines on for treatment and is positioned relative the point of focus in the radiation unit. The following section describes selected components within the Patient Positioning System. All components are chosen from well-recognized suppliers to secure reliability and to optimize the performance of Leksell Gamma Knife PERFEXION. Couch framework with X/Y/Z drive Framework 20 mm zinc chromated steel Motors DC motors with 2000 line encoders. Gear X/Y-axis Planetary gear 30:1 Z-axis Planetary gear 4:1 Ball screws Bearing houses Support bearings X/Z -axis. Screw xxxx Y-axis: Integrated safety nut. Linear guides Linear guide blocks Caged ball technology. Solenoid Y-axis: Photo-micro sensor. Linear encoders Absolute Linear encoders. Accuracy grade +/- 0.005mm. Servo Controllers High precision, fully digital servo drive, with embedded intelligence. Frame fixation Hardened stainless steel Comfort system Mattress support Sandwich structure with aluminum honeycomb core and steel sheets Actuator DC actuator Ball bearing Stainless steel.

Workflow. Automatic positioning system Couch integrated Typical repositioning time < 3 s Typical collimator size setup time < 3 s Blocked collimation setup time < 3 s Mixed collimation setup time (Composite shot) < 3 s Check and verify 100% QA procedure Automatic Accuracy Radiological accuracy < 0.5 mm Positioning repeatability < 0.05 mm Maximum patient weight 210 kg (460 pounds) Treatment planning Treatment planning system PC/Linux based Dynamic shaping Yes Remote planning Yes Image co-registration Yes PET supported Yes Mechanical treatment range X/Y/Z 160/180/220 mm Shape of accessible volume Cylindrical Real collimator sizes 4,8,16 mm diameter Radiation data Total cobalt-60 activity at loading (approx.) < 6,600 Xxxxx (2.44 x 1014 Bq) Number of radiation sources 192 Radiation dose rate at focal point at loading > 3 Gy/min Physical data Overall length, including cover 4.46 m Overall width, including cover 2.12 m Overall height, including cover 1.91 m Total weight (approximate) 20,000 kg Exhibit 10.22b Radiation unit The radiation unit is the radiation delivery system. It houses 192 Cobalt-60 sources and the collimator system that directs the radiation to the focus point. The radiation unit incorporates the management of the shielding doors and electro-mechanics of the source sectors. The following section describes selected components within the radiation unit. All components are chosen from well-recognized suppliers to secure reliability and to optimize performance of the system. Collimator body with radiation shielding Collimator body Tungsten body with 576 collimator channels. Collimators Tungsten collimator inserts. Pre-collimator 576 lead pre-collimator channels. Outer shielding Cast iron. Inner shielding Tungsten and lead. Bearing for collimator body Crossed roller bearing. Static axial load 680000 N Shielding doors Steel. Shielding strips Stainless Steel. Servo Controller High precision, fully digital servo drive with embedded intelligence. Motor DC motor with 2000 line encoder Linear guide Linear guide blocks Caged ball technology. Gear Planetary gear Clutch Ratchetting clutch 8 source carrying sector units Sector Aluminum. 24 source housing Shafts Induction hardened stainless steel. Bearings Graphite bushings Motor 24V DC motor Encoder 500 impulses/turn Linear guide unit Repeatability: ±0.003mm. Linear encoder Absolute Linear encoder. Solenoid Photo-micro sensor. Servo controllers Intelligent servo card Exhibit 10.22b Patient Positioning System The Patient Positioning System is the component of the PERFEXION™ system that the patient reclines on for treatment and is positioned relative the point of focus in the radiation unit. The following section describes selected components within the Patient Positioning System. All components are chosen from well-recognized suppliers to secure reliability and to optimize the performance of Leksell Gamma Knife PERFEXION. Couch framework with X/Y/Z drive Framework 20 mm zinc chromated steel Motors DC motors with 2000 line encoders. Gear X/Y-axis Planetary gear 30:1 Z-axis Planetary gear 4:1 Ball screws Bearing houses Support bearings X/Z -axis. Screw xxxx Y-axis: Integrated safety nut. Linear guides Linear guide blocks Caged ball technology. Solenoid Y-axis: Photo-micro sensor. Linear encoders Absolute Linear encoders. Accuracy grade +/- 0.005mm. Servo Controllers High precision, fully digital servo drive, with embedded intelligence. Frame fixation Hardened stainless steel Comfort system Mattress support Sandwich structure with aluminum honeycomb core and steel sheets Actuator DC actuator Ball bearing Stainless steel.card

Workflow. Automatic positioning system Couch integrated Typical repositioning time < 3 s Typical collimator size setup time < 3 s Blocked collimation setup time < 3 s Mixed collimation setup time (Composite shot) < 3 s Check and verify 100% QA procedure Automatic Accuracy Radiological accuracy < 0.5 mm Positioning repeatability < 0.05 mm Maximum patient weight 210 kg (460 pounds) Treatment planning Treatment planning system PC/Linux based Dynamic shaping Yes Remote planning Yes Image co-registration Yes PET supported Yes Mechanical treatment range X/Y/Z 160/180/220 mm Shape of accessible volume Cylindrical Real collimator sizes 4,8,16 mm diameter Radiation data Total cobalt-60 activity at loading (approx.) < 6,600 Xxxxx Cxxxx (2.44 x 1014 Bq) Number of radiation sources 192 Radiation dose rate at focal point at loading > 3 Gy/min Physical data Overall length, including cover 4.46 m Overall width, including cover 2.12 m Overall height, including cover 1.91 m Total weight (approximate) 20,000 kg Exhibit 10.22b Radiation unit The radiation unit is the radiation delivery system. It houses 192 Cobalt-60 sources and the collimator system that directs the radiation to the focus point. The radiation unit incorporates the management of the shielding doors and electro-mechanics of the source sectors. The following section describes selected components within the radiation unit. All components are chosen from well-recognized suppliers to secure reliability and to optimize performance of the system. Collimator body with radiation shielding Collimator body Tungsten body with 576 collimator channels. Collimators Tungsten collimator inserts. Pre-collimator 576 lead pre-collimator channels. Outer shielding Cast iron. Inner shielding Tungsten and lead. Bearing for collimator body Crossed roller bearing. Static axial load 680000 N Shielding doors Steel. Shielding strips Stainless Steel. Servo Controller High precision, fully digital servo drive with embedded intelligence. Motor DC motor with 2000 line encoder Linear guide Linear guide blocks Caged ball technology. Gear Planetary gear Clutch Ratchetting clutch 8 source carrying sector units Sector Aluminum. 24 source housing Shafts Induction hardened stainless steel. Bearings Graphite bushings Motor 24V DC motor Encoder 500 impulses/turn Linear guide unit Repeatability: ±0.003mm. Linear encoder Absolute Linear encoder. Solenoid Photo-micro sensor. Servo controllers Intelligent servo card Exhibit 10.22b Patient Positioning System The Patient Positioning System is the component of the PERFEXION™ system that the patient reclines on for treatment and is positioned relative the point of focus in the radiation unit. The following section describes selected components within the Patient Positioning System. All components are chosen from well-recognized suppliers to secure reliability and to optimize the performance of Leksell Gamma Knife PERFEXION. Couch framework with X/Y/Z drive Framework 20 mm zinc chromated steel Motors DC motors with 2000 line encoders. Gear X/Y-axis Planetary gear 30:1 Z-axis Planetary gear 4:1 Ball screws Bearing houses Support bearings X/Z -axis. Screw xxxx Y-axis: Integrated safety nut. Linear guides Linear guide blocks Caged ball technology. Solenoid Y-axis: Photo-micro sensor. Linear encoders Absolute Linear encoders. Accuracy grade +/- 0.005mm. Servo Controllers High precision, fully digital servo drive, with embedded intelligence. Frame fixation Hardened stainless steel Comfort system Mattress support Sandwich structure with aluminum honeycomb core and steel sheets Actuator DC actuator Ball bearing Stainless steel.10.22b

Workflow. Automatic positioning system Couch integrated Typical repositioning time < 3 s Typical collimator size setup time < 3 s Blocked collimation setup time < 3 s Mixed collimation setup time (Composite shot) < 3 s Check and verify 100% QA procedure Automatic Accuracy Radiological accuracy < 0.5 mm Positioning repeatability < 0.05 mm Maximum patient weight 210 kg (460 pounds) Treatment planning Treatment planning system PC/Linux based Dynamic shaping Yes Remote planning Yes Image co-registration Yes PET supported Yes Mechanical treatment range X/Y/Z 160/180/220 mm Shape of accessible volume Cylindrical Real collimator sizes 4,8,16 mm diameter Radiation data Total cobalt-60 activity at loading (approx.) < 6,600 Xxxxx Cxxxx (2.44 x 1014 Bq) Number of radiation sources 192 Radiation dose rate at focal point at loading > 3 Gy/min Physical data Overall length, including cover 4.46 m Overall width, including cover 2.12 m Overall height, including cover 1.91 m Total weight (approximate) 20,000 kg Exhibit 10.22b Radiation unit The radiation unit is the radiation delivery system. It houses 192 Cobalt-60 sources and the collimator system that directs the radiation to the focus point. The radiation unit incorporates the management of the shielding doors and electro-mechanics of the source sectors. The following section describes selected components within the radiation unit. All components are chosen from well-recognized suppliers to secure reliability and to optimize performance of the system. Collimator body with radiation shielding Collimator body Tungsten body with 576 collimator channels. Collimators Tungsten collimator inserts. Pre-collimator 576 lead pre-collimator channels. Outer shielding Cast iron. Inner shielding Tungsten and lead. Bearing for collimator body Crossed roller bearing. Static axial load 680000 N Shielding doors Steel. Shielding strips Stainless Steel. Servo Controller High precision, fully digital servo drive with embedded intelligence. Motor DC motor with 2000 line encoder Linear guide Linear guide blocks Caged ball technology. Gear Planetary gear Clutch Ratchetting clutch 8 source carrying sector units Sector Aluminum. 24 source housing Shafts Induction hardened stainless steel. Bearings Graphite bushings Motor 24V DC motor Encoder 500 impulses/turn Linear guide unit Repeatability: ±0.003mm. Linear encoder Absolute Linear encoder. Solenoid Photo-micro sensor. Servo controllers Intelligent servo card Exhibit 10.22b Patient Positioning System The Patient Positioning System is the component of the PERFEXION™ PERFEXIONTM system that the patient reclines on for treatment and is positioned relative the point of focus in the radiation unit. The following section describes selected components within the Patient Positioning System. All components are chosen from well-recognized suppliers to secure reliability and to optimize the performance of Leksell Gamma Knife PERFEXION. Couch framework with X/Y/Z drive Framework 20 mm zinc chromated steel Motors DC motors with 2000 line encoders. Gear X/Y-axis Planetary gear 30:1 Z-axis Planetary gear 4:1 Ball screws Bearing houses Support bearings X/Z -axis. Screw xxxx jxxx Y-axis: Integrated safety nut. Linear guides Linear guide blocks Caged ball technology. Solenoid Y-axis: Photo-micro sensor. Linear encoders Absolute Linear encoders. Accuracy grade +/- 0.005mm. Servo Controllers High precision, fully digital servo drive, with embedded intelligence. Frame fixation Hardened stainless steel Comfort system Mattress support Sandwich structure with aluminum honeycomb core and steel sheets Actuator DC actuator Ball bearing Stainless steel.