No. CS-1 October 30, 2003 PREDIX PHARMACEUTICALS HOLDINGS, INC. WARRANT FOR NEW COMMON STOCK THIS CERTIFIES THAT, for value received, RRD International, LLC, or its registered assigns (the "Holder"), is entitled, subject to the vesting provisions set...EPIX Pharmaceuticals, Inc. • November 9th, 2006 • In vitro & in vivo diagnostic substances • Delaware
INDEX" - The Consumer Price Index (including fruits and vegetables) that is published by the Central Statistics Office (the "OFFICE"). "THE BASIC INDEX" - The Index that was published on September 15, 2004 for the month of August 2004. "LINKED"...Management Agreement • November 9th, 2006 • EPIX Pharmaceuticals, Inc. • In vitro & in vivo diagnostic substances
RECITALSLease • March 11th, 2005 • EPIX Pharmaceuticals, Inc. • In vitro & in vivo diagnostic substances
METASYN, INC.Stock Purchase Agreement • December 10th, 1996 • Epix Medical Inc • Massachusetts
Exhibit 4.4 NEITHER THIS WARRANT NOR THE SECURITIES ISSUABLE UPON EXERCISE OF THIS WARRANT HAVE BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED. NO SALE OR DISPOSITION MAY BE EFFECTED EXCEPT IN COMPLIANCE WITH RULE 144 UNDER SAID ACT OR...EPIX Pharmaceuticals, Inc. • November 9th, 2006 • In vitro & in vivo diagnostic substances • Delaware
Exhibit 10.48 SECURITY AGREEMENT THIS SECURITY AGREEMENT (the "Security Agreement") is entered into as of October 8, 1999, between Epix Medical, Inc., a Delaware corporation, with its principal executive offices in Cambridge, Massachusetts (the...Security Agreement • March 20th, 2000 • Epix Medical Inc • In vitro & in vivo diagnostic substances • New York
Exhibit 10.29 EPIX PHARMACEUTICALS, INC. FORM OF INDEMNIFICATION AGREEMENT This Agreement dated _______________ is between EPIX Pharmaceuticals, Inc. (the "Company"), a Delaware corporation, and ________________ (the "Indemnitee"), who is an [officer]...Indemnification Agreement • March 11th, 2005 • EPIX Pharmaceuticals, Inc. • In vitro & in vivo diagnostic substances • Delaware
Exhibit 10.15 NEITHER THIS WARRANT NOR THE SHARES OF STOCK ISSUABLE UPON EXERCISE HEREOF HAVE BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED. NO SALE, TRANSFER OR OTHER DISPOSITION OF THIS WARRANT OR SAID SHARES MAY BE EFFECTED WITHOUT...Epix Medical Inc • December 10th, 1996 • Massachusetts
COMMON STOCK PURCHASE AGREEMENT DATED AS OF SEPTEMBER 18, 2000Common Stock Purchase Agreement • September 18th, 2000 • Epix Medical Inc • In vitro & in vivo diagnostic substances • New York
SECOND AMENDMENT LEASE FROM TRUSTEES OF THE CAMBRIDGE EAST TRUST TO METASYN, INC.Lease • December 10th, 1996 • Epix Medical Inc
COMMON STOCKStock Purchase Agreement • June 29th, 2000 • Epix Medical Inc • In vitro & in vivo diagnostic substances • Delaware
LEASEEPIX Pharmaceuticals, Inc. • November 9th, 2006 • In vitro & in vivo diagnostic substances
FIRST AMENDMENT TO LICENSE AGREEMENTLicense Agreement • April 10th, 2007 • EPIX Pharmaceuticals, Inc. • Pharmaceutical preparations
AMENDMENT AGREEMENT This Amendment Agreement made this 15th day of Sept., 1994 by and between the following parties: SUMITOMO CORPORATION, a Japanese corporation with its principal place of business located at 2-2, Hitosubashi 1-chome, Chiyoda-ku,...Amendment Agreement • January 27th, 1997 • Epix Medical Inc • In vitro & in vivo diagnostic substances
METASYN, INC.Purchase Agreement • December 10th, 1996 • Epix Medical Inc • Massachusetts
LESSEE: METASYN, INC.Master Lease Agreement • December 10th, 1996 • Epix Medical Inc
WITNESSETHLicense Agreement • December 10th, 1996 • Epix Medical Inc • Massachusetts
LEASEEPIX Pharmaceuticals, Inc. • August 7th, 2008 • Pharmaceutical preparations
METASYN, INC.Purchase Agreement • December 10th, 1996 • Epix Medical Inc • Massachusetts
LEASE ----- WITH THIRD AMENDMENT --------------------Lease • December 10th, 1996 • Epix Medical Inc
SHORT FORM LEASE TRUSTEES OF THE CAMBRIDGE EAST TRUST TO EPIX MEDICAL, INC. AT 63 Rear, 65 Rear, 69, 71 and 75 ROGERS STREET, CAMBRIDGE, MASSACHUSETTSEpix Medical Inc • October 21st, 1997 • In vitro & in vivo diagnostic substances
EXTENSION AGREEMENTExtension Agreement • January 27th, 1997 • Epix Medical Inc • In vitro & in vivo diagnostic substances
WITNESSETH:Standstill Agreement • June 29th, 2000 • Epix Medical Inc • In vitro & in vivo diagnostic substances • Delaware
EXHIBIT 10.2 STOCK PURCHASE AGREEMENT BY AND BETWEEN EPIX PHARMACEUTICALS, INC.Stock Purchase Agreement • January 18th, 2007 • EPIX Pharmaceuticals, Inc. • In vitro & in vivo diagnostic substances • New York
EXHIBIT 10.3License Agreement • November 9th, 2006 • EPIX Pharmaceuticals, Inc. • In vitro & in vivo diagnostic substances
WITNESSETH:Employment Agreement • November 9th, 2006 • EPIX Pharmaceuticals, Inc. • In vitro & in vivo diagnostic substances • Massachusetts
EXHIBIT 99.1 RETENTION AGREEMENT ------------------- July 25, 2006 Robert Pelletier [ADDRESS] Dear Bob: The purpose of this Retention Agreement (hereinafter the Agreement) is to confirm the terms of your resignation from EPIX Pharmaceuticals, Inc....Retention Agreement • July 26th, 2006 • EPIX Pharmaceuticals, Inc. • In vitro & in vivo diagnostic substances • Massachusetts
RECITALSSettlement and Release Agreement • September 25th, 2001 • Epix Medical Inc • In vitro & in vivo diagnostic substances • New York
Exhibit 10.30 FORM OF AMENDMENT TO STOCK OPTION AGREEMENT This AMENDMENT is made as of the 17th day of April, 2003 (the "Effective Date") to the Notice of Grant of Stock Options and Option Agreement, a copy of which is annexed hereto as EXHIBIT A (the...Stock Option Agreement • March 11th, 2005 • EPIX Pharmaceuticals, Inc. • In vitro & in vivo diagnostic substances
Exhibit 10.1 RELEASE AGREEMENT Dated this 5th day of April, 2007 Between: DR. OREN BECKER Identity no. 056528177 Residing at 12 Motza Haktana Street, Mevaseret Zion, Israel ("Oren Becker ")Release Agreement • April 6th, 2007 • EPIX Pharmaceuticals, Inc. • Pharmaceutical preparations • Delaware
BETWEEN AMGEN INC. ANDLicense Agreement • November 9th, 2006 • EPIX Pharmaceuticals, Inc. • In vitro & in vivo diagnostic substances • Delaware
Exhibit 10.9 NEITHER THIS WARRANT NOR THE SHARES OF STOCK ISSUABLE UPON EXERCISE HEREOF HAVE BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED. NO SALE, TRANSFER OR OTHER DISPOSITION OF THIS WARRANT OR SAID SHARES MAY BE EFFECTED WITHOUT...Epix Medical Inc • December 10th, 1996 • Massachusetts
WITNESSETH:Employment Agreement • November 9th, 2006 • EPIX Pharmaceuticals, Inc. • In vitro & in vivo diagnostic substances • Massachusetts
SHORT FORM LEASEEpix Medical Inc • December 10th, 1996 • Massachusetts
EXHIBIT 10.11 BIO-I.T. (BIO INFORMATION TECHNOLOGIES) LTD. EMPLOYMENT AGREEMENTEscrow Agreement • November 9th, 2006 • EPIX Pharmaceuticals, Inc. • In vitro & in vivo diagnostic substances
