Transkaryotic Therapies Inc Sample Contracts

COMMON STOCK
Underwriting Agreement • December 21st, 2001 • Transkaryotic Therapies Inc • Biological products, (no disgnostic substances) • New York
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Standard Contracts

LEASE
Lease Agreement • November 14th, 2000 • Transkaryotic Therapies Inc • Biological products, (no disgnostic substances) • Massachusetts
BACKGROUND
Purchase and Sale Agreement • April 2nd, 2001 • Transkaryotic Therapies Inc • Biological products, (no disgnostic substances) • Massachusetts
R E C I T A L S
Registration Rights Agreement • August 14th, 2000 • Transkaryotic Therapies Inc • Biological products, (no disgnostic substances) • Delaware
TRUSTEE INDENTURE
Indenture • May 2nd, 2005 • Transkaryotic Therapies Inc • Biological products, (no disgnostic substances) • New York
1 EXHIBIT 10.34 CONFIDENTIAL MATERIAL OMITTED AND FILED SEPARATELY WITH THE SECURITIES AND EXCHANGE COMMISSION. ASTERISKS DENOTE SUCH OMISSIONS. LICENSE AGREEMENT
License Agreement • October 16th, 1996 • Transkaryotic Therapies Inc • Biological products, (no disgnostic substances) • Delaware
ARTICLE I.
Lease Agreement • March 31st, 1999 • Transkaryotic Therapies Inc • Biological products, (no disgnostic substances) • Massachusetts
EXHIBIT 1.1 Transkaryotic Therapies, Inc. 1.25% Convertible Senior Notes due May 15, 2011 Underwriting Agreement
Underwriting Agreement • April 29th, 2004 • Transkaryotic Therapies Inc • Biological products, (no disgnostic substances) • New York
AND
Rights Agreement • December 14th, 2000 • Transkaryotic Therapies Inc • Biological products, (no disgnostic substances) • Delaware
FORM OF SUBORDINATED INDENTURE
Subordinated Indenture • December 13th, 2000 • Transkaryotic Therapies Inc • Biological products, (no disgnostic substances) • New York
INDEMNIFICATION AGREEMENT
Indemnification Agreement • May 15th, 2003 • Transkaryotic Therapies Inc • Biological products, (no disgnostic substances) • Delaware

This Agreement is made as of the 30th day of April 2003, by and between Transkaryotic Therapies, Inc., a Delaware corporation (the “Corporation”), and Michael J. Astrue (the “Indemnitee”), a director and an officer of the Corporation.

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PLACEMENT AGREEMENT ---------------------------
Placement Agreement • July 24th, 1997 • Transkaryotic Therapies Inc • Biological products, (no disgnostic substances) • California
FORM OF SENIOR INDENTURE
Senior Indenture • December 13th, 2000 • Transkaryotic Therapies Inc • Biological products, (no disgnostic substances) • New York
Exhibit 10.30 REIMBURSEMENT AGREEMENT This REIMBURSEMENT AGREEMENT is made as of May 18, 2000, by and between Transkaryotic Therapies, Inc., a Delaware corporation (the "Company") and William H. Pursley (the "Borrower"). WHEREAS, the Borrower has been...
Reimbursement Agreement • April 2nd, 2001 • Transkaryotic Therapies Inc • Biological products, (no disgnostic substances)

This REIMBURSEMENT AGREEMENT is made as of May 18, 2000, by and between Transkaryotic Therapies, Inc., a Delaware corporation (the "Company") and William H. Pursley (the "Borrower").

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Asterisks denote omissions. COMMERCIAL SUPPLY AND PROCESS VALIDATION AGREEMENT
Commercial Supply Agreement • April 7th, 2003 • Transkaryotic Therapies Inc • Biological products, (no disgnostic substances) • Maryland

THIS COMMERCIAL SUPPLY AGREEMENT (the “Agreement”) is entered into as of this 6th day of December, 1999 by and between TRANSKARYOTIC THERAPIES, INC.,(“TKT”), a Delaware corporation having an address at 195 Albany Street, Cambridge, MA 02139, and CHESAPEAKE BIOLOGICAL LABORATORIES, INC., a Maryland corporation having an address at 1111 South Paca Street, Baltimore, MD 21230 (“CBL”), with respect to the following:

AGREEMENT AND PLAN OF MERGER
Merger Agreement • April 27th, 2005 • Transkaryotic Therapies Inc • Biological products, (no disgnostic substances) • Delaware

AGREEMENT AND PLAN OF MERGER (this “Agreement”) dated as of April 21, 2005, among Transkaryotic Therapies, Inc., a Delaware corporation (the “Company”), Shire Pharmaceuticals Group plc, a public limited company incorporated under the laws of England and Wales (“Parent”), and Sparta Acquisition Corporation, a Delaware corporation and a wholly-owned subsidiary of Parent (“Merger Subsidiary”).

EMPLOYMENT AGREEMENT
Employment Agreement • March 29th, 2002 • Transkaryotic Therapies Inc • Biological products, (no disgnostic substances) • Massachusetts

AGREEMENT, dated as of March 18, 2001, between Transkaryotic Therapies, Inc., a Delaware corporation (the “Company”), and Renato Fuchs (the “Executive”).

LICENSE AGREEMENT
License Agreement • December 19th, 2002 • Transkaryotic Therapies Inc • Biological products, (no disgnostic substances) • Delaware
RECITALS
Purchase and Sale and Assignment Agreement • April 2nd, 2001 • Transkaryotic Therapies Inc • Biological products, (no disgnostic substances)
INDEMNIFICATION AGREEMENT
Indemnification Agreement • May 15th, 2003 • Transkaryotic Therapies Inc • Biological products, (no disgnostic substances)

This Agreement is made as of the 13th day of March 2003, by and between Transkaryotic Therapies, Inc., a Delaware corporation (the “Corporation”), and Daniel E. Geffken (the “Indemnitee”), an officer of the Corporation.

EXHIBIT 10.1 CONFIDENTIAL MATERIALS OMITTED AND FILED SEPARATELY WITH THE SECURITIES AND EXCHANGE COMMISSION. ASTERISKS DENOTE OMISSIONS. AMENDED AND RESTATED LICENSE AGREEMENT
License Agreement • May 10th, 2004 • Transkaryotic Therapies Inc • Biological products, (no disgnostic substances) • Delaware
TRANSKARYOTIC THERAPIES, INC. 700 Main Street Cambridge, MA 02139 Phone: (617) 349-0200 April 21, 2005
Resignation Agreement • April 27th, 2005 • Transkaryotic Therapies Inc • Biological products, (no disgnostic substances)

This letter is to confirm our agreement that, effective as of the date of this letter, you hereby resign as an officer and an employee of Transkaryotic Therapies, Inc.(the “Company”) and as a member of the Board of Directors of the Company.

April 28, 2003
Severance Agreement • August 12th, 2003 • Transkaryotic Therapies Inc • Biological products, (no disgnostic substances) • Massachusetts

In connection with the termination of your employment with Transkaryotic Therapies, Inc., (the “Company”) on June 30, 2003, you are eligible to receive the severance benefits described in the “Description of Severance Benefits” attached to this letter as Attachment A if you sign and return this letter agreement to Linda Pettingell by May 23, 2003. By signing and returning this letter agreement, you will be entering into a binding agreement with the Company and will be agreeing to the terms and conditions set forth in the numbered paragraphs below, including the release of claims set forth in paragraph 3. Therefore, you are advised to consult with your attorney before signing this letter agreement and you may take up to twenty-one (21) days to do so. If you sign this letter agreement, you may change your mind and revoke your agreement during the seven (7) day period after you have signed it by notifying Linda Pettingell of your revocation in writing. If you do not so revoke, this letter

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