EXHIBIT 4.8 VOID AFTER 5:00 P.M., NEW YORK CITY TIME, ON DECEMBER 31, 2007 THIS WARRANT AND THE SHARES ISSUABLE UPON EXERCISE OF THIS WARRANT HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE "SECURITIES ACT"), OR THE...Warrant Agreement • January 29th, 2003 • Inkine Pharmaceutical Co Inc • Pharmaceutical preparations • New York
Common Stock ($0.0001 Par Value)Underwriting Agreement • December 16th, 2003 • Inkine Pharmaceutical Co Inc • Pharmaceutical preparations • New York
REGISTRATION RIGHTS AGREEMENT This REGISTRATION RIGHTS AGREEMENT (this "Agreement") is dated as of October 1, 2002, by and among InKine Pharmaceutical Company, Inc., a corporation organized under the laws of the State of New York (the "Company"), and...Registration Rights Agreement • October 8th, 2002 • Inkine Pharmaceutical Co Inc • Pharmaceutical preparations • New York
AGREEMENT AND PLAN OF REORGANIZATIONMerger Agreement • November 21st, 1997 • Inkine Pharmaceutical Co Inc • Pharmaceutical preparations • Delaware
RECITALSPurchase Agreement • October 20th, 1999 • Inkine Pharmaceutical Co Inc • Pharmaceutical preparations • New York
WITNESSETH:Subscription Agreement • May 17th, 2000 • Inkine Pharmaceutical Co Inc • Pharmaceutical preparations • New York
BACKGROUNDSecurity Agreement • October 8th, 2002 • Inkine Pharmaceutical Co Inc • Pharmaceutical preparations • New York
1 Exhibit 4.2 REGISTRATION RIGHTS AGREEMENT This Registration Rights Agreement (the "Agreement") is made and entered into as of this 20th day of September, 1999 by and between InKine Pharmaceutical Company, Inc., a New York corporation (the...Registration Rights Agreement • October 20th, 1999 • Inkine Pharmaceutical Co Inc • Pharmaceutical preparations • New York
BACKGROUNDRegistration Rights Agreement • November 21st, 1997 • Inkine Pharmaceutical Co Inc • Pharmaceutical preparations • Delaware
EXECUTION COPY SECURITIES PURCHASE AGREEMENT This SECURITIES PURCHASE AGREEMENT (this "Agreement"), is dated as of December 16, 2002, by and among InKine Pharmaceutical Company, Inc., a corporation organized under the laws of the State of New York...Securities Purchase Agreement • December 19th, 2002 • Inkine Pharmaceutical Co Inc • Pharmaceutical preparations • New York
ANDStock Purchase Agreement • November 21st, 1997 • Inkine Pharmaceutical Co Inc • Pharmaceutical preparations • Pennsylvania
1 Exhibit 10.19 SEVERANCE AGREEMENT This Severance Agreement (the "Agreement") is dated November 3, 1999, between InKine Pharmaceutical Company, Inc. (the "Company") and Taffy J. Williams ("Williams"). Williams has been employed by the Company since...Severance Agreement • February 14th, 2000 • Inkine Pharmaceutical Co Inc • Pharmaceutical preparations • Pennsylvania
Exhibit 4.1 SECURITIES PURCHASE AGREEMENT SECURITIES PURCHASE AGREEMENT (this "Agreement"), dated as of June 15, 2001, among InKine Pharmaceutical Company, Inc., a corporation organized under the laws of the State of New York (the "Company"), and the...Securities Purchase Agreement • June 19th, 2001 • Inkine Pharmaceutical Co Inc • Pharmaceutical preparations • New York
AMENDMENT TO RESTATED AND AMENDED MANAGEMENT SERVICES AGREEMENTManagement Services Agreement • October 14th, 1997 • Panax Pharmaceutical Co LTD • Pharmaceutical preparations
WITNESSETH:Subscription Agreement • January 29th, 2003 • Inkine Pharmaceutical Co Inc • Pharmaceutical preparations • New York
EXECUTION COPY REGISTRATION RIGHTS AGREEMENT This REGISTRATION RIGHTS AGREEMENT (this "Agreement"), is dated as of December 17, 2002, by and among InKine Pharmaceutical Company, Inc., a corporation organized under the laws of the State of New York...Registration Rights Agreement • December 19th, 2002 • Inkine Pharmaceutical Co Inc • Pharmaceutical preparations • New York
EMPLOYMENT AGREEMENT EMPLOYMENT AGREEMENT (the "Agreement") dated as of December 1, 2000 between INKINE PHARMACEUTICAL COMPANY, INC., a New York corporation ("Employer"), and MARTIN ROSE, M.D., J.D. ("Employee") Background. Employee has been employed...Employment Agreement • February 25th, 2004 • Inkine Pharmaceutical Co Inc • Pharmaceutical preparations • Pennsylvania
BACKGROUNDSecurity Agreement • December 19th, 2002 • Inkine Pharmaceutical Co Inc • Pharmaceutical preparations • New York
BACKGROUNDRestructuring Agreement • October 8th, 2002 • Inkine Pharmaceutical Co Inc • Pharmaceutical preparations • New York
EXHIBIT 4.1 CONVERSION AGREEMENT This CONVERSION AGREEMENT (this "Agreement") is dated as of June 30, 2003, by and among InKine Pharmaceutical Company, Inc., a corporation organized under the laws of the State of New York (the "Company"), S.A.C....Conversion Agreement • July 15th, 2003 • Inkine Pharmaceutical Co Inc • Pharmaceutical preparations • New York
2 3 balance of the term set forth in such option, warrant or right, and otherwise in accordance with the term(s) thereof.Employment Agreement • September 28th, 1999 • Inkine Pharmaceutical Co Inc • Pharmaceutical preparations • Pennsylvania
AMENDMENT TO EMPLOYMENT AGREEMENT Amendment dated November 20, 2003 to Employment Agreement dated as of November 2, 1998 between InKine Pharmaceutical Company, Inc. a New York corporation ("Employer") and Robert F. Apple ("Employee"). Employer and...Employment Agreement • February 25th, 2004 • Inkine Pharmaceutical Co Inc • Pharmaceutical preparations
1 EXHIBIT 10.18 AMENDMENT TO EMPLOYMENT AGREEMENT Amendment dated November 4, 1999 to Employment Agreement dated as of November 6, 1997 between InKine Pharmaceutical Company, Inc. a New York corporation ("Employer") and Leonard S. Jacob ("Employee")....Employment Agreement • February 14th, 2000 • Inkine Pharmaceutical Co Inc • Pharmaceutical preparations
EMPLOYMENT AGREEMENT EMPLOYMENT AGREEMENT (the "Agreement") dated as of November 6, 1997, between INKINE PHARMACEUTICAL COMPANY, INC.., a New York corporation ("Employer"), and TAFFY J. WILLIAMS ("Employee"). Background. Employee has been employed by...Employment Agreement • November 21st, 1997 • Inkine Pharmaceutical Co Inc • Pharmaceutical preparations • Pennsylvania
EMPLOYMENT AGREEMENT EMPLOYMENT AGREEMENT (the "Agreement") dated as of November 6, 1997, between INKINE PHARMACEUTICAL COMPANY, INC., a New York corporation ("Employer"), and LEONARD S. JACOB ("Employee"). Background. Employer and Employee mutually...Employment Agreement • November 21st, 1997 • Inkine Pharmaceutical Co Inc • Pharmaceutical preparations • Pennsylvania
NEITHER THIS WARRANT NOR THE SHARES OF COMMON STOCK WHICH MAY BE PURCHASED HEREUNDER (COLLECTIVELY, THE "SECURITIES") HAS BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933 AS AMENDED (THE "SECURITIES ACT, OR APPLICABLE STATE SECURITIES LAWS, AND THE...Common Stock Purchase Warrant • November 21st, 1997 • Inkine Pharmaceutical Co Inc • Pharmaceutical preparations • New York
BY AND AMONGMerger Agreement • June 29th, 2005 • Inkine Pharmaceutical Co Inc • Pharmaceutical preparations • Delaware
NEITHER THIS WARRANT NOR THE SHARES OF COMMON STOCK WHICH MAY BE PURCHASED HEREUNDER (COLLECTIVELY, THE "SECURITIES") HAS BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933 AS AMENDED (THE "SECURITIES ACT, OR APPLICABLE STATE SECURITIES LAWS, AND THE...Common Stock Purchase Warrant • November 21st, 1997 • Inkine Pharmaceutical Co Inc • Pharmaceutical preparations • New York
1 CONSULTING AGREEMENT AGREEMENT, made this 14th day of February, 1997, by and between CRAIG ARONCHICK, M.D., residing at 903 Bryn Mawr Avenue, Penn Valley, Pennsylvania 19072 ("Consultant") and PANAX PHARMACEUTICAL COMPANY LTD., a New York...Consulting Agreement • March 13th, 1997 • Panax Pharmaceutical Co LTD • Pharmaceutical preparations • New York
1 THIS OPTION AND THE SHARES OF COMMON STOCK ISSUABLE UPON THE EXERCISE HEREOF HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933 OR ANY OTHER SECURITIES STATUTE, INCLUDING, WITHOUT LIMITATION, THE SECURITIES LAWS OF ANY STATE, AND IS SUBJECT...Option Agreement • March 13th, 1997 • Panax Pharmaceutical Co LTD • Pharmaceutical preparations
1 Pharmaceuticals, Inc. May 8, 1997 CorBec Pharmaceuticals, Inc. One Tower Bridge, Suite 1350 100 Front Street West Conshohocken, PA 19428 Attn: Hal Broderson Dear Hal: This letter of intent sets forth the basic terms and conditions under which Panax...Letter of Intent • May 15th, 1997 • Panax Pharmaceutical Co LTD • Pharmaceutical preparations
LICENSE AGREEMENT This License Agreement (this "Agreement") is made as of the 14th day of February, 1997 by and between PANAX PHARMACEUTICAL COMPANY, LTD. ("PANAX"), a New York Corporation having an office at 425 Park Avenue, New York, New York, 10022...License Agreement • March 13th, 1997 • Panax Pharmaceutical Co LTD • Pharmaceutical preparations • New York
NEITHER THIS WARRANT NOR THE SHARES OF COMMON STOCK WHICH MAY BE PURCHASED HEREUNDER (COLLECTIVELY, THE "SECURITIES") HAS BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933 AS AMENDED (THE "SECURITIES ACT, OR APPLICABLE STATE SECURITIES LAWS, AND THE...Common Stock Purchase Warrant • November 21st, 1997 • Inkine Pharmaceutical Co Inc • Pharmaceutical preparations • New York
