Activator Ligand or “AL” means a chemical entity selected and paired with a responsive gene construct which in the presence or absence of the chemical entity results in the expression of the protein encoded by such gene construct.
Activator Ligand means (i) veledimex and all formulations covered by the Drug Master File for a Formerly Licensed Product developed by Xxxxxxx, and (ii) changes to the subject matter described in the foregoing (i) and made by Xxxxxxx to advance a Formerly Licensed Product (“Alaunos Veledimex Alterations”). 1.7 “Affiliate” means, with respect to a particular Party or other entity, a person, corporation, partnership, or other entity that controls, is controlled by or is under common control with such Party or other entity. For the purposes of this definition, the word “control” (including, with correlative meaning, the terms “controlled by” or “under common control with”) means the actual power, either directly or indirectly through one or more intermediaries, to direct or cause the direction of the management and policies of such entity, whether by the ownership of fifty percent (50%) or more of the voting stock of such entity, or by contract or otherwise. 1.8 “Alaunos” has the meaning set forth in the preamble. 1.9 “Bankrupt Party” has the meaning set forth in Section 12.2(a). 1.10 “BCMA CAR Products” means any biological product, process or therapy developed under or arising from the B-cell maturation antigen (BCMA) CAR Program that is comprised of a CAR that is directed to BCMA, including all forms, formulations, presentations, doses, administrations and package configurations. 1.11 “BCMA CAR Program” means a program(s) of Research and Development focused on using CAR cells directed to BCMA. 1.12 “Business Day” means a day other than Saturday, Sunday or any day that banks in New York, New York, USA are required or permitted to be closed. 1.13 “CD19 CAR Products” means any biological product, process or therapy developed under or arising from the CD19 CAR Program that is comprised of a CAR that is directed to CD19, including all forms, formulations, presentations, doses, administrations and package configurations. CD19 CAR Products include all product candidates that previously were under Development by Xxxxxxx (and Precigen and its Affiliates) as of the Effective Date that contain a CAR that targets CD19. 1.14 “CD19 CAR Program” means a program(s) of Research and Development focused on using CAR cells directed to CD19. 1.15 “Chimeric Antigen Receptor” or “CAR” means [*****]. 1.16 “Chimeric Antigen Receptor T-Cell” or “CAR-T” means (i) [*****].
Activator Ligand means (i) veledimex and all formulations covered by the Drug Master File, (ii) changes to the subject matter described in (i) made by Ziopharm to advance a Licensed Product (“Ziopharm Veledimex Alterations”), and (iii) [*****] formulations of veledimex that include [*****] solely to the extent such formulations have been generated prior to the Effective Date.
Examples of Activator Ligand in a sentence
Precigen shall use commercially reasonable efforts to obtain any such consents required for the transfer of any such manufacturing related Information and, upon obtaining such consent, to transfer such manufacturing-related Licensed Know-How to Ziopharm to enable Ziopharm to manufacture Licensed Products, Activator Ligand and Accessory Material Agents.
Notwithstanding, but without limiting Section 4.1(a) or 4.5(c), Ziopharm acknowledges that the transfer of certain Licensed Know-How is related to the manufacture of Licensed Products, Activator Ligand, and Accessory Material Agents, including manufacturing and controls information and biologic manufacturing and process development technology, and such technology or Information may be subject to the consent of one or more Third Party contract manufactures.
The Activator Ligand (veledimex): An ecdysone analog, diacylhydrazine-based small molecule functions as an activator.
More Definitions of Activator Ligand
Activator Ligand means (i) veledimex and all formulations covered by the Drug Master File, (ii) changes to the subject matter described in (i) made by Ziopharm to advance a Licensed Product (“Ziopharm Veledimex Alterations”), and (iii) [*****] formulations of veledimex that include [*****] solely to the extent such formulations have been generated prior to the Effective Date. 1.10“Adenovirus Production Patents” means Schedules 5 and 6 of the Licensed Intellectual Property in Exhibit B. 1.11“Affiliate” means, with respect to a particular Party or other entity, a person, corporation, partnership, or other entity that controls, is controlled by or is under common control with such Party or other entity. For the purposes of this definition, the word “control” (including, with correlative meaning, the terms “controlled by” or “under common control with”) means the actual power, either directly or indirectly through one or more intermediaries, to direct or cause the direction of the management and policies of such entity, whether by the ownership of fifty percent (50%) or more of the voting stock of such entity, or by contract or otherwise. 1.12“Agreed Services” shall have the meaning set forth in Section 4.5(a). 1.13“Assigned Contracts” shall have the meaning set forth in Section 3.2(a). 1.14“Bankrupt Party” has the meaning set forth in Section 14.2(a). 1.15“[*****] CAR Products” means any biological product, process or therapy developed under or arising from the [*****] ([*****]) CAR Program that is comprised of a CAR that is directed to [*****], including all forms, formulations, presentations, doses, administrations and package configurations.
Activator Ligand means (i) veledimex and all formulations covered by the Drug Master File for a Formerly Licensed Product developed by Axxxxxx, and (ii) changes to the subject matter described in the foregoing (i) and made by Axxxxxx to advance a Formerly Licensed Product (“Alaunos Veledimex Alterations”).