Ex vivo definition

Ex vivo means outside of a living animal or human.
Ex vivo delivery shall mean the introduction, outside of the body of a human, of such compositions into a cell, tissue, organoid, or organ, followed by the administration of the cell, tissue, organoid, or organ which contains such introduced compositions into the body of the same (autologous) or different (allogeneic) human, without limitation as to the formulation, anatomic site, or route of administration or the use of encapsulation or other devices for such administration. “In Vivo” delivery shall mean the introduction of such compositions into an individual, without limitation as to the formulation, anatomic site, or route of administration or the use of encapsulation or other devices for such administration.
Ex vivo means that cells are extracted from a patient, corrected or otherwise modified by Gene Therapy, and transplanted or dosed back into patient.

Examples of Ex vivo in a sentence

  • Ex vivo programmed cell death and the prediction of response to chemotherapy.

  • Despite a modest 4-fold decrease in predicted IC50 for Q213K compared with wild type, FTSDYYKLY207-215 is still a strong binder to A*01:01.‌‌ Ex vivo IFN-g ELISpots in two A*03:01 and two B*27:05 convalescent donors confirmed loss of responses to variant peptides seen with T cell lines specific to KTFPPTEPK361-369 and QRNAPRITF9-17 (Figure S5).

  • Ex vivo culture of primary human fallopian tube epithelial cells.

  • Ex vivo surface and mechanical properties of coated orthodontic archwires.

  • Ex vivo evaluation of four final irrigation protocols on the removal of hard-tissue debris from the mesial root canal system of mandibular first molars.

  • Ex vivo assessment of irrigant penetration and renewal during the final irrigation regimen.

  • Ex vivo assessment of irrigant penetration and renewal during the cleaning and shaping of root canals: a digital subtraction radiographic study.

  • Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood.

  • Ex vivo, in vitro and in silico methods for oral drug toxicity and transport studies are available, as presented above and also sum- marized in Table 3.

  • Ex vivo accuracy of three electronic apex locators: Root ZX, Elements Diagnostic Unit and Apex Locator and ProPex.


More Definitions of Ex vivo

Ex vivo means a biological process or reaction taking place outside of a living cell or organism;
Ex vivo specifically means where the cells or tissue are removed from a healthy donor (in the case of allogeneic therapy) or the patient (in the case of autologous therapy), modified ex vivo and then, implanted, transplanted, infused, or transferred into the patient. For purposes of clarity, specifically excluded from these Fields of Use are the following:
Ex vivo delivery shall mean the introduction, outside of the body of a human, of such compositions into a cell, tissue, organoid, or organ, followed by the administration of cell, tissue, organoid, or organ which contains such introduced compositions into the body of the same (autologous) or different (allogeneic) human, without limitation as to the formulation, anatomic site, or route of administration or the use of encapsulation or other devices for such administration, and (ii) "In Vivo" delivery shall mean the introduction of such compositions into an individual, without limitation as to the formulation, anatomic site, or route of administration or the use of encapsulation or other devices for such administration. "Licensed Product(s)" shall mean [*] Licensed Products and [*] Licensed Products. "[*] Licensed Product" shall mean [*] of a Designated Protein, the making, using, selling, offering for sale or import of which is covered by a claim in the Patent Rights. "[*] Licensed Product" shall mean [*], the making, using, selling, offering for sale or import of which is covered by a claim in the Patent Rights. For clarity, the term "Licensed Product(s)" does not include a composition that includes a protein that is covered by, or that was made by a process covered by, a claim in the Patent Rights, if that protein is not a Designated Protein.
Ex vivo means that cells are extracted from a patient, corrected or otherwise modified by Gene Therapy, and transplanted or dosed
Ex vivo means outside of a living animal.

Related to Ex vivo

  • Pump spray means a packaging system in which the product ingredients within the container are not under pressure and in which the product is expelled only while a pumping action is applied to a button, trigger or other actuator.

  • Anaerobic digestion ’ means a controlled process involving microbial decomposition of organic matter in the absence of oxygen ;

  • Anaerobic digester means a liquid manure storage area that is constructed with the intent to capture and combust gas emissions resulting from the digestion of waste by microbes in anaerobic conditions. An anaerobic digester is a LMSA and is required to comply with all requirements applicable to LMSAs. Requirements specific to anaerobic digesters will be noted when applicable.

  • Spray buff product means a product designed to restore a worn floor finish in conjunction with a floor buffing machine and special pad.

  • COVID-19 symptoms means fever of 100.4 degrees Fahrenheit or higher, chills, cough, shortness of breath or difficulty breathing, fatigue, muscle or body aches, headache, new loss of taste or smell, sore throat, congestion or runny nose, nausea or vomiting, or diarrhea, unless a licensed health care professional determines the person’s symptoms were caused by a known condition other than COVID-19.

  • Opioid antagonist means a drug that binds to opioid

  • HEPA filter means high-efficiency particulate air filters that are rated to achieve a minimum initial particle-removal efficiency of 99.97 per cent using ASTM F 1471– 93 or equivalent standard;

  • Anabolic steroid means any drug or hormonal substance, chemically and pharmacologically related

  • haemophilia means an inheritable disease, usually affecting only male but transmitted by women to their male children, characterised by loss or impairment of the normal clotting ability of blood so that a minor would may result in fatal bleeding;

  • Nitrogen oxides means nitric oxide and nitrogen dioxide, expressed as nitrogen dioxide (NO2);

  • Collaborative drug therapy management means participation by an authorized pharmacist and a physician in the management of drug therapy pursuant to a written community practice protocol or a written hospital practice protocol.

  • SFTR means Regulation (EU) 2015/2365 of the European Parliament and of the Council of 25 November 2015 on transparency of securities financing transactions and of reuse and amending Regulation (EU) No 648/2012;

  • Dental laboratory means a person, firm or corporation

  • Pyrolysis means the thermal degradation of a substance in the absence of any oxidising agent, which does not form part of the substance itself, to produce char and gas and/or liquid; and

  • Marijuana producer means a person who produces marijuana in this state.

  • Marijuana product means marijuana as defined in 50-32-101 and marijuana-infused products

  • Electrostatic spray means a method of applying a spray coating in which opposite electric charges are applied to the substrate and the coating. The coating is attracted to the substrate by the electrostatic potential between them.

  • MVA means Megavolt Ampere.

  • Cannabinoid means any of the chemical compounds that are the active constituents of marijuana.

  • Halogen means one of the chemical elements chlorine, bromine or iodine.

  • Cannabinoid edible means food or potable liquid into which a cannabinoid concentrate, cannabinoid extract or dried marijuana leaves or flowers have been incorporated.

  • Corrosion inhibitor means a substance capable of reducing the corrosivity of water toward metal plumbing materials, especially lead and copper, by forming a protective film on the interior surface of those materials.

  • Alcohol Screening Device (ASD) means a breath or saliva device, other than an Evidential Breath Testing Device (EBT), that is approved by the National Highway Traffic Safety Administration and placed on its Conforming Products List for such devices.

  • Medical marijuana concentrate means a specific subset of Medical Marijuana that was produced by extracting cannabinoids from Medical Marijuana. Categories of Medical Marijuana Concentrate include Water-Based Medical Marijuana Concentrate, Food-Based Medical Marijuana Concentrate and Solvent-Based Medical Marijuana Concentrate.

  • Diagnostic mammography means a method of screening that

  • Reference evapotranspiration or “ETo” means a standard measurement of environmental parameters which affect the water use of plants. ETo is given expressed in inches per day, month, or year as represented in Appendix C of these Guidelines, and is an estimate of the evapotranspiration of a large field of four to seven-inch tall, cool-season grass that is well watered. Reference evapotranspiration is used as the basis of determining the Maximum Applied Water Allowances.