Intention to treat definition

Intention to treat means a procedure in the conduct and analysis of randomized controlled trials. All patients allocated to a given arm of the treatment regimen are included in the analysis whether or not they received or completed the prescribed regimen. Failure to follow this step defeats the main purpose of random allocation and can invalidate the results.
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Intention to treat means that the analysis is based on the initial intentions to provide tuition, rather than whether or not pupils actually received tuition. Our analysis was not done on an ‘intention to treat’ basis: if a pupil was intended to receive tuition, but for some reason did not, they would be excluded from our analysis.
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Intention to treat means analysing all randomised patients for the most important outcome measures, and on the most important moments of effect measurement irrespective of non-compliance and co-interventions.
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Examples of Intention to treat in a sentence

  • Intention to treat analysis, compliance, drop-outs and how to deal with missing data in clinical research: a review.

  • Intention to treat analysis is related to methodological quality.

  • Intention to treat analysis in clinical trials when there are missing data.

  • Refractory status epilepticus in children: Intention to treat with continuous infusions of midazolam and pentobarbital.

  • Table 9: Universal effects - Intention to treat analysis OutcomeIntervention group n Mean(95% CI) H1: Children in classes implementing FRIENDS demonstrate measureable improvements in Key Stage 2 Maths and Reading combined scores (equal weighting) when compared to those children attending comparison classes.

  • Intention to treat analysis was used for the assessment of the disease or PFS and the comparison between various regimens was done using the Kaplan Maier curves.

  • Intention to treat (ITT) patient-survival of at least 5 years must be preferred to absolute survival for all end-stage liver disease (ESLD) patients, with or without HCC, because ITT analysis can capture the entire therapeutic process, including livertransplantation.

  • Two different analysis sets are defined: (Modified) Intention to treat setThis analysis set includes all subjects where the outcome can be calculated (more than two blood samples taken), even though the subject was not observed the full 18 weeks.

  • Intention to treat analysis Whilst Novartis maintains the infused population is most appropriate, acknowledging the strong views expressed by the evaluators, the resubmission adopts the ITT population in the base case analysis.

  • Intention to treat analysis versus per protocol analysis of trial data.

Related to Intention to treat

  • Business with which he is associated means any business of which a public servant or his relative is an officer, director, owner, partner, employee or is a holder of more than ten percent (10%) of the fair market value or from which he or his relative derives more than Two Thousand Five Hundred Dollars ($2,500.00) in annual income or over which such public servant or his relative exercises control.

  • Election to Exercise shall have the meaning attributed thereto in Subsection 2.2(d).

  • Undue influence means exploiting a position of power in relation to the consumer so as to apply pressure, even without using or threatening to use physical force, in a way which significantly limits the consumer's ability to make an informed decision;

  • MiFID means Directive 2004/39/EC on markets in financial instruments amending Council Directives 85/611/EEC and 93/6/EEC and Directive 2000/12/EC of the European Parliament and of the Council and repealing Council Directive 93/22/EEC;