Matrix effect definition

Matrix effect means any change in the method detection limit or practical quantitation limit for a given analyte as a result of the presence of other constituents - either of natural origin or introduced by humans as a result of a release or spill - that are present in the sample of water or soil-pore gas being analyzed.
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Matrix effect means an influence of one or more components from the sample matrix on the measurement of the analyte concentration or mass. Matrix effects may be observed as increased or decreased detec- tor responses, compared with those produced by simple solvent solu- tions of the analyte.
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Matrix effect means the difference in analytical response between a standard dissolved in the solvent and a matrix- matched standard either without a correction using an internal standard or with correction using an internal standard;
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Examples of Matrix effect in a sentence

  • Figure 5 Matrix effect and recovery parameters for DP1-4 targets and respective 13C labelled internal standard in cocoa powder, baking chocolate, whole milk powder, whey protein, corn starch, soy flour and wheat flour.

  • Matrix effect and extraction efficiency data for the detection of POPE and EtG in UC.

  • Matrix effect studied by comparing the response of extracted samples spiked before extraction with response of the blank matrix sample to which analyte has been added at the same nominal concentration just before injection.

  • The Court also does not consider either of the parties’ requests for judicial notice because the documents at issue are not necessary for the purposes of this Order.263 In their Reply, Defendants argue for the first time that a First Amendment claim cannot be based on27 a theory of deliberate indifference.

  • To the extent any provision of this Plan or action by the Committee would fail to be in compliance with such conditions, they may be deemed null and void by the Committee.Amendment and Termination.

  • Matrix effect (ME) profiles obtained by post-column infusion of fenbendazole (m/z 300 → m/z 268) in 4 extracts obtained using different clean-up sorbents; the veterinary drug analytes elute between 0.7 and 10 min.‌ −effect (ME < 60%) was observed for all extracts between 0.4 and1.0 min, which explains the poor results for the 3 early-eluting analytes (desacetyl cephapirin, florfenicol amine and 2-thiouracil), as also noted previously [7,19].

  • Matrix effect; the concentration is an estimate due to matrix effect.

  • Matrix effect is another common problem associated with analysis of a complex biological sample with mass spectrometry.

  • Matrix effect was within ± 20% at both QC levels for all analytes, except for HYDROXY which was suppressed by 34.4 ± 7.4% at QC Low and by 32.6 ± 4.6% at QC High.

  • Matrix effect is the effect on Bioanalytical method caused by all other components of the sample except the specific compound to be quantified.


More Definitions of Matrix effect

Matrix effect means any increase in the Method Detection Limit or Peak Quantitation Limit for a given constituent as a result of the presence of other constituents, either of natural origin or introduced through a release, that are present in the sample of water or soil-pore gas being
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Related to Matrix effect

  • Nonstochastic effect means a health effect, the severity of which varies with the dose and for which a threshold is believed to exist. Radiation-induced cataract formation is an example of a nonstochastic effect. For purposes of these regulations, "deterministic effect" is an equivalent term.

  • Impact means any effect caused by a proposed activity on the environment including human health and safety, flora, fauna, soil, air, water, climate, landscape and historical monuments or other physical structures or the interaction among these factors; it also includes effects on cultural heritage or socio-economic conditions resulting from alterations to those factors;

  • Amendment No. 1 Effective Date has the meaning specified in Amendment No. 1.

  • Additional Effective Date means the date the Additional Registration Statement is declared effective by the SEC.