VEGF Trap definition

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Examples of VEGF Trap in a sentence

  • In addition, spending on Exubera and Apidra in the first quarter of 2003 was partly offset by higher development costs related to VEGF Trap (developed in cooperation with Regeneron Pharmaceuticals, Inc.), Lantus and Lovenox in the first quarter of 2004.

  • The companies will evaluate the VEGF Trap in a variety of cancer types, both in single-agent studies and in combination with chemotherapy.

  • The VEGF Trap has a relatively long half-life of approximately two weeks.

  • Regeneron and sanofi-aventis plan to meet with the U.S. Food and Drug Administration (FDA) to discuss these Phase 2 results and determine the next steps in the development program for the aflibercept (VEGF Trap).

  • About Aflibercept Aflibercept (VEGF Trap) is an investigational angiogenesis inhibitor with a unique mechanism of action.

  • In addition to ARCALYST® (rilonacept) Injection for Subcutaneous Use, which is approved for the treatment of a rare inflammatory condition, Regeneron has completed Phase 3 clinical trials of rilonacept for a new indication and of product candidates EYLEA™ (aflibercept injection; VEGF Trap Eye) in diseases of the eye and ZALTRAP® (aflibercept) (VEGF Trap) in a cancer indication.

  • About aflibercept (VEGF Trap) in Oncology The VEGF Trap is a fully human soluble VEGF receptor fusion protein with a unique mechanism of action.

  • In connection with this agreement, sanofi-aventis will make a one-time payment to Regeneron of $25 million, of which 50% is repayable to sanofi-aventis following commercialization of the VEGF Trap.

  • Each Supply Agreement shall include as an annex thereto, a customary quality agreement containing terms and conditions regarding quality assurance and Good Practices with respect to the manufacture of VEGF Trap Products or Formulated Bulk VEGF Products.

  • VEGF Trap is an innovative fusion protein of VEGF binding segments from the human VEGF receptors with a human antibody backbone.

Related to VEGF Trap

  • Conventional filtration treatment means a series of processes including coagulation, flocculation, sedimentation, and filtration resulting in substantial particulate removal.

  • Anabolic steroid means any drug or hormonal substance, chemically and pharmacologically related

  • Receptor means enclosed spaces, conduits, protected groundwater sources, drinking and non-drinking water wells, surface water bodies, and public water systems which when impacted by chemicals of concern may result in exposure to humans and aquatic life, explosive conditions or other adverse effects on health, safety and the environment as specified in these rules.

  • HEPA filter means a high efficiency particulate absolute air filter capable of trapping and retaining 99.97 percent of fibers greater than 0.3 micrometers in mass median aerodynamic diameter equivalent.

  • haemophilia means an inheritable disease, usually affecting only male but transmitted by women to their male children, characterised by loss or impairment of the normal clotting ability of blood so that a minor would may result in fatal bleeding;

  • Cannabis cultivator means any licensed person or entity that grows, cultivates, or produces cannabis in this State, and sells, and may transport, this cannabis to other cannabis cultivators, or usable cannabis to cannabis manufacturers, cannabis wholesalers, or cannabis retailers, but not to consumers.

  • Opioid means a drug that produces an agonist effect on opioid receptors and is indicated or used for the treatment of pain.

  • HBV means hepatitis B virus.

  • SFTR means Regulation (EU) 2015/2365 of the European Parliament and of the Council of 25 November 2015 on transparency of securities financing transactions and of reuse and amending Regulation (EU) No 648/2012;

  • Opioid antagonist means a drug that binds to opioid

  • Virus means any thing or device (including any software, code, file or programme) which may: prevent, impair or otherwise adversely affect the operation of any computer software, hardware or network, any telecommunications service, equipment or network or any other service or device; prevent, impair or otherwise adversely affect access to or the operation of any programme or data, including the reliability of any programme or data (whether by re-arranging, altering or erasing the programme or data in whole or part or otherwise); or adversely affect the user experience, including worms, trojan horses, viruses and other similar things or devices.

  • Opioid antidote means any drug, regardless of dosage amount or method of administration, which has been approved by the United States Food and Drug Administration (FDA) for the treatment of an opioid overdose. “Opioid antidote” includes, but is not limited to, naloxone hydrochloride, in any dosage amount, which is administered through nasal spray or any other FDA-approved means or methods.

  • Disinfection profile means a summary of Giardia lamblia inactivation through the treatment plant.

  • coronavirus means severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2);

  • Membrane filtration means a pressure or vacuum driven separation process in which particulate matter larger than 1 micrometer is rejected by an engineered barrier, primarily through a size-exclusion mechanism, and which has a measurable removal efficiency of a target organism that can be verified through the application of a direct integrity test. This definition includes the common membrane technologies of microfiltration, ultrafiltration, nanofiltration, and reverse osmosis.

  • Antibody means a molecule or a gene encoding such a molecule comprising or containing one or more immunoglobulin variable domains or parts of such domains or any existing or future fragments, variants, modifications or derivatives thereof.

  • Vaccine means a specially prepared antigen which, upon administration to a person, will result in immunity and, specifically for the purposes of this rule, shall mean influenza and pneumococcal vaccines.

  • Polystyrene foam means blown polystyrene and expanded and

  • Parenteral means a method of drug delivery injected into body tissues but not via the gastrointestinal tract.

  • Radiopharmaceutical means any drug that exhibits spontaneous disintegration of unstable nuclei with the emission of nuclear particles or photons and includes any non-radioactive reagent kit or radionuclide generator that is intended to be used in the preparation of any such substance, but does not include drugs such as carbon-containing compounds or potassium-containing salts that include trace quantities of naturally occurring radionuclides. The term also includes any biological product that is labeled with a radionuclide or intended solely to be labeled with a radionuclide.

  • Cannabinoid means any of the chemical compounds that are the active constituents of marijuana.

  • Field-flattening filter means a filter used to homogenize the absorbed dose rate over the radiation field.

  • HIV means human immunodeficiency virus.

  • Grab sample means an individual sample collected in less than 15 minutes in conjunction with an instantaneous flow measurement.

  • Radiopharmaceutical service means, but is not limited to, the procurement, storage, handling preparation, labeling, quality assurance testing, dispensing, delivery, recordkeeping, and disposal of radiopharmaceuticals and other drugs.

  • Marihuana-infused product means a topical formulation, tincture, beverage, edible substance, or similar product containing marihuana and other ingredients and that is intended for human consumption.