Immune Response Determined by Intracellular Cytokine Staining Assay Sample Clauses

Immune Response Determined by Intracellular Cytokine Staining Assay. Dimethyl sulfoxide (DMSO)-subtracted cytokine response, as well as DMSO cytokine response (to better understand the distribution of background noise in the assay) will be used to summarise percentage CD4+ and CD8+ T cell response by treatment group and stimulation antigen. Summaries will include the assessment of response at all pre- and post-vaccination immunogenicity time points, as well as change from pre-vaccination to each post-vaccination time point, by treatment group. The number (percentage) of participants designated as a responder according to the SAP will be summarised at each time point for ICS, and across all available time points compared to baseline cytokine expression, for all vaccinated participants by treatment group.
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