Incidence, Duration, and Risk Factors of ADL in Endemic Populations Sample Clauses

Incidence, Duration, and Risk Factors of ADL in Endemic Populations. The incidence of ADL varies somewhat by region, yet consistent risk factors include presence of chronic filariasis [39-44] and increasing age [39-45]. Other less consistent risk factors are gender [39, 42, 43, 45] (contrasting results of male vs. female), lymphedema grade [9, 46], as well as the rainy season [11, 43]. In two studies, microfilaremia was found to be a statistically significant effect modifier [11, 41]. In one study it modified the relationship between ADL and chronic filariasis [11], while in the other it modified the relationship between ADL and age [41]. The mean duration of ADL episodes does not appear to exceed 7 days, while most studies averaged around 4-6 days. Hydrocele pathology was positively associated with duration of episode in two studies [39, 40]. The mean number of episodes (typically over a 1 year period) was relatively low, between 1 and 2. Risk factors for number of episodes include female gender [39, 40], chronic disease [39], season [40], and lymphedema severity [47].
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