Measuring Fatigue in Rheumatoid Arthritis Sample Clauses

Measuring Fatigue in Rheumatoid Arthritis. There are a number of multidimensional instruments available that measure fatigue but no consensus on the most appropriate instrument to use in RA. Most multidimensional instruments were designed for use in other chronic illnesses but have been applied to RA. Two of these measures have been validated in RA. The first of which is the multidimensional assessment of fatigue (MAF) [Xxxxx et al. 1993]. This is a 16 item scale with 4 domains; severity, distress, degree of interference of daily living and timing. The other validated instrument is the functional assessment of chronic illness therapy –fatigue scale (FACIT-F) [Xxxxx et al. 2005], which has 13 questions with 4 domains; general, physical, mental fatigue and vigour. Other multidimensional instruments that have been used include an instrument developed for cancer (the MFSI) [Xxxxx et al. 1998], the Chalder fatigue scale [Xxxxxxx et al. 1993], and the fatigue symptom inventory [Xxxx et al. 1998]. Generic health measures such as the SF-36 which can be used in any disease also have subscales (energy and vitality) that measure fatigue, though these are less specific. There are no reported head to head comparisons of all these instruments. However, Xxxxx [2004] has shown that in RA the VAS performs well in comparison to the MAF, energy and vitality scale of the SF-36 and brief fatigue inventory, in terms of sensitivity to change and correlation with clinical variables. These patients had substantially worse quality of life. Clearly further work focusing specifically on fatigue in RA is needed, specifically, to determine the most appropriate instrument.
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