Melatonin Efficacy in Treating Metabolic Syndrome Sample Clauses

Melatonin Efficacy in Treating Metabolic Syndrome. The effects of melatonin on improving signs and symptoms of metabolic syndrome, as well as the overall syndrome itself, have been shown in various animal studies. (Xxxxxxxxx, Xxxxx, & Xxxxxxxxx, 2003; Xxxxx, et al., 2000). Both animal and human studies have documented melatonin’s hypotensive effect, antioxidative potential, and improvement in lipid profile and reduction of pharmaceutical agent toxicity. (Xxxxxxx, et al., 2011; Xxxxxx, Xxx, Xxxxx, & Xxxx, 2002). Xxxxxxx et al. conducted a study in 2011 to assess melatonin efficacy in treating metabolic syndrome and found that melatonin significantly reduced the patients’ BMI, systolic and diastolic blood pressure (SBP, DBP) and thiobarbituric acid reactive substrates after one-month and two-month administration. They also reported that melatonin significantly lowered SBP comparing the two visits at the end of the first and second month and further proposed that prolonged administration of melatonin may yield a better outcome. (Xxxxxxx, et al., 2011). An eight-week, double-blind, randomized, placebo-controlled, parallel-group clinical trial done in 2014 examined the metabolic effects of melatonin among second-generation antipsychotics (SGA) patients, a group of people who tend to have metabolic disturbances. The results supported the therapeutic role of melatonin in preventing patients from experiencing SGA metabolic effects. (Xxxx-Xxxx, et al., 2014). In a review paper by Xxxxxxxxxxxx, du Toit, and Xxxxxxx et al, the dosage level of melatonin was proposed to be a particular challenge since both low and high doses seemed to be effective in experimental animals. The authors suggested that the therapeutic characteristics of melatonin need further investigation considering its potential benefits on preventing or reversing harmful effects of obesity and related metabolic disorder. (Nduhirabandi, du Toit, & Xxxxxxx, 2012). In addition, Xxxxxxxxxx et al. recommended more studies to further prove the efficacy of melatonin with dosage level increases as well as longer duration of melatonin treatment. (Xxxxxxxxxx, et al., 2013).
AutoNDA by SimpleDocs

Related to Melatonin Efficacy in Treating Metabolic Syndrome

  • Hepatitis B Vaccine Where the Hospital identifies high risk areas where employees are exposed to Hepatitis B, the Hospital will provide, at no cost to the employees, a Hepatitis B vaccine.

  • Human Leukocyte Antigen Testing This plan covers human leukocyte antigen testing for A, B, and DR antigens once per member per lifetime to establish a member’s bone marrow transplantation donor suitability in accordance with R.I. General Law §27-20-36. The testing must be performed in a facility that is: • accredited by the American Association of Blood Banks or its successors; and • licensed under the Clinical Laboratory Improvement Act as it may be amended from time to time. At the time of testing, the person being tested must complete and sign an informed consent form that also authorizes the results of the test to be used for participation in the National Marrow Donor program.

  • Influenza Vaccine Upon recommendation of the Medical Officer of Health, all employees shall be required, on an annual basis to be vaccinated and or to take antiviral medication for influenza. If the costs of such medication are not covered by some other sources, the Employer will pay the cost for such medication. If the employee fails to take the required medication, she may be placed on an unpaid leave of absence during any influenza outbreak in the home until such time as the employee has been cleared by the public health or the Employer to return to the work environment. The only exception to this would be employees for whom taking the medication will result in the employee being physically ill to the extent that she cannot attend work. Upon written direction from the employee’s physician of such medical condition in consultation with the Employer’s physician, (if requested), the employee will be permitted to access their sick bank, if any, during any outbreak period. If there is a dispute between the physicians, the employee will be placed on unpaid leave. If the employee gets sick as a reaction to the drug and applies for WSIB the Employer will not oppose the application. If an employee is pregnant and her physician believes the pregnancy could be in jeopardy as a result of the influenza inoculation and/or the antiviral medication she shall be eligible for sick leave in circumstances where she is not allowed to attend at work as a result of an outbreak. This clause shall be interpreted in a manner consistent with the Ontario Human Rights Code.

  • Nepotism No employee shall be directly supervised by a member of his/her immediate family. “

  • Musculoskeletal Injury Prevention and Control The hospital in consultation with the Joint Health and Safety Committee (JHSC) shall develop, establish and put into effect, musculoskeletal prevention and control measures, procedures, practices and training for the health and safety of employees.

  • COVID-19 Vaccine Passports Pursuant to Texas Health and Safety Code, Section 161.0085(c), Contractor certifies that it does not require its customers to provide any documentation certifying the customer’s COVID-19 vaccination or post-transmission recovery on entry to, to gain access to, or to receive service from the Contractor’s business. Contractor acknowledges that such a vaccine or recovery requirement would make Contractor ineligible for a state-funded contract.

  • Random Drug Testing All employees covered by this Agreement shall be subject to random drug testing in accordance with Appendix D.

  • RE-WEIGHING PRODUCT Deliveries are subject to re- weighing at the point of destination by the Authorized User. If shrinkage occurs which exceeds that normally allowable in the trade, the Authorized User shall have the option to require delivery of the difference in quantity or to reduce the payment accordingly. Such option shall be exercised in writing by the Authorized User.

  • Infectious Diseases The Employer and the Union desire to arrest the spread of infectious diseases in the nursing home. To achieve this objective, the Joint Health and Safety Committee may review and offer input into infection control programs and protocols including surveillance, outbreak control, isolation, precautions, worker education and training, and personal protective equipment. The Employer will provide training and ongoing education in communicable disease recognition, use of personal protective equipment, decontamination of equipment, and disposal of hazardous waste.

  • Preceptor A per diem Registered Nurse 2 may serve as a preceptor after successfully completing a preceptor workshop or equivalent documented training and agreeing to and being appointed to be specifically responsible for planning, organizing, and evaluating the new skill development of one or more RNs as appropriate enrolled in a defined orientation program, the parameters of which have been set forth in writing by the Employer. This includes teaching, clinical supervision, role modeling, feedback, evaluation (verbal and written) and follow up of the new or transferring employee. The per diem RN 2 preceptor is eligible to receive preceptor premium pay when actually engaged in preceptor role responsibilities with/on behalf of the orienting RN. A per diem RN 2 substituting for the original preceptor during a period of absence and who has been designated to carry out the preceptor's complete responsibility (including following and/or adjusting the plan to meet learning needs and providing oral and written evaluation input) will receive preceptor pay. A preceptor may be assigned to a student when it is determined by the Employer that the employee has completed the required preceptor training or has agreed to and been appointed a preceptor. The employee is specifically responsible for planning, organizing, and evaluating the new skill development of the student as appropriately enrolled in a defined program, the parameters of which have been set forth in writing by the Employer. This includes teaching, clinical supervision, role modeling, feedback, evaluation (verbal and written) and follow up of the student.

Draft better contracts in just 5 minutes Get the weekly Law Insider newsletter packed with expert videos, webinars, ebooks, and more!