PNU-120596 Sample Clauses

PNU-120596. PNU-120596 [Tocris] is a positive allosteric modulator at α7 nAChRs (Xxxxx, Xxxxx et al. 2005; Gronlien, Hakerud et al. 2007). PNU-120596 was dissolved in DMSO at a stock concentration of 20 mM and applied at 1 μM. The preparation was exposed to a final concentration of 0.05% DMSO in aCSF. Control experiments were performed with only DMSO, and no physiological effects were observed at this concentration.
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