Retina Sample Clauses

Retina. The retina displays the expression of mGluR6 that is not found anywhere else in the CNS. In the retina mGluR6 expression was limited to the outer plexiform layer. mGluR 4, 7, and 8 exhibited discrete, punctate immunolabeling that was found exclusively in the inner plexiform layer (IPL). mGluR4 immunostaining was most abundant in IPL sublamina 1, mGluR7 immunoreactivity was organized in four bands, corresponding to sublaminae 1-4, and mGluR8 was localized in two broad bands, one each in the OFF and ON layers of the IPL. Localization of mGluR8 selectively on the OFF cholinergic amacrine plexus and not on the ONcholinergic processes implies that this receptor could play a role in directional-selective processing of light stimuli (Quiraishi et al., 2007). Group-III mGluR immunolabeling showed little colocalization between the different subtypes and also did not co-express significantly with the vesicular glutamate transporter VGLUT1, localizing instead adjacent to bipolar cell ribbons (Quiraishi et al., 2007). The pattern of expression that group III mGluR exhibit in the retina indicates that they have of distinct functions in the retina: each receptor modulating a specific group of cells. In the case of mGluR8 the asymmetric distribution in the ON and OFF layers of the IPL suggests discrete mechanisms in modulation neurotransmission that results from the presence and absencof light (Xxxxxxxx et al., 2007). In fact , APB stimulation of group-III mGluRs was shown to depress OFF-bipolar cell output (Xxxxxxxxxx and Xxxxxxxxx, 2001; Xxxxx et al., 2002).
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Retina. Primary sources of vision loss are due to loss of: • Photoreceptors: age-related macular degeneration, retinitis pigmentosa and retinal detachment. • Retinal ganglion degeneration: glaucoma

Related to Retina

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  • Testing Landlord shall have the right to conduct annual tests of the Premises to determine whether any contamination of the Premises or the Project has occurred as a result of Tenant’s use. Tenant shall be required to pay the cost of such annual test of the Premises; provided, however, that if Tenant conducts its own tests of the Premises using third party contractors and test procedures acceptable to Landlord which tests are certified to Landlord, Landlord shall accept such tests in lieu of the annual tests to be paid for by Tenant. In addition, at any time, and from time to time, prior to the expiration or earlier termination of the Term, Landlord shall have the right to conduct appropriate tests of the Premises and the Project to determine if contamination has occurred as a result of Tenant’s use of the Premises. In connection with such testing, upon the request of Landlord, Tenant shall deliver to Landlord or its consultant such non-proprietary information concerning the use of Hazardous Materials in or about the Premises by Tenant or any Tenant Party. If contamination has occurred for which Tenant is liable under this Section 30, Tenant shall pay all costs to conduct such tests. If no such contamination is found, Landlord shall pay the costs of such tests (which shall not constitute an Operating Expense). Landlord shall provide Tenant with a copy of all third party, non-confidential reports and tests of the Premises made by or on behalf of Landlord during the Term without representation or warranty and subject to a confidentiality agreement. Tenant shall, at its sole cost and expense, promptly and satisfactorily remediate any environmental conditions identified by such testing in accordance with all Environmental Requirements. Landlord’s receipt of or satisfaction with any environmental assessment in no way waives any rights which Landlord may have against Tenant.

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  • Protocol No action to coerce or censor or penalize any negotiation participant shall be made or implied by any other member as a result of participation in the negotiation process.

  • Technical Services Party B will provide technical services and training to Party A, taking advantage of Party B’s advanced network, website and multimedia technologies to improve Party A’s system integration. Such technical services shall include:

  • Manufacturing and Marketing Rights The Company has not granted rights to manufacture, produce, assemble, license, market, or sell its products to any other person and is not bound by any agreement that affects the Company's exclusive right to develop, manufacture, assemble, distribute, market, or sell its products.

  • ANALYSIS AND MONITORING The Custodian shall (a) provide the Fund (or its duly-authorized investment manager or investment adviser) with an analysis of the custody risks associated with maintaining assets with the Eligible Securities Depositories set forth on Schedule B hereto in accordance with section (a)(1)(i)(A) of Rule 17f-7, and (b) monitor such risks on a continuing basis, and promptly notify the Fund (or its duly-authorized investment manager or investment adviser) of any material change in such risks, in accordance with section (a)(1)(i)(B) of Rule 17f-7.

  • Acceptance Testing At the time of installation of a LIS trunk group, and at no additional charge, acceptance tests will be performed to ensure that the service is operational and meets the applicable technical parameters.

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