Solubilizing ability of NADES Sample Clauses

Solubilizing ability of NADES. Considering the different polarities of the NADES, it is possible that they act as an alternative media to water in organisms, dissolving non water-soluble metabolites or macromolecules. In particular, many plant secondary metabolites are not soluble in water at all, but are synthesized, stored, and transported in plants. A model experiment was carried out to explore the solubilizing capacity of NADES. For this, the solubility of the non-water soluble or poorly water soluble natural products rutin, quercetin, cinnamic acid, carthamin, taxol, ginkgolide B, and 1,8-dihydroxyanthraquinone in LGH, GCH, PCH, and xylitol-choline chloride-water (XoCH) was measured and compared with their solubility in water (Table 4). The results indicate that the solubility of most tested compounds was highest in PCH, which is reasonable, considering that PCH is the least polar. It is noteworthy that the solubility of these compounds increased in NADES by 18 to 460,000 times compared to water. As a further step, the influence of the water content on the solubilizing capacity of GCH was investigated (Fig. 5). In this case, addition of a small amount of water in GCH can increase its solubilizing capacity and the optimum water content depended on the compound. For example, rutin showed the highest solubility in GCH with 5% (v/v) water and carthamin was best soluble in GCH with 10% (v/v) water. These results show that water is an important factor in optimizing natural NADES. The solubility of quercetin and carthamin was higher in XoCH than in PCH. Taxol and 1,8-dihydroxyanthraquinone have the highest solubility in LGH, although LGH is the most polar of the tested NADES. In order to gain more insight into the solubilizing mechanism of NADES, high-resolution magic angle spinning (HR-MAS) NMR was selected to analyze a saturated solution of quercetin in XoCH. Obvious cross peaks between quercetin and XoCH were observed in the HR-MAS-NOESY spectrum (Fig. 6) indicating that the interaction forces, might result from hydrogen bonding between NADES molecules and solutes, providing an explanation of the high solubilizing capacity of NADES. In addition, the solubility of compounds in NADES affected a lot by temperature. Increasing temperature from 40 to 50 oC, the solubility of quercetin increased to 2.3 times higher in GCH and 1.65 times higher in PCH (Table 5). Table 4. Solubility of small molecules (m mole) including rutin, quercetin, cinnamic acid, carthamin, 1,8-dihydroxy-anthraquinone, t...
AutoNDA by SimpleDocs

Related to Solubilizing ability of NADES

  • STABILITY OF AGREEMENT Section 1 No amendment, alteration or variation of the terms or provisions of this Agreement shall bind the parties hereto unless made and executed in writing.

  • Technical Feasibility of String While ICANN has encouraged and will continue to encourage universal acceptance of all top-­‐level domain strings across the Internet, certain top-­‐level domain strings may encounter difficulty in acceptance by ISPs and webhosters and/or validation by web applications. Registry Operator shall be responsible for ensuring to its satisfaction the technical feasibility of the TLD string prior to entering into this Agreement.

  • VISIBILITY OF FUNDING FROM THE OFFICIAL DEVELOPMENT ASSISTANCE Unless the SAIDC requests or agrees otherwise, any communication or publication made by the Final Beneficiary that relates to the action, including at conferences, seminars or in any information or promotional materials (such as brochures, leaflets, posters, presentations in electronic form, etc.), including tangible assets acquired from the project must: (a) indicate that the action has received funding from the Official Development Assistance, SlovakAid and (b) display the SlovakAid logo. When displayed in association with another logo, the SlovakAid logo must have appropriate prominence. The obligation to display the SlovakAid logo does not confer on the Final Beneficiary a right of exclusive use. The Final Beneficiary may not appropriate the SlovakAid logo or any similar trademark or logo, either by registration or by any other means. For the purposes of the first, second and third subparagraphs and under the conditions specified therein, the Final Beneficiary may use the SlovakAid logo without first obtaining permission from the SAIDC.

  • Applicability of ¶ 2501 Local Church acknowledges and agrees that pursuant to ¶ 2501 of the Discipline, the Local Church holds all its property, real and personal, tangible and intangible, in trust for the benefit of The United Methodist Church, including the Real Property and Personal Property, and the Local Church will not take any actions that are inconsistent therewith or opposing or negating the same.

  • Applicability of Data Privacy Protections In the event that Personal Information will be Processed by Supplier in connection with the performance under this Agreement (including any SOW), then and only then shall the provisions of this Section ‘Data Protection and Privacy’ be applicable. For the avoidance of doubt, the data security requirements contained in section ‘Information Security’ shall apply regardless of whether Personal Information is Processed under this Agreement or any SOW. All Personal Information obtained from or on behalf of DXC or in connection with performance pursuant to this Agreement shall be Processed and protected pursuant to this Section ‘Data Protection and Privacy’, the Section ‘Information Security’ and any other Sections of this Agreement that address Personal Information.

  • Unavailability of Services You understand and agree that the Services may at times be temporarily unavailable due to system maintenance or technical difficulties. In the event any of the services included in our Mobile Banking Services are unavailable, you acknowledge that you can deposit an original check at our branches or through ATM that accepts your deposit, or by mail.

  • Accessibility of Web-Based Information and Applications For State Agency Authorized User Acquisitions: Any web-based information and applications development, or programming delivered pursuant to the contract or procurement, will comply with New York State Enterprise IT Policy NYS-P08-005, Accessibility of Web-Based Information and Applications as follows: Any web-based information and applications development, or programming delivered pursuant to the contract or procurement, will comply with New York State Enterprise IT Policy NYS-P08- 005, Accessibility of Web-Based Information and Applications as such policy may be amended, modified or superseded, which requires that state agency web-based information and applications are accessible to persons with disabilities. Web-based information and applications must conform to New York State Enterprise IT Policy NYS-P08-005 as determined by quality assurance testing. Such quality assurance testing will be conducted by the State Agency Authorized User and the results of such testing must be satisfactory to the Authorized User before web-based information and applications will be considered a qualified deliverable under the contract or procurement.

  • Termination for Unavailability of Funds In the event of reduction, suspension, discontinuance or other unavailability of funds, CITY unilaterally may take appropriate action(s) including, but not limited to, immediately canceling or reducing existing service authorization, stopping or reducing further referrals of individuals, and/or reducing the maximum dollar amount of this AGREEMENT. CITY shall give GRANTEE no less than sixty (60) business days’ advance written notice of the action(s) CITY intends to take as a result of the unavailability of funds. CITY shall not be liable for start-up costs, or lost profits in the event of early termination.

  • AVAILABILITY OF AGREEMENT The employer must ensure that copies of this Agreement and the NES are available to all employees to whom they apply, such as on a notice board which is conveniently located at or near the workplace or through electronic means, whichever makes them more accessible. PART 2 - ENGAGEMENT

  • SURVIVABILITY OF OBLIGATIONS All provisions of the Contract that impose continuing obligations on the parties, including but not limited to the warranty, indemnity, and confidentiality obligations of the parties, shall survive the expiration or termination of the Contract.

Time is Money Join Law Insider Premium to draft better contracts faster.