Ardea Biosciences, Inc./De Sample Contracts

RECITALS
Termination Agreement • March 31st, 2003 • Intrabiotics Pharmaceuticals Inc /De • Pharmaceutical preparations • California
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LEASE BY AND BETWEEN
Lease Agreement • January 27th, 2000 • Introbiotics Phamaceuticals Inc
8,500,000 Shares ARDEA BIOSCIENCES, INC. Common Stock ($0.001 par value per Share) UNDERWRITING AGREEMENT
Underwriting Agreement • February 6th, 2012 • Ardea Biosciences, Inc./De • Pharmaceutical preparations • New York
EXHIBIT 10.13 LOAN AND SECURITY AGREEMENT INTRABIOTICS PHARMACEUTICALS, INC. TABLE OF CONTENTS
Loan and Security Agreement • January 27th, 2000 • Introbiotics Phamaceuticals Inc
ARDEA BIOSCIENCES, INC. and , AS WARRANT AGENT FORM OF PREFERRED STOCK WARRANT AGREEMENT
Preferred Stock Warrant Agreement • December 23rd, 2011 • Ardea Biosciences, Inc./De • Pharmaceutical preparations • New York

PREFERRED STOCK WARRANT AGREEMENT (this “Agreement”), dated as of between ARDEA BIOSCIENCES, INC., a Delaware corporation (the “Company”) and , a [corporation] [national banking association] organized and existing under the laws of and having a corporate trust office in , as warrant agent (the “Warrant Agent”).

ARDEA BIOSCIENCES, INC. and , AS WARRANT AGENT FORM OF COMMON STOCK WARRANT AGREEMENT
Common Stock Warrant Agreement • December 23rd, 2011 • Ardea Biosciences, Inc./De • Pharmaceutical preparations • New York

COMMON STOCK WARRANT AGREEMENT (this “Agreement”), dated as of between ARDEA BIOSCIENCES, INC., a Delaware corporation (the “Company”) and, a [corporation] [national banking association] organized and existing under the laws of and having a corporate trust office in , as warrant agent (the “Warrant Agent”).

SHORELINE TECHNOLOGY PARK MOUNTAIN VIEW, CALIFORNIA OFFICE LEASE AGREEMENT
Office Lease Agreement • February 29th, 2000 • Intrabiotics Pharmaceuticals Inc /De • Pharmaceutical preparations • California
ARDEA BIOSCIENCES, INC. and , AS WARRANT AGENT FORM OF DEBT SECURITIES WARRANT AGREEMENT
Debt Securities Warrant Agreement • December 23rd, 2011 • Ardea Biosciences, Inc./De • Pharmaceutical preparations • New York

DEBT SECURITIES WARRANT AGREEMENT (this “Agreement”), dated as of between ARDEA BIOSCIENCES, INC., a Delaware corporation (the “Company”) and , a [corporation] [national banking association] organized and existing under the laws of and having a corporate trust office in , as warrant agent (the “Warrant Agent”).

RECITALS
Lease Termination Agreement • March 31st, 2003 • Intrabiotics Pharmaceuticals Inc /De • Pharmaceutical preparations
RECITALS
Indemnification Agreement • January 27th, 2000 • Introbiotics Phamaceuticals Inc • Delaware
THIRD AMENDMENT TO LICENSE AGREEMENT M940121 (MARKED)
License Agreement • January 27th, 2000 • Introbiotics Phamaceuticals Inc
EXHIBIT I Pursuant to Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, the undersigned hereby agree that only one statement containing the information required on Schedule 13G need be filed with respect to ownership by each of the...
Exhibit Agreement • July 3rd, 2002 • Intrabiotics Pharmaceuticals Inc /De • Pharmaceutical preparations

Pursuant to Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, the undersigned hereby agree that only one statement containing the information required on Schedule 13G need be filed with respect to ownership by each of the undersigned of shares of Common Stock of Intrabiotics Pharmaceuticals, Inc.

EQUIPMENT FINANCING AGREEMENT (Number 10782)
Equipment Financing Agreement • January 27th, 2000 • Introbiotics Phamaceuticals Inc • California
STOCK PURCHASE AGREEMENT
Stock Purchase Agreement • February 15th, 2002 • Intrabiotics Pharmaceuticals Inc /De • Pharmaceutical preparations • California

Please confirm that the foregoing correctly sets forth the agreement between us by signing in the space provided below for that purpose.

Common Stock
Equity Underwriting Agreement • March 17th, 2000 • Intrabiotics Pharmaceuticals Inc /De • Pharmaceutical preparations • Maryland
SECOND AMENDMENT TO LICENSE AGREEMENT M940121 (UNMARKED)
License Agreement • March 23rd, 2000 • Intrabiotics Pharmaceuticals Inc /De • Pharmaceutical preparations • California
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EXHIBIT 10.5 DEVELOPMENT SUPPLY AGREEMENT
Development Supply Agreement • March 23rd, 2000 • Intrabiotics Pharmaceuticals Inc /De • Pharmaceutical preparations • California
REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • December 18th, 2008 • Ardea Biosciences, Inc./De • Pharmaceutical preparations

This Registration Rights Agreement (this “Agreement”) is made and entered into as of December 17, 2008, by and among Ardea Biosciences, Inc., a Delaware corporation (the “Company”), and the several purchasers signatory hereto (each a “Purchaser” and collectively, the “Purchasers”).

OFFICE LEASE EMBARCADERO CORPORATE CENTER
Office Lease • March 31st, 2003 • Intrabiotics Pharmaceuticals Inc /De • Pharmaceutical preparations • California
ARDEA BIOSCIENCES, INC. ISSUER AND [TRUSTEE], TRUSTEE FORM OF SENIOR DEBT INDENTURE
Senior Debt Indenture • December 23rd, 2011 • Ardea Biosciences, Inc./De • Pharmaceutical preparations • New York

INDENTURE, dated as of , 20 , among ARDEA BIOSCIENCES, INC., a Delaware corporation (the “Company”), and [TRUSTEE], as trustee (the “Trustee”):

ARDEA BIOSCIENCES, INC. AND [TRUSTEE], TRUSTEE FORM OF SUBORDINATED DEBT INDENTURE
Subordinated Debt Indenture • December 23rd, 2011 • Ardea Biosciences, Inc./De • Pharmaceutical preparations • New York

INDENTURE, dated as of , 20 , among ARDEA BIOSCIENCES, INC., a Delaware corporation (the “Company”), and [TRUSTEE], as trustee (the “Trustee”):

June 1, 2001 John Fiddes [address]
Severance Agreement • August 14th, 2001 • Intrabiotics Pharmaceuticals Inc /De • Pharmaceutical preparations

This Letter Agreement (the “Letter Agreement”) is to inform you in advance that IntraBiotics Pharmaceuticals, Inc. (the “Company”) is restructuring its workforce at its facilities located at 2021 Stierlin Court, Mountain View, California and 1245 Terra Bella, Mountain View, California. This restructuring constitutes a “mass layoff” under the WARN Act.

3,000,000 Shares Common Stock ($0.001 Par Value) EQUITY UNDERWRITING AGREEMENT
Equity Underwriting Agreement • April 22nd, 2004 • Intrabiotics Pharmaceuticals Inc /De • Pharmaceutical preparations • New York

IntraBiotics Pharmaceuticals, Inc., a Delaware corporation (the “Company”), proposes to sell to the several underwriters (the “Underwriters”) named in Schedule I hereto for whom you are acting as representatives (the “Representatives”) an aggregate of 3,000,000 shares of the Company’s Common Stock, $0.001 par value per share (the “Firm Shares”). The respective amounts of the Firm Shares to be so purchased by the several Underwriters are set forth opposite their names in Schedule I hereto. The Company also proposes to sell at the Underwriters’ option an aggregate of up to 450,000 additional shares of the Company’s Common Stock (the “Option Shares”) as set forth below.

EXECUTIVE EMPLOYMENT AGREEMENT
Executive Employment Agreement • December 28th, 2006 • Ardea Biosciences, Inc./De • Pharmaceutical preparations • California

This Employment Agreement (the “Agreement”) is made and entered into effective as of December 21, 2006 (the “Effective Date”), by and between Intrabiotics Pharmaceuticals, Inc., (the “Company”), and Dr. Barry Quart (the “Executive”). The Company and the Executive are hereinafter collectively referred to as the “Parties”, and individually referred to as a “Party”.

REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • December 22nd, 2008 • Ardea Biosciences, Inc./De • Pharmaceutical preparations

This Registration Rights Agreement (this “Agreement”) is made and entered into as of December 17, 2008, by and among Ardea Biosciences, Inc., a Delaware corporation (the “Company”), and the several purchasers signatory hereto (each a “Purchaser” and collectively, the “Purchasers”).

RESEARCH AND TECHNOLOGY AGREEMENT
Research and Technology Agreement • May 11th, 2001 • Intrabiotics Pharmaceuticals Inc /De • Pharmaceutical preparations • Delaware

This Research and Technology Agreement (the “Agreement”) is made effective as of January 24, 2001 (the “Effective Date”) between INTRABIOTICS PHARMACEUTICALS, INC., a Delaware corporation, having its principal place of business in Mountain View, California (hereinafter referred to as “INTRABIOTICS”), and NEW CHEMICAL ENTITIES, INC., a Delaware corporation having a principal place of business in Bothell, Washington (hereinafter referred to as “NCE”).

SUBLEASE
Sublease • March 24th, 2008 • Ardea Biosciences, Inc./De • Pharmaceutical preparations

This SUBLEASE (“Sublease”), dated October___, 2007 for reference purposes only, is entered into by and between VERENIUM CORPORATION, a Delaware corporation (“Sublandlord”), and ARDEA BIOSCIENCES, INC., a Delaware corporation (“Subtenant”).

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